def findReplace(find, replace):

    import os 

    src = os.path.join(os.getcwd(), os.pardir) 

    for path, dirs, files in os.walk(os.path.abspath(src)):

        for name in files: 

            if name.endswith('.py'): 

                filepath = os.path.join(path, name)

                with open(filepath) as f: 

                    s = f.read()

                s = s.replace(find, replace) 

                with open(filepath, "w") as f:

                    f.write(s) 

Besides the answers already mentioned, here is an explanation of why you have some random characters at the end: You are opening the file in r+ mode, not w mode. The key difference is that w mode clears the contents of the file as soon as you open it, whereas r+ doesn't. This means that if your file content is "123456789" and you write "www" to it, you get "www456789". It overwrites the characters with the new input, but leaves any remaining input untouched. You can clear a section of the file contents by using truncate(<startPosition>), but you are probably best off saving the updated file content to a string first, then doing truncate(0) and writing it all at once. Or you can use my library :D

晚回答，但这是我用来在文本文件中查找和替换的:

with open("test.txt") as r:
  text = r.read().replace("THIS", "THAT")
with open("test.txt", "w") as w:
  w.write(text)

DEMO

你可以在python中使用sed、awk或grep(有一些限制)。这里有一个非常简单的例子。它在文件中把香蕉变成香蕉牙膏。你可以编辑和使用它。(我测试过了…注意:如果你在Windows下测试，你应该先安装sed命令并设置路径)

import os 
file="a.txt"
oldtext="Banana"
newtext=" BananaToothpaste"
os.system('sed -i "s/{}/{}/g" {}'.format(oldtext,newtext,file))
#print(f'sed -i "s/{oldtext}/{newtext}/g" {file}')
print('This command was applied:  sed -i "s/{}/{}/g" {}'.format(oldtext,newtext,file))

如果你想直接在文件上看到结果，应用:"type" for windows/ "cat" for linux:

####FOR WINDOWS:
os.popen("type " + file).read()
####FOR LINUX:
os.popen("cat " + file).read()

以读模式打开文件。以字符串格式读取文件。替换文本。关闭文件。再次以写模式打开文件。最后，将替换后的文本写入相同的文件。

try:
    with open("file_name", "r+") as text_file:
        texts = text_file.read()
        texts = texts.replace("to_replace", "replace_string")
    with open(file_name, "w") as text_file:
        text_file.write(texts)
except FileNotFoundError as f:
    print("Could not find the file you are trying to read.")

正如Jack Aidley发布的和J.F. Sebastian指出的那样，这个代码是行不通的:

 # Read in the file
filedata = None
with file = open('file.txt', 'r') :
  filedata = file.read()

# Replace the target string
filedata.replace('ram', 'abcd')

# Write the file out again
with file = open('file.txt', 'w') :
  file.write(filedata)`

但这段代码将工作(我已经测试过了):

f = open(filein,'r')
filedata = f.read()
f.close()

newdata = filedata.replace("old data","new data")

f = open(fileout,'w')
f.write(newdata)
f.close()

使用此方法，fileein和fileout可以是同一个文件，因为Python 3.3将在打开进行写入时覆盖该文件。