这两种方法都有效：

  Uri final = new Uri(Regex.Replace(baseUrl + "/" + relativePath, "(?<!http:)/{2,}", "/"));

Or

  Uri final =new Uri(string.Format("{0}/{1}", baseUrl.ToString().TrimEnd('/'), relativePath.ToString().TrimStart('/')));

即，如果

baseUrl = "http://tesrurl.test.com/Int18"

and

relativePath = "To_Folder"

output = http://tesrurl.test.com/Int18/To_Folder

以下代码将出现一些错误：

 // If you use the below code, some issues will be there in the final URI
 Uri final = new Uri(baseUrl, relativePath);

如果您不想拥有像Flurl这样的依赖项，可以使用它的源代码：

    /// <summary>
    /// Basically a Path.Combine for URLs. Ensures exactly one '/' separates each segment,
    /// and exactly on '&amp;' separates each query parameter.
    /// URL-encodes illegal characters but not reserved characters.
    /// </summary>
    /// <param name="parts">URL parts to combine.</param>
    public static string Combine(params string[] parts) {
        if (parts == null)
            throw new ArgumentNullException(nameof(parts));

        string result = "";
        bool inQuery = false, inFragment = false;

        string CombineEnsureSingleSeparator(string a, string b, char separator) {
            if (string.IsNullOrEmpty(a)) return b;
            if (string.IsNullOrEmpty(b)) return a;
            return a.TrimEnd(separator) + separator + b.TrimStart(separator);
        }

        foreach (var part in parts) {
            if (string.IsNullOrEmpty(part))
                continue;

            if (result.EndsWith("?") || part.StartsWith("?"))
                result = CombineEnsureSingleSeparator(result, part, '?');
            else if (result.EndsWith("#") || part.StartsWith("#"))
                result = CombineEnsureSingleSeparator(result, part, '#');
            else if (inFragment)
                result += part;
            else if (inQuery)
                result = CombineEnsureSingleSeparator(result, part, '&');
            else
                result = CombineEnsureSingleSeparator(result, part, '/');

            if (part.Contains("#")) {
                inQuery = false;
                inFragment = true;
            }
            else if (!inFragment && part.Contains("?")) {
                inQuery = true;
            }
        }
        return EncodeIllegalCharacters(result);
    }

    /// <summary>
    /// URL-encodes characters in a string that are neither reserved nor unreserved. Avoids encoding reserved characters such as '/' and '?'. Avoids encoding '%' if it begins a %-hex-hex sequence (i.e. avoids double-encoding).
    /// </summary>
    /// <param name="s">The string to encode.</param>
    /// <param name="encodeSpaceAsPlus">If true, spaces will be encoded as + signs. Otherwise, they'll be encoded as %20.</param>
    /// <returns>The encoded URL.</returns>
    public static string EncodeIllegalCharacters(string s, bool encodeSpaceAsPlus = false) {
        if (string.IsNullOrEmpty(s))
            return s;

        if (encodeSpaceAsPlus)
            s = s.Replace(" ", "+");

        // Uri.EscapeUriString mostly does what we want - encodes illegal characters only - but it has a quirk
        // in that % isn't illegal if it's the start of a %-encoded sequence https://stackoverflow.com/a/47636037/62600

        // no % characters, so avoid the regex overhead
        if (!s.Contains("%"))
            return Uri.EscapeUriString(s);

        // pick out all %-hex-hex matches and avoid double-encoding 
        return Regex.Replace(s, "(.*?)((%[0-9A-Fa-f]{2})|$)", c => {
            var a = c.Groups[1].Value; // group 1 is a sequence with no %-encoding - encode illegal characters
            var b = c.Groups[2].Value; // group 2 is a valid 3-character %-encoded sequence - leave it alone!
            return Uri.EscapeUriString(a) + b;
        });
    }

值得一提的是，这里有几个扩展方法。第一个将合并路径，第二个将向URL添加参数。

    public static string CombineUrl(this string root, string path, params string[] paths)
    {
        if (string.IsNullOrWhiteSpace(path))
        {
            return root;
        }

        Uri baseUri = new Uri(root);
        Uri combinedPaths = new Uri(baseUri, path);

        foreach (string extendedPath in paths)
        {
           combinedPaths = new Uri(combinedPaths, extendedPath);
        }

        return combinedPaths.AbsoluteUri;
    }

    public static string AddUrlParams(this string url, Dictionary<string, string> parameters)
    {
        if (parameters == null || !parameters.Keys.Any())
        {
            return url;
        }

        var tempUrl = new StringBuilder($"{url}?");
        int count = 0;

        foreach (KeyValuePair<string, string> parameter in parameters)
        {
            if (count > 0)
            {
                tempUrl.Append("&");
            }

            tempUrl.Append($"{WebUtility.UrlEncode(parameter.Key)}={WebUtility.UrlEncode(parameter.Value)}");
            count++;
        }

        return tempUrl.ToString();
    }

如果您不想在ASP.NET Core（也在Microsoft.Owin中提供）中添加第三方依赖项（如Flurl）或创建自定义扩展方法，则可以使用PathString来构建URI路径。然后，可以使用URI和UriBuilder的组合创建完整的URI。

在这种情况下，应为：

new Uri(new UriBuilder("http", "MyUrl.com").Uri, new PathString("/Images").Add("/Image.jpg").ToString())

这提供了所有组成部分，而无需在基URL中指定分隔符。不幸的是，PathString要求在每个字符串前面加上/，否则它实际上会引发ArgumentException！但至少您可以以易于单元测试的方式确定地构建URI。

组合URL的多个部分可能有点棘手。可以使用双参数构造函数Uri（baseUri、relativeUri），也可以使用Uri.TryCreate（）实用程序函数。

在任何一种情况下，您都可能会返回错误的结果，因为这些方法会不断截断第一个参数baseUri的相对部分，例如http://google.com/some/thing到http://google.com.

为了能够将多个部分合并为最终URL，可以复制以下两个函数：

    public static string Combine(params string[] parts)
    {
        if (parts == null || parts.Length == 0) return string.Empty;

        var urlBuilder = new StringBuilder();
        foreach (var part in parts)
        {
            var tempUrl = tryCreateRelativeOrAbsolute(part);
            urlBuilder.Append(tempUrl);
        }
        return VirtualPathUtility.RemoveTrailingSlash(urlBuilder.ToString());
    }

    private static string tryCreateRelativeOrAbsolute(string s)
    {
        System.Uri uri;
        System.Uri.TryCreate(s, UriKind.RelativeOrAbsolute, out uri);
        string tempUrl = VirtualPathUtility.AppendTrailingSlash(uri.ToString());
        return tempUrl;
    }

完整的代码和单元测试可以在https://uricombine.codeplex.com/SourceControl/latest#UriCombine/Uri.cs

我有单元测试来涵盖三种最常见的情况：

我结合了前面的所有答案：

    public static string UrlPathCombine(string path1, string path2)
    {
        path1 = path1.TrimEnd('/') + "/";
        path2 = path2.TrimStart('/');

        return Path.Combine(path1, path2)
            .Replace(Path.DirectorySeparatorChar, Path.AltDirectorySeparatorChar);
    }

    [TestMethod]
    public void TestUrl()
    {
        const string P1 = "http://msdn.microsoft.com/slash/library//";
        Assert.AreEqual("http://msdn.microsoft.com/slash/library/site.aspx", UrlPathCombine(P1, "//site.aspx"));

        var path = UrlPathCombine("Http://MyUrl.com/", "Images/Image.jpg");

        Assert.AreEqual(
            "Http://MyUrl.com/Images/Image.jpg",
            path);
    }