您还可以使用CodeFluent Runtime，这是一组免费的工具。它提供了一个SingleInstance类来实现单个实例应用程序。

这就是我最终处理这个问题的方式。注意，调试代码仍然在那里进行测试。这段代码在App.xaml.cs文件的OnStartup中。(WPF)

        // Process already running ? 
        if (Process.GetProcessesByName(Process.GetCurrentProcess().ProcessName).Length > 1)
        {

            // Show your error message
            MessageBox.Show("xxx is already running.  \r\n\r\nIf the original process is hung up you may need to restart your computer, or kill the current xxx process using the task manager.", "xxx is already running!", MessageBoxButton.OK, MessageBoxImage.Exclamation);

            // This process 
            Process currentProcess = Process.GetCurrentProcess();

            // Get all processes running on the local computer.
            Process[] localAll = Process.GetProcessesByName(Process.GetCurrentProcess().ProcessName);

            // ID of this process... 
            int temp = currentProcess.Id;
            MessageBox.Show("This Process ID:  " + temp.ToString());

            for (int i = 0; i < localAll.Length; i++)
            {
                // Find the other process 
                if (localAll[i].Id != currentProcess.Id)
                {
                    MessageBox.Show("Original Process ID (Switching to):  " + localAll[i].Id.ToString());

                    // Switch to it... 
                    SetForegroundWindow(localAll[i].MainWindowHandle);

                }
            }

            Application.Current.Shutdown();

        }

这可能有我还没有发现的问题。如果我遇到了，我会更新我的答案。

通常，这是我用于单实例Windows窗体应用程序的代码:

[STAThread]
public static void Main()
{
    String assemblyName = Assembly.GetExecutingAssembly().GetName().Name;

    using (Mutex mutex = new Mutex(false, assemblyName))
    {
        if (!mutex.WaitOne(0, false))
        {
            Boolean shownProcess = false;
            Process currentProcess = Process.GetCurrentProcess();

            foreach (Process process in Process.GetProcessesByName(currentProcess.ProcessName))
            {
                if (!process.Id.Equals(currentProcess.Id) && process.MainModule.FileName.Equals(currentProcess.MainModule.FileName) && !process.MainWindowHandle.Equals(IntPtr.Zero))
                {
                    IntPtr windowHandle = process.MainWindowHandle;

                    if (NativeMethods.IsIconic(windowHandle))
                        NativeMethods.ShowWindow(windowHandle, ShowWindowCommand.Restore);

                    NativeMethods.SetForegroundWindow(windowHandle);

                    shownProcess = true;
                }
            }

            if (!shownProcess)
                MessageBox.Show(String.Format(CultureInfo.CurrentCulture, "An instance of {0} is already running!", assemblyName), assemblyName, MessageBoxButtons.OK, MessageBoxIcon.Asterisk, MessageBoxDefaultButton.Button1, (MessageBoxOptions)0);
        }
        else
        {
            Application.EnableVisualStyles();
            Application.SetCompatibleTextRenderingDefault(false);
            Application.Run(new Form());
        }
    }
}

本地组件的位置:

[DllImport("User32.dll", CharSet = CharSet.Unicode, ExactSpelling = true, SetLastError = true)]
[return: MarshalAs(UnmanagedType.Bool)]
internal static extern Boolean IsIconic([In] IntPtr windowHandle);

[DllImport("User32.dll", CharSet = CharSet.Unicode, ExactSpelling = true, SetLastError = true)]
[return: MarshalAs(UnmanagedType.Bool)]
internal static extern Boolean SetForegroundWindow([In] IntPtr windowHandle);

[DllImport("User32.dll", CharSet = CharSet.Unicode, ExactSpelling = true, SetLastError = true)]
[return: MarshalAs(UnmanagedType.Bool)]
internal static extern Boolean ShowWindow([In] IntPtr windowHandle, [In] ShowWindowCommand command);

public enum ShowWindowCommand : int
{
    Hide                   = 0x0,
    ShowNormal             = 0x1,
    ShowMinimized          = 0x2,
    ShowMaximized          = 0x3,
    ShowNormalNotActive    = 0x4,
    Minimize               = 0x6,
    ShowMinimizedNotActive = 0x7,
    ShowCurrentNotActive   = 0x8,
    Restore                = 0x9,
    ShowDefault            = 0xA,
    ForceMinimize          = 0xB
}

一个新的使用互斥和IPC的东西，也传递任何命令行参数到运行的实例，是WPF单实例应用程序。

这么简单的问题有这么多答案。稍微改变一下这里是我对这个问题的解决方案。

Creating a Mutex can be troublesome because the JIT-er only sees you using it for a small portion of your code and wants to mark it as ready for garbage collection. It pretty much wants to out-smart you thinking you are not going to be using that Mutex for that long. In reality you want to hang onto this Mutex for as long as your application is running. The best way to tell the garbage collector to leave you Mutex alone is to tell it to keep it alive though out the different generations of garage collection. Example:

var m = new Mutex(...);
...
GC.KeepAlive(m);

我从这个网页上获得了灵感:http://www.ai.uga.edu/~mc/SingleInstance.html

我找到了一个更简单的解决方案，与戴尔·拉根的方法类似，但稍加修改。它基于标准的Microsoft WindowsFormsApplicationBase类，几乎可以做你需要的所有事情。

首先，你创建SingleInstanceController类，你可以在所有其他使用Windows窗体的单实例应用程序中使用它:

using System;
using System.Collections.Generic;
using System.Linq;
using System.Text;
using System.Windows.Forms;
using Microsoft.VisualBasic.ApplicationServices;


namespace SingleInstanceController_NET
{
    public class SingleInstanceController
    : WindowsFormsApplicationBase
    {
        public delegate Form CreateMainForm();
        public delegate void StartNextInstanceDelegate(Form mainWindow);
        CreateMainForm formCreation;
        StartNextInstanceDelegate onStartNextInstance;
        public SingleInstanceController(CreateMainForm formCreation, StartNextInstanceDelegate onStartNextInstance)
        {
            // Set whether the application is single instance
            this.formCreation = formCreation;
            this.onStartNextInstance = onStartNextInstance;
            this.IsSingleInstance = true;

            this.StartupNextInstance += new StartupNextInstanceEventHandler(this_StartupNextInstance);                      
        }

        void this_StartupNextInstance(object sender, StartupNextInstanceEventArgs e)
        {
            if (onStartNextInstance != null)
            {
                onStartNextInstance(this.MainForm); // This code will be executed when the user tries to start the running program again,
                                                    // for example, by clicking on the exe file.
            }                                       // This code can determine how to re-activate the existing main window of the running application.
        }

        protected override void OnCreateMainForm()
        {
            // Instantiate your main application form
            this.MainForm = formCreation();
        }

        public void Run()
        {
            string[] commandLine = new string[0];
            base.Run(commandLine);
        }
    }
}

然后你可以在你的程序中使用它，如下所示:

using System;
using System.Collections.Generic;
using System.Linq;
using System.Windows.Forms;
using SingleInstanceController_NET;

namespace SingleInstance
{
    static class Program
    {
        /// <summary>
        /// The main entry point for the application.
        /// </summary>
        static Form CreateForm()
        {
            return new Form1(); // Form1 is used for the main window.
        }

        static void OnStartNextInstance(Form mainWindow) // When the user tries to restart the application again,
                                                         // the main window is activated again.
        {
            mainWindow.WindowState = FormWindowState.Maximized;
        }
        [STAThread]
        static void Main()
        {
            Application.EnableVisualStyles();
            Application.SetCompatibleTextRenderingDefault(false);            
            SingleInstanceController controller = new SingleInstanceController(CreateForm, OnStartNextInstance);
            controller.Run();         
        }
    }
}

程序和SingleInstanceController_NET解决方案都应该引用Microsoft。VisualBasic。如果您只是想在用户试图重新启动正在运行的程序时重新激活正在运行的应用程序作为一个正常窗口，那么SingleInstanceController中的第二个参数可以为空。在给定的示例中，窗口是最大化的。