以读模式打开文件。以字符串格式读取文件。替换文本。关闭文件。再次以写模式打开文件。最后，将替换后的文本写入相同的文件。

try:
    with open("file_name", "r+") as text_file:
        texts = text_file.read()
        texts = texts.replace("to_replace", "replace_string")
    with open(file_name, "w") as text_file:
        text_file.write(texts)
except FileNotFoundError as f:
    print("Could not find the file you are trying to read.")

def findReplace(find, replace):

    import os 

    src = os.path.join(os.getcwd(), os.pardir) 

    for path, dirs, files in os.walk(os.path.abspath(src)):

        for name in files: 

            if name.endswith('.py'): 

                filepath = os.path.join(path, name)

                with open(filepath) as f: 

                    s = f.read()

                s = s.replace(find, replace) 

                with open(filepath, "w") as f:

                    f.write(s) 

我稍微修改了Jayram Singh的帖子，以替换每一个'!'字符转换为一个数字，我想在每个实例中增加这个数字。我想这对那些想要修改每行出现不止一次的字符并且想要迭代的人可能会有帮助。希望这能帮助到别人。PS-我在编码方面很新，所以如果我的帖子在任何方面都不合适，我很抱歉，但这对我来说是有效的。

f1 = open('file1.txt', 'r')
f2 = open('file2.txt', 'w')
n = 1  

# if word=='!'replace w/ [n] & increment n; else append same word to     
# file2

for line in f1:
    for word in line:
        if word == '!':
            f2.write(word.replace('!', f'[{n}]'))
            n += 1
        else:
            f2.write(word)
f1.close()
f2.close()

Fileinput已经支持就地编辑。在这种情况下，它将stdout重定向到文件:

#!/usr/bin/env python3
import fileinput

with fileinput.FileInput(filename, inplace=True, backup='.bak') as file:
    for line in file:
        print(line.replace(text_to_search, replacement_text), end='')

Besides the answers already mentioned, here is an explanation of why you have some random characters at the end: You are opening the file in r+ mode, not w mode. The key difference is that w mode clears the contents of the file as soon as you open it, whereas r+ doesn't. This means that if your file content is "123456789" and you write "www" to it, you get "www456789". It overwrites the characters with the new input, but leaves any remaining input untouched. You can clear a section of the file contents by using truncate(<startPosition>), but you are probably best off saving the updated file content to a string first, then doing truncate(0) and writing it all at once. Or you can use my library :D

以读模式打开文件。以字符串格式读取文件。替换文本。关闭文件。再次以写模式打开文件。最后，将替换后的文本写入相同的文件。

try:
    with open("file_name", "r+") as text_file:
        texts = text_file.read()
        texts = texts.replace("to_replace", "replace_string")
    with open(file_name, "w") as text_file:
        text_file.write(texts)
except FileNotFoundError as f:
    print("Could not find the file you are trying to read.")