我会在KeyDown事件中处理它。

void TextBox_KeyDown(object sender, KeyEventArgs e)
        {
            char c = Convert.ToChar(e.PlatformKeyCode);
            if (!char.IsDigit(c))
            {
                e.Handled = true;
            }
        }

使用Fabio Iotti回答中描述的方法，我创建了一个更通用的解决方案:

public abstract class ValidatedTextBox : TextBox {
    private string m_lastText = string.Empty;
    protected abstract bool IsValid(string text);
    protected sealed override void OnTextChanged(EventArgs e) {
        if (!IsValid(Text)) {
            var pos = SelectionStart - Text.Length + m_lastText.Length;
            Text = m_lastText;
            SelectionStart = Math.Max(0, pos);
        }
        m_lastText = Text;
        base.OnTextChanged(e);
    }
}

"ValidatedTextBox"，它包含了所有重要的验证行为。 剩下要做的就是继承这个类，并使用所需的验证逻辑重写“IsValid”方法。 例如，使用这个类，可以创建"RegexedTextBox"，它只接受匹配特定正则表达式的字符串:

public abstract class RegexedTextBox : ValidatedTextBox {
    private readonly Regex m_regex;
    protected RegexedTextBox(string regExpString) {
        m_regex = new Regex(regExpString);
    }
    protected override bool IsValid(string text) {
        return m_regex.IsMatch(Text);
    }
}

之后，从"RegexedTextBox"类继承，我们可以很容易地创建" positivevenumbertextbox "和"PositiveFloatingPointNumberTextBox"控件:

public sealed class PositiveNumberTextBox : RegexedTextBox {
    public PositiveNumberTextBox() : base(@"^\d*$") { }
}

public sealed class PositiveFloatingPointNumberTextBox : RegexedTextBox {
    public PositiveFloatingPointNumberTextBox()
        : base(@"^(\d+\" + CultureInfo.CurrentCulture.NumberFormat.NumberDecimalSeparator + @")?\d*$") { }
}

你可以使用TextChanged/ Keypress事件，使用正则表达式过滤数字，并采取一些行动。

最简单粗暴的方法是使用组合框而不是带有只读的文本框。当然，只有当你希望用户使用一个合理的整数集，而不是试图接近无穷大时，它才有用。

3解决方案

1)

//Add to the textbox's KeyPress event
//using Regex for number only textBox

private void txtBox_KeyPress(object sender, KeyPressEventArgs e)
{
if (!System.Text.RegularExpressions.Regex.IsMatch(e.KeyChar.ToString(), "\\d+"))
e.Handled = true;
}

2） 来自MSDN的另一个解决方案

// Boolean flag used to determine when a character other than a number is entered.
private bool nonNumberEntered = false;
// Handle the KeyDown event to determine the type of character entered into the     control.
private void textBox1_KeyDown(object sender, KeyEventArgs e)
{
// Initialize the flag to false.
nonNumberEntered = false;
// Determine whether the keystroke is a number from the top of the keyboard.
if (e.KeyCode < Keys.D0 || e.KeyCode > Keys.D9)
{
    // Determine whether the keystroke is a number from the keypad.
    if (e.KeyCode < Keys.NumPad0 || e.KeyCode > Keys.NumPad9)
    {
        // Determine whether the keystroke is a backspace.
        if (e.KeyCode != Keys.Back)
        {
            // A non-numerical keystroke was pressed.
            // Set the flag to true and evaluate in KeyPress event.
            nonNumberEntered = true;
        }
    }
}

}

private void textBox1_KeyPress(object sender, KeyPressEventArgs e)
{
    if (nonNumberEntered == true)
    {
       MessageBox.Show("Please enter number only..."); 
       e.Handled = true;
    }
}

源http://msdn.microsoft.com/en-us/library/system.windows.forms.control.keypress (v =应用程序). aspx

3)使用MaskedTextBox: http://msdn.microsoft.com/en-us/library/system.windows.forms.maskedtextbox.aspx

WPF的工作解决方案&一个简单的TextChangedEventArgs。

private void TextBox_TextChanged(object sender, TextChangedEventArgs e)
{
    var TextBox = (sender as TextBox);

    // if not a numeric value, remove news characters
    if (Regex.IsMatch(TextBox.Text, "[^0-9]"))
    {
        foreach (TextChange Change in e.Changes)
        {
            TextBox.Text = TextBox.Text.Remove(Change.Offset, Change.AddedLength);

            TextBox.CaretIndex = Change.Offset;
        }
    }
}