使用re.subn可以对替换过程进行更多的控制，例如将单词分成两行，区分大小写的匹配。此外，它返回匹配的数量，如果没有找到字符串，可以使用这些匹配来避免浪费资源。

import re

file = # path to file

# they can be also raw string and regex
textToSearch = r'Ha.*O' # here an example with a regex
textToReplace = 'hallo'

# read and replace
with open(file, 'r') as fd:
    # sample case-insensitive find-and-replace
    text, counter = re.subn(textToSearch, textToReplace, fd.read(), re.I)

# check if there is at least a  match
if counter > 0:
    # edit the file
    with open(file, 'w') as fd:
        fd.write(text)

# summary result
print(f'{counter} occurence of "{textToSearch}" were replaced with "{textToReplace}".')

一些正则表达式:

添加re.I标志，re.IGNORECASE的缩写形式，用于不区分大小写的匹配 对于多行替换re.subn(r'\n*'.join(textToSearch)， textToReplace, fd.read()))，取决于数据也'\n{，1}'。注意，在这种情况下，textToSearch必须是纯字符串，而不是正则表达式!

像这样:

def find_and_replace(file, word, replacement):
  with open(file, 'r+') as f:
    text = f.read()
    f.write(text.replace(word, replacement))

Besides the answers already mentioned, here is an explanation of why you have some random characters at the end: You are opening the file in r+ mode, not w mode. The key difference is that w mode clears the contents of the file as soon as you open it, whereas r+ doesn't. This means that if your file content is "123456789" and you write "www" to it, you get "www456789". It overwrites the characters with the new input, but leaves any remaining input untouched. You can clear a section of the file contents by using truncate(<startPosition>), but you are probably best off saving the updated file content to a string first, then doing truncate(0) and writing it all at once. Or you can use my library :D

def findReplace(find, replace):

    import os 

    src = os.path.join(os.getcwd(), os.pardir) 

    for path, dirs, files in os.walk(os.path.abspath(src)):

        for name in files: 

            if name.endswith('.py'): 

                filepath = os.path.join(path, name)

                with open(filepath) as f: 

                    s = f.read()

                s = s.replace(find, replace) 

                with open(filepath, "w") as f:

                    f.write(s) 

我是这样做的:

#!/usr/bin/env python3

import fileinput
import os

Dir = input ("Source directory: ")
os.chdir(Dir)

Filelist = os.listdir()
print('File list: ',Filelist)

NomeFile = input ("Insert file name: ")

CarOr = input ("Text to search: ")

CarNew = input ("New text: ")

with fileinput.FileInput(NomeFile, inplace=True, backup='.bak') as file:
    for line in file:
        print(line.replace(CarOr, CarNew), end='')

file.close ()

我的变种，在整个文件中一次一个词。

我把它读进了记忆。

def replace_word(infile,old_word,new_word):
    if not os.path.isfile(infile):
        print ("Error on replace_word, not a regular file: "+infile)
        sys.exit(1)

    f1=open(infile,'r').read()
    f2=open(infile,'w')
    m=f1.replace(old_word,new_word)
    f2.write(m)