这是用.NET 5/Core来实现的一种很好很短的方法

private void textBox1_KeyDown(object sender, KeyEventArgs e) {
  if (e.KeyData != Keys.Back)
    e.SuppressKeyPress = !int.TryParse(Convert.ToString((char) e.KeyData), out int _);
}

编辑:增加了退格键的支持

尝试一个MaskedTextBox。它采用一种简单的掩码格式，这样你就可以将输入限制为数字或日期之类的。

我从上下文和您使用的标记假设您正在编写一个。net c#应用程序。在这种情况下，您可以订阅文本更改事件，并验证每个按键。

private void textBox1_TextChanged(object sender, EventArgs e)
{
    if (System.Text.RegularExpressions.Regex.IsMatch(textBox1.Text, "[^0-9]"))
    {
        MessageBox.Show("Please enter only numbers.");
        textBox1.Text = textBox1.Text.Remove(textBox1.Text.Length - 1);
    }
}

我喜欢简洁的代码

    private void xmm_textbox_KeyPress(object sender, KeyPressEventArgs e) {
        double x;
        e.Handled = !double.TryParse(((TextBox)sender).Text, out x);
    }

这可能有用。它允许“真实”数值，包括正确的小数点和前面的加号或减号。从相关的KeyPress事件中调用它。

       private bool IsOKForDecimalTextBox(char theCharacter, TextBox theTextBox)
    {
        // Only allow control characters, digits, plus and minus signs.
        // Only allow ONE plus sign.
        // Only allow ONE minus sign.
        // Only allow the plus or minus sign as the FIRST character.
        // Only allow ONE decimal point.
        // Do NOT allow decimal point or digits BEFORE any plus or minus sign.

        if (
            !char.IsControl(theCharacter)
            && !char.IsDigit(theCharacter)
            && (theCharacter != '.')
            && (theCharacter != '-')
            && (theCharacter != '+')
        )
        {
            // Then it is NOT a character we want allowed in the text box.
            return false;
        }



        // Only allow one decimal point.
        if (theCharacter == '.'
            && theTextBox.Text.IndexOf('.') > -1)
        {
            // Then there is already a decimal point in the text box.
            return false;
        }

        // Only allow one minus sign.
        if (theCharacter == '-'
            && theTextBox.Text.IndexOf('-') > -1)
        {
            // Then there is already a minus sign in the text box.
            return false;
        }

        // Only allow one plus sign.
        if (theCharacter == '+'
            && theTextBox.Text.IndexOf('+') > -1)
        {
            // Then there is already a plus sign in the text box.
            return false;
        }

        // Only allow one plus sign OR minus sign, but not both.
        if (
            (
                (theCharacter == '-')
                || (theCharacter == '+')
            )
            && 
            (
                (theTextBox.Text.IndexOf('-') > -1)
                ||
                (theTextBox.Text.IndexOf('+') > -1)
            )
            )
        {
            // Then the user is trying to enter a plus or minus sign and
            // there is ALREADY a plus or minus sign in the text box.
            return false;
        }

        // Only allow a minus or plus sign at the first character position.
        if (
            (
                (theCharacter == '-')
                || (theCharacter == '+')
            )
            && theTextBox.SelectionStart != 0
            )
        {
            // Then the user is trying to enter a minus or plus sign at some position 
            // OTHER than the first character position in the text box.
            return false;
        }

        // Only allow digits and decimal point AFTER any existing plus or minus sign
        if  (
                (
                    // Is digit or decimal point
                    char.IsDigit(theCharacter)
                    ||
                    (theCharacter == '.')
                )
                &&
                (
                    // A plus or minus sign EXISTS
                    (theTextBox.Text.IndexOf('-') > -1)
                    ||
                    (theTextBox.Text.IndexOf('+') > -1)
                )
                &&
                    // Attempting to put the character at the beginning of the field.
                    theTextBox.SelectionStart == 0
            )
        {
            // Then the user is trying to enter a digit or decimal point in front of a minus or plus sign.
            return false;
        }

        // Otherwise the character is perfectly fine for a decimal value and the character
        // may indeed be placed at the current insertion position.
        return true;
    }

很抱歉吵醒死人，但我想有人可能会觉得这对将来的参考有用。

以下是我的处理方法。它处理浮点数，但可以很容易地修改为整数。

基本上你只能按0 - 9和。

前面只能有一个0。

所有其他字符将被忽略，光标位置保持不变。

    private bool _myTextBoxChanging = false;

    private void myTextBox_TextChanged(object sender, EventArgs e)
    {
        validateText(myTextBox);
    }

    private void validateText(TextBox box)
    {
        // stop multiple changes;
        if (_myTextBoxChanging)
            return;
        _myTextBoxChanging = true;

        string text = box.Text;
        if (text == "")
            return;
        string validText = "";
        bool hasPeriod = false;
        int pos = box.SelectionStart;
        for (int i = 0; i < text.Length; i++ )
        {
            bool badChar = false;
            char s = text[i];
            if (s == '.')
            {
                if (hasPeriod)
                    badChar = true;
                else
                    hasPeriod = true;
            }
            else if (s < '0' || s > '9')
                badChar = true;

            if (!badChar)
                validText += s;
            else
            {
                if (i <= pos)
                    pos--;
            }
        }

        // trim starting 00s
        while (validText.Length >= 2 && validText[0] == '0')
        {
            if (validText[1] != '.')
            {
                validText = validText.Substring(1);
                if (pos < 2)
                    pos--;
            }
            else
                break;
        }

        if (pos > validText.Length)
            pos = validText.Length;
        box.Text = validText;
        box.SelectionStart = pos;
        _myTextBoxChanging = false;
    }

下面是一个快速修改的int版本:

    private void validateText(TextBox box)
    {
        // stop multiple changes;
        if (_myTextBoxChanging)
            return;
        _myTextBoxChanging = true;

        string text = box.Text;
        if (text == "")
            return;
        string validText = "";
        int pos = box.SelectionStart;
        for (int i = 0; i < text.Length; i++ )
        {
            char s = text[i];
            if (s < '0' || s > '9')
            {
                if (i <= pos)
                    pos--;
            }
            else
                validText += s;
        }

        // trim starting 00s 
        while (validText.Length >= 2 && validText.StartsWith("00")) 
        { 
            validText = validText.Substring(1); 
            if (pos < 2) 
                pos--; 
        } 

        if (pos > validText.Length)
            pos = validText.Length;
        box.Text = validText;
        box.SelectionStart = pos;
        _myTextBoxChanging = false;
    }