你可以在文本框的textchanged事件中这样做。

这是一个演示

    private void textBox1_TextChanged(object sender, EventArgs e)
    {
        string actualdata = string.Empty;
        char[] entereddata = textBox1.Text.ToCharArray();
        foreach (char aChar in entereddata.AsEnumerable())
        {
            if (Char.IsDigit(aChar))
            {
                actualdata = actualdata + aChar;
                // MessageBox.Show(aChar.ToString());
            }
            else
            {
                MessageBox.Show(aChar + " is not numeric");
                actualdata.Replace(aChar, ' ');
                actualdata.Trim();
            }
        }
        textBox1.Text = actualdata;
    }

这是一个简单的独立的Winforms自定义控件，从标准的TextBox派生而来，只允许System。Int32输入(它可以很容易地适用于其他类型，如System。Int64,等等)。它支持复制/粘贴操作和负数:

public class Int32TextBox : TextBox
{
    protected override void OnKeyPress(KeyPressEventArgs e)
    {
        base.OnKeyPress(e);

        NumberFormatInfo fi = CultureInfo.CurrentCulture.NumberFormat;

        string c = e.KeyChar.ToString();
        if (char.IsDigit(c, 0))
            return;

        if ((SelectionStart == 0) && (c.Equals(fi.NegativeSign)))
            return;

        // copy/paste
        if ((((int)e.KeyChar == 22) || ((int)e.KeyChar == 3))
            && ((ModifierKeys & Keys.Control) == Keys.Control))
            return;

        if (e.KeyChar == '\b')
            return;

        e.Handled = true;
    }

    protected override void WndProc(ref System.Windows.Forms.Message m)
    {
        const int WM_PASTE = 0x0302;
        if (m.Msg == WM_PASTE)
        {
            string text = Clipboard.GetText();
            if (string.IsNullOrEmpty(text))
                return;

            if ((text.IndexOf('+') >= 0) && (SelectionStart != 0))
                return;

            int i;
            if (!int.TryParse(text, out i)) // change this for other integer types
                return;

            if ((i < 0) && (SelectionStart != 0))
                return;
        }
        base.WndProc(ref m);
    }

2017年更新:我的第一个答案有一些问题:

你可以输入一个比给定类型的整数更长的值(例如2147483648大于Int32.MaxValue); 更一般地说，对于输入的结果没有真正的验证; 它只处理int32，你必须写特定的TextBox衍生控件为每种类型(Int64等)

所以我提出了另一个更通用的版本，它仍然支持复制/粘贴，+和-号等。

public class ValidatingTextBox : TextBox
{
    private string _validText;
    private int _selectionStart;
    private int _selectionEnd;
    private bool _dontProcessMessages;

    public event EventHandler<TextValidatingEventArgs> TextValidating;

    protected virtual void OnTextValidating(object sender, TextValidatingEventArgs e) => TextValidating?.Invoke(sender, e);

    protected override void WndProc(ref Message m)
    {
        base.WndProc(ref m);
        if (_dontProcessMessages)
            return;

        const int WM_KEYDOWN = 0x100;
        const int WM_ENTERIDLE = 0x121;
        const int VK_DELETE = 0x2e;

        bool delete = m.Msg == WM_KEYDOWN && (int)m.WParam == VK_DELETE;
        if ((m.Msg == WM_KEYDOWN && !delete) || m.Msg == WM_ENTERIDLE)
        {
            DontProcessMessage(() =>
            {
                _validText = Text;
                _selectionStart = SelectionStart;
                _selectionEnd = SelectionLength;
            });
        }

        const int WM_CHAR = 0x102;
        const int WM_PASTE = 0x302;
        if (m.Msg == WM_CHAR || m.Msg == WM_PASTE || delete)
        {
            string newText = null;
            DontProcessMessage(() =>
            {
                newText = Text;
            });

            var e = new TextValidatingEventArgs(newText);
            OnTextValidating(this, e);
            if (e.Cancel)
            {
                DontProcessMessage(() =>
                {
                    Text = _validText;
                    SelectionStart = _selectionStart;
                    SelectionLength = _selectionEnd;
                });
            }
        }
    }

    private void DontProcessMessage(Action action)
    {
        _dontProcessMessages = true;
        try
        {
            action();
        }
        finally
        {
            _dontProcessMessages = false;
        }
    }
}

public class TextValidatingEventArgs : CancelEventArgs
{
    public TextValidatingEventArgs(string newText) => NewText = newText;
    public string NewText { get; }
}

对于Int32，你可以从它导出，像这样:

public class Int32TextBox : ValidatingTextBox
{
    protected override void OnTextValidating(object sender, TextValidatingEventArgs e)
    {
        e.Cancel = !int.TryParse(e.NewText, out int i);
    }
}

或w/o派生，使用新的textvalididating事件，像这样:

var vtb = new ValidatingTextBox();
...
vtb.TextValidating += (sender, e) => e.Cancel = !int.TryParse(e.NewText, out int i);

但它的优点是它适用于任何字符串和任何验证例程。

似乎目前对这个问题的许多答案都是手动解析输入文本。如果你正在寻找一个特定的内置数字类型(例如int或double)，为什么不只是将工作委托给该类型的TryParse方法?例如:

public class IntTextBox : TextBox
{
    string PreviousText = "";
    int BackingResult;

    public IntTextBox()
    {
        TextChanged += IntTextBox_TextChanged;
    }

    public bool HasResult { get; private set; }

    public int Result
    {
        get
        {
            return HasResult ? BackingResult : default(int);
        }
    }

    void IntTextBox_TextChanged(object sender, EventArgs e)
    {
        HasResult = int.TryParse(Text, out BackingResult);

        if (HasResult || string.IsNullOrEmpty(Text))
        {
            // Commit
            PreviousText = Text;
        }
        else
        {
            // Revert
            var changeOffset = Text.Length - PreviousText.Length;
            var previousSelectionStart =
                Math.Max(0, SelectionStart - changeOffset);

            Text = PreviousText;
            SelectionStart = previousSelectionStart;
        }
    }
}

如果你想要更通用但仍然兼容Visual Studio的设计器:

public class ParsableTextBox : TextBox
{
    TryParser BackingTryParse;
    string PreviousText = "";
    object BackingResult;

    public ParsableTextBox()
        : this(null)
    {
    }

    public ParsableTextBox(TryParser tryParse)
    {
        TryParse = tryParse;

        TextChanged += ParsableTextBox_TextChanged;
    }

    public delegate bool TryParser(string text, out object result);

    public TryParser TryParse
    {
        set
        {
            Enabled = !(ReadOnly = value == null);

            BackingTryParse = value;
        }
    }

    public bool HasResult { get; private set; }

    public object Result
    {
        get
        {
            return GetResult<object>();
        }
    }

    public T GetResult<T>()
    {
        return HasResult ? (T)BackingResult : default(T);
    }

    void ParsableTextBox_TextChanged(object sender, EventArgs e)
    {
        if (BackingTryParse != null)
        {
            HasResult = BackingTryParse(Text, out BackingResult);
        }

        if (HasResult || string.IsNullOrEmpty(Text))
        {
            // Commit
            PreviousText = Text;
        }
        else
        {
            // Revert
            var changeOffset = Text.Length - PreviousText.Length;
            var previousSelectionStart =
                Math.Max(0, SelectionStart - changeOffset);

            Text = PreviousText;
            SelectionStart = previousSelectionStart;
        }
    }
}

最后，如果你想要完全通用的东西，不关心Designer支持:

public class ParsableTextBox<T> : TextBox
{
    TryParser BackingTryParse;
    string PreviousText;
    T BackingResult;

    public ParsableTextBox()
        : this(null)
    {
    }

    public ParsableTextBox(TryParser tryParse)
    {
        TryParse = tryParse;

        TextChanged += ParsableTextBox_TextChanged;
    }

    public delegate bool TryParser(string text, out T result);

    public TryParser TryParse
    {
        set
        {
            Enabled = !(ReadOnly = value == null);

            BackingTryParse = value;
        }
    }

    public bool HasResult { get; private set; }

    public T Result
    {
        get
        {
            return HasResult ? BackingResult : default(T);
        }
    }

    void ParsableTextBox_TextChanged(object sender, EventArgs e)
    {
        if (BackingTryParse != null)
        {
            HasResult = BackingTryParse(Text, out BackingResult);
        }

        if (HasResult || string.IsNullOrEmpty(Text))
        {
            // Commit
            PreviousText = Text;
        }
        else
        {
            // Revert
            var changeOffset = Text.Length - PreviousText.Length;
            var previousSelectionStart =
                Math.Max(0, SelectionStart - changeOffset);

            Text = PreviousText;
            SelectionStart = previousSelectionStart;
        }
    }
}

看一下WinForm中的输入处理

我已经发布了我的解决方案，在文本框上使用ProcessCmdKey和OnKeyPress事件。注释向您展示了如何使用Regex来验证键按和适当地阻止/允许。

使用正则表达式验证器:

<asp:TextBox ID="TextBoxNum" runat="server"></asp:TextBox><br />
<asp:RegularExpressionValidator ID="RegularExpressionValidator1"
                        ControlToValidate="TextBoxNum" runat="server"
                        ErrorMessage="Only numbers allowed"
                        ValidationExpression="\d+">
</asp:RegularExpressionValidator>

允许一行代码小数点

    private void txtQty_KeyPress(object sender, KeyPressEventArgs e)
    {
        e.Handled =  e.KeyChar != '.' && !char.IsDigit(e.KeyChar) && !char.IsControl(e.KeyChar);
    }