你可以在文本框的textchanged事件中这样做。

这是一个演示

    private void textBox1_TextChanged(object sender, EventArgs e)
    {
        string actualdata = string.Empty;
        char[] entereddata = textBox1.Text.ToCharArray();
        foreach (char aChar in entereddata.AsEnumerable())
        {
            if (Char.IsDigit(aChar))
            {
                actualdata = actualdata + aChar;
                // MessageBox.Show(aChar.ToString());
            }
            else
            {
                MessageBox.Show(aChar + " is not numeric");
                actualdata.Replace(aChar, ' ');
                actualdata.Trim();
            }
        }
        textBox1.Text = actualdata;
    }

这正是设计已验证/正在验证事件的目的。

下面是MSDN上关于这个主题的文章:http://msdn.microsoft.com/en-us/library/system.windows.forms.control.validating.aspx

TL;DR版本:检查validate事件中的. text属性，并在数据无效时设置e.Cancel=True。

当你设置e.Cancel=True时，用户不能离开这个字段，但是你需要给他们一些错误的反馈。我将方框的背景颜色更改为浅红色，以表示有问题。确保将其设置回SystemColors。窗口时调用一个良好的值。

我也在寻找最好的方法来检查文本框中只有数字和键盘的问题是，它不支持通过右键单击或剪贴板复制粘贴，所以提出了这个代码，验证光标离开文本字段时，它也检查空字段。(newguy改编版)

private void txtFirstValue_MouseLeave(object sender, EventArgs e)
{
    int num;
    bool isNum = int.TryParse(txtFirstValue.Text.Trim(), out num);

    if (!isNum && txtFirstValue.Text != String.Empty)
    {
        MessageBox.Show("The First Value You Entered Is Not a Number, Please Try Again", "Invalid Value Detected", MessageBoxButtons.OK, MessageBoxIcon.Error);
        txtFirstValue.Clear();
    }
}

使用Fabio Iotti回答中描述的方法，我创建了一个更通用的解决方案:

public abstract class ValidatedTextBox : TextBox {
    private string m_lastText = string.Empty;
    protected abstract bool IsValid(string text);
    protected sealed override void OnTextChanged(EventArgs e) {
        if (!IsValid(Text)) {
            var pos = SelectionStart - Text.Length + m_lastText.Length;
            Text = m_lastText;
            SelectionStart = Math.Max(0, pos);
        }
        m_lastText = Text;
        base.OnTextChanged(e);
    }
}

"ValidatedTextBox"，它包含了所有重要的验证行为。 剩下要做的就是继承这个类，并使用所需的验证逻辑重写“IsValid”方法。 例如，使用这个类，可以创建"RegexedTextBox"，它只接受匹配特定正则表达式的字符串:

public abstract class RegexedTextBox : ValidatedTextBox {
    private readonly Regex m_regex;
    protected RegexedTextBox(string regExpString) {
        m_regex = new Regex(regExpString);
    }
    protected override bool IsValid(string text) {
        return m_regex.IsMatch(Text);
    }
}

之后，从"RegexedTextBox"类继承，我们可以很容易地创建" positivevenumbertextbox "和"PositiveFloatingPointNumberTextBox"控件:

public sealed class PositiveNumberTextBox : RegexedTextBox {
    public PositiveNumberTextBox() : base(@"^\d*$") { }
}

public sealed class PositiveFloatingPointNumberTextBox : RegexedTextBox {
    public PositiveFloatingPointNumberTextBox()
        : base(@"^(\d+\" + CultureInfo.CurrentCulture.NumberFormat.NumberDecimalSeparator + @")?\d*$") { }
}

很抱歉吵醒死人，但我想有人可能会觉得这对将来的参考有用。

以下是我的处理方法。它处理浮点数，但可以很容易地修改为整数。

基本上你只能按0 - 9和。

前面只能有一个0。

所有其他字符将被忽略，光标位置保持不变。

    private bool _myTextBoxChanging = false;

    private void myTextBox_TextChanged(object sender, EventArgs e)
    {
        validateText(myTextBox);
    }

    private void validateText(TextBox box)
    {
        // stop multiple changes;
        if (_myTextBoxChanging)
            return;
        _myTextBoxChanging = true;

        string text = box.Text;
        if (text == "")
            return;
        string validText = "";
        bool hasPeriod = false;
        int pos = box.SelectionStart;
        for (int i = 0; i < text.Length; i++ )
        {
            bool badChar = false;
            char s = text[i];
            if (s == '.')
            {
                if (hasPeriod)
                    badChar = true;
                else
                    hasPeriod = true;
            }
            else if (s < '0' || s > '9')
                badChar = true;

            if (!badChar)
                validText += s;
            else
            {
                if (i <= pos)
                    pos--;
            }
        }

        // trim starting 00s
        while (validText.Length >= 2 && validText[0] == '0')
        {
            if (validText[1] != '.')
            {
                validText = validText.Substring(1);
                if (pos < 2)
                    pos--;
            }
            else
                break;
        }

        if (pos > validText.Length)
            pos = validText.Length;
        box.Text = validText;
        box.SelectionStart = pos;
        _myTextBoxChanging = false;
    }

下面是一个快速修改的int版本:

    private void validateText(TextBox box)
    {
        // stop multiple changes;
        if (_myTextBoxChanging)
            return;
        _myTextBoxChanging = true;

        string text = box.Text;
        if (text == "")
            return;
        string validText = "";
        int pos = box.SelectionStart;
        for (int i = 0; i < text.Length; i++ )
        {
            char s = text[i];
            if (s < '0' || s > '9')
            {
                if (i <= pos)
                    pos--;
            }
            else
                validText += s;
        }

        // trim starting 00s 
        while (validText.Length >= 2 && validText.StartsWith("00")) 
        { 
            validText = validText.Substring(1); 
            if (pos < 2) 
                pos--; 
        } 

        if (pos > validText.Length)
            pos = validText.Length;
        box.Text = validText;
        box.SelectionStart = pos;
        _myTextBoxChanging = false;
    }

这可能有用。它允许“真实”数值，包括正确的小数点和前面的加号或减号。从相关的KeyPress事件中调用它。

       private bool IsOKForDecimalTextBox(char theCharacter, TextBox theTextBox)
    {
        // Only allow control characters, digits, plus and minus signs.
        // Only allow ONE plus sign.
        // Only allow ONE minus sign.
        // Only allow the plus or minus sign as the FIRST character.
        // Only allow ONE decimal point.
        // Do NOT allow decimal point or digits BEFORE any plus or minus sign.

        if (
            !char.IsControl(theCharacter)
            && !char.IsDigit(theCharacter)
            && (theCharacter != '.')
            && (theCharacter != '-')
            && (theCharacter != '+')
        )
        {
            // Then it is NOT a character we want allowed in the text box.
            return false;
        }



        // Only allow one decimal point.
        if (theCharacter == '.'
            && theTextBox.Text.IndexOf('.') > -1)
        {
            // Then there is already a decimal point in the text box.
            return false;
        }

        // Only allow one minus sign.
        if (theCharacter == '-'
            && theTextBox.Text.IndexOf('-') > -1)
        {
            // Then there is already a minus sign in the text box.
            return false;
        }

        // Only allow one plus sign.
        if (theCharacter == '+'
            && theTextBox.Text.IndexOf('+') > -1)
        {
            // Then there is already a plus sign in the text box.
            return false;
        }

        // Only allow one plus sign OR minus sign, but not both.
        if (
            (
                (theCharacter == '-')
                || (theCharacter == '+')
            )
            && 
            (
                (theTextBox.Text.IndexOf('-') > -1)
                ||
                (theTextBox.Text.IndexOf('+') > -1)
            )
            )
        {
            // Then the user is trying to enter a plus or minus sign and
            // there is ALREADY a plus or minus sign in the text box.
            return false;
        }

        // Only allow a minus or plus sign at the first character position.
        if (
            (
                (theCharacter == '-')
                || (theCharacter == '+')
            )
            && theTextBox.SelectionStart != 0
            )
        {
            // Then the user is trying to enter a minus or plus sign at some position 
            // OTHER than the first character position in the text box.
            return false;
        }

        // Only allow digits and decimal point AFTER any existing plus or minus sign
        if  (
                (
                    // Is digit or decimal point
                    char.IsDigit(theCharacter)
                    ||
                    (theCharacter == '.')
                )
                &&
                (
                    // A plus or minus sign EXISTS
                    (theTextBox.Text.IndexOf('-') > -1)
                    ||
                    (theTextBox.Text.IndexOf('+') > -1)
                )
                &&
                    // Attempting to put the character at the beginning of the field.
                    theTextBox.SelectionStart == 0
            )
        {
            // Then the user is trying to enter a digit or decimal point in front of a minus or plus sign.
            return false;
        }

        // Otherwise the character is perfectly fine for a decimal value and the character
        // may indeed be placed at the current insertion position.
        return true;
    }