我知道这是一个老问题，但我遇到了同样的问题，上面的解决方案都没有真正解决我所面临的问题。我已经创建了一个字典，它将文件名与LastWriteTime映射。因此，如果文件不在字典中，将继续执行该进程，否则将检查最后一次修改时间是什么时候，如果与字典中的时间不同，则运行代码。

    Dictionary<string, DateTime> dateTimeDictionary = new Dictionary<string, DateTime>(); 

        private void OnChanged(object source, FileSystemEventArgs e)
            {
                if (!dateTimeDictionary.ContainsKey(e.FullPath) || (dateTimeDictionary.ContainsKey(e.FullPath) && System.IO.File.GetLastWriteTime(e.FullPath) != dateTimeDictionary[e.FullPath]))
                {
                    dateTimeDictionary[e.FullPath] = System.IO.File.GetLastWriteTime(e.FullPath);

                    //your code here
                }
            }

In my case need to get the last line of a text file that is inserted by other application, as soon as insertion is done. Here is my solution. When the first event is raised, i disable the watcher from raising others, then i call the timer TimeElapsedEvent because when my handle function OnChanged is called i need the size of the text file, but the size at that time is not the actual size, it is the size of the file imediatelly before the insertion. So i wait for a while to proceed with the right file size.

private FileSystemWatcher watcher = new FileSystemWatcher();
...
watcher.Path = "E:\\data";
watcher.NotifyFilter = NotifyFilters.LastWrite ;
watcher.Filter = "data.txt";
watcher.Changed += new FileSystemEventHandler(OnChanged);
watcher.EnableRaisingEvents = true;

...

private void OnChanged(object source, FileSystemEventArgs e)
   {
    System.Timers.Timer t = new System.Timers.Timer();
    try
    {
        watcher.Changed -= new FileSystemEventHandler(OnChanged);
        watcher.EnableRaisingEvents = false;

        t.Interval = 500;
        t.Elapsed += (sender, args) => t_Elapsed(sender, e);
        t.Start();
    }
    catch(Exception ex) {
        ;
    }
}

private void t_Elapsed(object sender, FileSystemEventArgs e) 
   {
    ((System.Timers.Timer)sender).Stop();
       //.. Do you stuff HERE ..
     watcher.Changed += new FileSystemEventHandler(OnChanged);
     watcher.EnableRaisingEvents = true;
}

这里有一个你可以尝试的新解决方案。很适合我。在已更改事件的事件处理程序中，以编程方式从设计器输出中删除处理程序(如果需要的话)，然后以编程方式将处理程序添加回来。例子:

public void fileSystemWatcher1_Changed( object sender, System.IO.FileSystemEventArgs e )
    {            
        fileSystemWatcher1.Changed -= new System.IO.FileSystemEventHandler( fileSystemWatcher1_Changed );
        MessageBox.Show( "File has been uploaded to destination", "Success!" );
        fileSystemWatcher1.Changed += new System.IO.FileSystemEventHandler( fileSystemWatcher1_Changed );
    }

代码可自定义禁用阻止第二个观察者升起的时间间隔，如果他们存在，则不阻止观察者:

    namespace Watcher
    {
        class Static
        {
            public static DateTime lastDomain { get; set; }
            public static string lastDomainStr { get; set; }
        }
        public partial class Form1 : Form
       {
            int minMs = 20;//time for blocking in ms
            public Form1()
            {
                InitializeComponent();
                Static.lastDomain = new DateTime(1970, 1, 1, 0, 0, 0);
                Static.lastDomainStr = "";  
                Start();
            }
             private void Start()//Start watcher
             {
                //...
                domain.Changed += new FileSystemEventHandler(Domain);
                domain.EnableRaisingEvents = true;
                //...you second unblocked watchers
                second.Changed += new FileSystemEventHandler(Second);
                second.EnableRaisingEvents = true;
             }
             private void Domain(object source, FileSystemEventArgs e)
             {
                if (now.Subtract(Static.lastDomain).TotalMilliseconds < minMs && Static.lastDomainStr == e.FullPath)return;
                 //...you code here
                 /* if you need form access
                 this.Invoke(new MethodInvoker(() =>{ textBox1.Text = "...";}));
                 */
                 Static.lastDomain = DateTime.Now;
                 Static.lastDomainStr = e.FullPath;
             }
             private void Second(object source, FileSystemEventArgs e)
             {
                  //...Second rised
             }
       }
    }

我用了n种更简单的方法。

布尔-如果正在进行某项操作，则为true。当它结束时，false。 在处理之前，将其添加到HashSet。这样我就不会重复元素了。 每隔30分钟，计时器的事件就会运行一次，如果没有作业正在执行，它就会清除列表(just hashset = new hashset)。

这个代码对我有用。

        private void OnChanged(object source, FileSystemEventArgs e)
    {

        string fullFilePath = e.FullPath.ToString();
        string fullURL = buildTheUrlFromStudyXML(fullFilePath);

        System.Diagnostics.Process.Start("iexplore", fullURL);

        Timer timer = new Timer();
        ((FileSystemWatcher)source).Changed -= new FileSystemEventHandler(OnChanged);
        timer.Interval = 1000;
        timer.Elapsed += new ElapsedEventHandler(t_Elapsed);
        timer.Start();
    }

    private void t_Elapsed(object sender, ElapsedEventArgs e)
    {
        ((Timer)sender).Stop();
        theWatcher.Changed += new FileSystemEventHandler(OnChanged);
    }