这是我找到的最简单的解决方法:

斯威夫特4

class CustomLabel: UILabel{
    override func drawText(in rect: CGRect) {
        super.drawText(in: rect.inset(by: UIEdgeInsets.init(top: 10, left: 10, bottom: 10, right: 10)))
    }
}

确保在代码和故事板中都将标签设置为CustomLabel类。

Swift 3 &自动布局兼容版本:

class InsetLabel: UILabel {

    var insets = UIEdgeInsets()

    convenience init(insets: UIEdgeInsets) {
        self.init(frame: CGRect.zero)
        self.insets = insets
    }

    convenience init(dx: CGFloat, dy: CGFloat) {
        let insets = UIEdgeInsets(top: dy, left: dx, bottom: dy, right: dx)
        self.init(insets: insets)
    }

    override func drawText(in rect: CGRect) {
        super.drawText(in: UIEdgeInsetsInsetRect(rect, insets))
    }

    override var intrinsicContentSize: CGSize  {
        var size = super.intrinsicContentSize
        size.width += insets.left + insets.right
        size.height += insets.top + insets.bottom
        return size
    }
}

我认为UILabel类没有设置边距的方法。为什么不把标签的位置设置在需要的位置?

见下面的代码:

UILabel *label = [[UILabel alloc] init];
label.text = @"This is label";
label.frame = CGRectMake(0,0,100,100);

如果来自接口构建器，则按以下方式定位Label:

yourLabel.frame = CGRectMake(0,0,100,100);

可以使用https://github.com/mattt/TTTAttributedLabel代替UILabel

BITAttributedLabel *label = [BITAttributedLabel new];
label.font = font;
label.text = @"hello";
label.textInsets = UIEdgeInsetsMake(10, 10, 10, 10);
[label sizeToFit];

不要编码，Xcode !

比起使用UILabel来解决这个问题，我建议你去看看UIButton。它提供了开箱即用的功能，可以在大小检查器中设置内容插入(上、左、下、右)。设置所需的边距，然后在Xcode中禁用按钮，完成。

对于Xamarin用户(使用统一API):

class UIMarginLabel : UILabel
{
    public UIMarginLabel()
    {
    }

    public UIMarginLabel( CGRect frame ) : base( frame )
    {
    }

    public UIEdgeInsets Insets { get; set; }

    public override void DrawText( CGRect rect )
    {
        base.DrawText( Insets.InsetRect( rect ) );
    }
}

对于那些使用原始MonoTouch API的人:

public class UIMarginLabel : UILabel
{
    public UIEdgeInsets Insets { get; set; }

    public UIMarginLabel() : base()
    {
        Insets = new UIEdgeInsets(0, 0, 0, 0);
    }
    public UIMarginLabel(RectangleF frame) : base(frame)
    {
        Insets = new UIEdgeInsets(0, 0, 0, 0);
    }

    public override void DrawText(RectangleF frame)
    {
        base.DrawText(new RectangleF(
            frame.X + Insets.Left,
            frame.Y + Insets.Top,
            frame.Width - Insets.Left - Insets.Right,
            frame.Height - Insets.Top - Insets.Bottom));
    }
}