我认为如果你把文件读入一个列表，然后你可以遍历这个列表来寻找你想要去掉的昵称。您可以在不创建额外文件的情况下高效地执行此操作，但必须将结果写回源文件。

以下是我可能的做法:

import, os, csv # and other imports you need
nicknames_to_delete = ['Nick', 'Stephen', 'Mark']

我假设nicknames.csv包含如下数据:

Nick
Maria
James
Chris
Mario
Stephen
Isabella
Ahmed
Julia
Mark
...

然后将文件加载到列表中:

 nicknames = None
 with open("nicknames.csv") as sourceFile:
     nicknames = sourceFile.read().splitlines()

接下来，迭代到list以匹配要删除的输入:

for nick in nicknames_to_delete:
     try:
         if nick in nicknames:
             nicknames.pop(nicknames.index(nick))
         else:
             print(nick + " is not found in the file")
     except ValueError:
         pass

最后，将结果写回文件:

with open("nicknames.csv", "a") as nicknamesFile:
    nicknamesFile.seek(0)
    nicknamesFile.truncate()
    nicknamesWriter = csv.writer(nicknamesFile)
    for name in nicknames:
        nicknamesWriter.writeRow([str(name)])
nicknamesFile.close()

下面是其他一些从文件中删除/some行的方法:

src_file = zzzz.txt
f = open(src_file, "r")
contents = f.readlines()
f.close()

contents.pop(idx) # remove the line item from list, by line number, starts from 0

f = open(src_file, "w")
contents = "".join(contents)
f.write(contents)
f.close()

按行号删除文件中的某一行。

用文件名和要删除的行号替换变量filename和line_to_delete。

filename = 'foo.txt'
line_to_delete = 3
initial_line = 1
file_lines = {}

with open(filename) as f:
    content = f.readlines() 

for line in content:
    file_lines[initial_line] = line.strip()
    initial_line += 1

f = open(filename, "w")
for line_number, line_content in file_lines.items():
    if line_number != line_to_delete:
        f.write('{}\n'.format(line_content))

f.close()
print('Deleted line: {}'.format(line_to_delete))

示例输出:

Deleted line: 3

也许你已经有了正确答案，但下面是我的答案。 我没有使用列表来收集未经过滤的数据(readlines()方法所做的)，而是使用了两个文件。一个用于保存主数据，第二个用于在删除特定字符串时过滤数据。这是一个代码:

main_file = open('data_base.txt').read()    # your main dataBase file
filter_file = open('filter_base.txt', 'w')
filter_file.write(main_file)
filter_file.close()
main_file = open('data_base.txt', 'w')
for line in open('filter_base'):
    if 'your data to delete' not in line:    # remove a specific string
        main_file.write(line)                # put all strings back to your db except deleted
    else: pass
main_file.close()

希望你会发现这有用!：）

将文件行保存在一个列表中，然后从列表中删除要删除的行，并将剩余的行写入一个新文件

with open("file_name.txt", "r") as f:
    lines = f.readlines() 
    lines.remove("Line you want to delete\n")
    with open("new_file.txt", "w") as new_f:
        for line in lines:        
            new_f.write(line)

你想从文件中删除特定的行，所以使用这个简短的代码片段，你可以很容易地删除任何带有句子或前缀(符号)的行。

with open("file_name.txt", "r") as f:
lines = f.readlines() 
with open("new_file.txt", "w") as new_f:
    for line in lines:
        if not line.startswith("write any sentence or symbol to remove line"):
            new_f.write(line)