我把这句话建立在fj的精彩回答上:

import re

def multiple_replacer(*key_values):
    replace_dict = dict(key_values)
    replacement_function = lambda match: replace_dict[match.group(0)]
    pattern = re.compile("|".join([re.escape(k) for k, v in key_values]), re.M)
    return lambda string: pattern.sub(replacement_function, string)

def multiple_replace(string, *key_values):
    return multiple_replacer(*key_values)(string)

一针用法:

>>> replacements = (u"café", u"tea"), (u"tea", u"café"), (u"like", u"love")
>>> print multiple_replace(u"Do you like café? No, I prefer tea.", *replacements)
Do you love tea? No, I prefer café.

注意，由于替换只在一次传递中完成，“café”会变成“tea”，但不会变回“café”。

如果你需要做相同的替换多次，你可以很容易地创建一个替换函数:

>>> my_escaper = multiple_replacer(('"','\\"'), ('\t', '\\t'))
>>> many_many_strings = (u'This text will be escaped by "my_escaper"',
                       u'Does this work?\tYes it does',
                       u'And can we span\nmultiple lines?\t"Yes\twe\tcan!"')
>>> for line in many_many_strings:
...     print my_escaper(line)
... 
This text will be escaped by \"my_escaper\"
Does this work?\tYes it does
And can we span
multiple lines?\t\"Yes\twe\tcan!\"

改进:

将代码转换为函数 增加了多线支持 修正了逃跑的错误 容易创建一个函数，用于特定的多个替换

享受吧!: -)

下面是一个简短的例子，应该做的技巧与正则表达式:

import re

rep = {"condition1": "", "condition2": "text"} # define desired replacements here

# use these three lines to do the replacement
rep = dict((re.escape(k), v) for k, v in rep.iteritems()) 
#Python 3 renamed dict.iteritems to dict.items so use rep.items() for latest versions
pattern = re.compile("|".join(rep.keys()))
text = pattern.sub(lambda m: rep[re.escape(m.group(0))], text)

例如:

>>> pattern.sub(lambda m: rep[re.escape(m.group(0))], "(condition1) and --condition2--")
'() and --text--'

我今天也面临类似的问题，我不得不多次使用.replace()方法，但这对我来说感觉不太好。所以我做了这样的事情:

REPLACEMENTS = {'<': '&lt;', '>': '&gt;', '&': '&amp;'}

event_title = ''.join([REPLACEMENTS.get(c,c) for c in event['summary']])

我需要一个解决方案，其中字符串可以被替换为正则表达式， 例如，通过将多个空格字符替换为一个空格字符来帮助规范化长文本。根据其他人(包括MiniQuark和mmj)的一系列答案，我得出了以下结论:

def multiple_replace(string, reps, re_flags = 0):
    """ Transforms string, replacing keys from re_str_dict with values.
    reps: dictionary, or list of key-value pairs (to enforce ordering;
          earlier items have higher priority).
          Keys are used as regular expressions.
    re_flags: interpretation of regular expressions, such as re.DOTALL
    """
    if isinstance(reps, dict):
        reps = reps.items()
    pattern = re.compile("|".join("(?P<_%d>%s)" % (i, re_str[0])
                                  for i, re_str in enumerate(reps)),
                         re_flags)
    return pattern.sub(lambda x: reps[int(x.lastgroup[1:])][1], string)

它适用于其他答案中给出的例子，例如:

>>> multiple_replace("(condition1) and --condition2--",
...                  {"condition1": "", "condition2": "text"})
'() and --text--'

>>> multiple_replace('hello, world', {'hello' : 'goodbye', 'world' : 'earth'})
'goodbye, earth'

>>> multiple_replace("Do you like cafe? No, I prefer tea.",
...                  {'cafe': 'tea', 'tea': 'cafe', 'like': 'prefer'})
'Do you prefer tea? No, I prefer cafe.'

对我来说，最重要的是你也可以使用正则表达式，例如只替换整个单词，或规范化空白:

>>> s = "I don't want to change this name:\n  Philip II of Spain"
>>> re_str_dict = {r'\bI\b': 'You', r'[\n\t ]+': ' '}
>>> multiple_replace(s, re_str_dict)
"You don't want to change this name: Philip II of Spain"

如果你想使用字典键作为普通字符串， 你可以在调用multiple_replace之前转义这些，例如使用下面的函数:

def escape_keys(d):
    """ transform dictionary d by applying re.escape to the keys """
    return dict((re.escape(k), v) for k, v in d.items())

>>> multiple_replace(s, escape_keys(re_str_dict))
"I don't want to change this name:\n  Philip II of Spain"

下面的函数可以帮助在你的字典键中找到错误的正则表达式(因为来自multiple_replace的错误消息不是很明显):

def check_re_list(re_list):
    """ Checks if each regular expression in list is well-formed. """
    for i, e in enumerate(re_list):
        try:
            re.compile(e)
        except (TypeError, re.error):
            print("Invalid regular expression string "
                  "at position {}: '{}'".format(i, e))

>>> check_re_list(re_str_dict.keys())

请注意，它没有链接替换，而是同时执行它们。这使得它更有效率，而不会限制它能做什么。为了模仿链接的效果，你可能只需要添加更多的字符串替换对，并确保这些对的预期顺序:

>>> multiple_replace("button", {"but": "mut", "mutton": "lamb"})
'mutton'
>>> multiple_replace("button", [("button", "lamb"),
...                             ("but", "mut"), ("mutton", "lamb")])
'lamb'

在我的情况下，我需要一个简单的唯一键替换名称，所以我想到了这个:

a = 'This is a test string.'
b = {'i': 'I', 's': 'S'}
for x,y in b.items():
    a = a.replace(x, y)
>>> a
'ThIS IS a teSt StrIng.'

我不知道速度如何，但这是我日常的快速解决方法:

reduce(lambda a, b: a.replace(*b)
    , [('o','W'), ('t','X')] #iterable of pairs: (oldval, newval)
    , 'tomato' #The string from which to replace values
    )

．.． 但我喜欢上面的#1正则表达式答案。注意:如果一个新值是另一个值的子字符串，那么该操作是不可交换的。