NSString *str = @"Please enter your text......";
CGSize lblSize = [str sizeWithFont:[UIFont systemFontOfSize:15] constrainedToSize: CGSizeMake(200.0f, 600.0f) lineBreakMode: NSLineBreakByWordWrapping];

UILabel *label = [[UILabel alloc]init];
label.frame = CGRectMake(60, 20, 200, lblSize.height);
label.numberOfLines = 0;
label.lineBreakMode = NSLineBreakByWordWrapping;
label.font = [UIFont systemFontOfSize:15];
label.text = str;
label.backgroundColor = [UIColor clearColor];
[label sizeToFit];
[self.view addSubview:label];

谢谢大家的帮助，这是我尝试的代码，这是为我工作

   UILabel *instructions = [[UILabel alloc]initWithFrame:CGRectMake(10, 225, 300, 180)];
   NSString *text = @"First take clear picture and then try to zoom in to fit the ";
   instructions.text = text;
   instructions.textAlignment = UITextAlignmentCenter;
   instructions.lineBreakMode = NSLineBreakByWordWrapping;
   [instructions setTextColor:[UIColor grayColor]];

   CGSize expectedLabelSize = [text sizeWithFont:instructions.font 
                                constrainedToSize:instructions.frame.size
                                    lineBreakMode:UILineBreakModeWordWrap];

    CGRect newFrame = instructions.frame;
    newFrame.size.height = expectedLabelSize.height;
    instructions.frame = newFrame;
    instructions.numberOfLines = 0;
    [instructions sizeToFit];
    [self addSubview:instructions];

一行是克里斯的答案是错的。

newFrame.size.height = maximumLabelSize.height;

应该是

newFrame.size.height = expectedLabelSize.height;

除此之外，这是正确的解决方案。

当自动布局被启用时，调整大小不工作:)

更新方法

+ (CGFloat)heightForText:(NSString*)text font:(UIFont*)font withinWidth:(CGFloat)width {

    CGSize constraint = CGSizeMake(width, 20000.0f);
    CGSize size;

    CGSize boundingBox = [text boundingRectWithSize:constraint
                                                  options:NSStringDrawingUsesLineFragmentOrigin
                                               attributes:@{NSFontAttributeName:font}
                                                  context:nil].size;

    size = CGSizeMake(ceil(boundingBox.width), ceil(boundingBox.height));

    return size.height;
}

-(UITableViewCell *)tableView:(UITableView *)tableView cellForRowAtIndexPath:(NSIndexPath *)indexPath
{
    cellIdentifier = @"myCell";
    cell = [tableView dequeueReusableCellWithIdentifier:cellIdentifier];
    cell.myUILabel.lineBreakMode = UILineBreakModeWordWrap;        
    cell.myUILabel.numberOfLines = 0;
    cell.myUILabel.text = @"Some very very very very long text....."
    [cell.myUILabel.criterionDescriptionLabel sizeToFit];    
}

- (CGFloat)tableView:(UITableView *)tableView heightForRowAtIndexPath:(NSIndexPath *)indexPath
{
    UITableViewCell *cell = [self tableView:tableView cellForRowAtIndexPath:indexPath];
    CGFloat rowHeight = cell.myUILabel.frame.size.height + 10;

    return rowHeight;    
}