我在运行单元测试时也遇到了这个问题。应用程序运行良好，没有错误。 在我的案例中，问题的原因是我关闭了测试项目的构建。 重新启用我的测试项目的构建解决了这些问题。

另一种情况是，有符号程序集的版本不正确。这不是这种疾病的正常症状，但这是我患病的情况

asp.net项目包含程序集A和程序集B, B是强命名的 程序集A使用Activator。CreateInstance加载程序集C(即没有对单独构建的C的引用) C是引用程序集B的较旧版本构建的

希望这能帮助到一些人，我花了很长时间才弄明白。

I had the same problem. I figured out that my assembly, which is loaded by the main program, had some references with "Copy Local" set to true. These local copies of references were looking for other references in the same folder, which did not exist because the "Copy Local" of other references was set to false. After the deletion of the "accidentally" copied references the error was gone because the main program was set to look for correct locations of references. Apparently the local copies of the references screwed up the sequence of calling because these local copies were used instead of the original ones present in the main program.

重要的信息是，出现此错误是因为缺少加载所需程序集的链接。

I got this error because I had a class in an assembly 'C' which was on version 4.5 of the framework, implementing an interface in assembly 'A' which was on version 4.5.1 of the framework and serving as the base class to assembly 'B' which was also on version 4.5.1 of the framework. The system threw the exception while trying to load assembly 'B'. Additionally, I had installed some nuget packages targeting .net 4.5.1 on all three assemblies. For some reason, even though the nuget references were not showing in assembly 'B', it was building successfully.

事实证明，真正的问题是程序集引用了包含接口的nuget包的不同版本，并且接口签名在不同版本之间发生了变化。

我在Visual Studio Pro 2008中看到了这一点，当时两个项目构建了具有相同名称的程序集，一个是类库SDF.dll，另一个是使用程序集名称sdf.exe引用程序库。 当我更改引用程序集的名称时，异常消失了

我也有这个错误，这是由任何CPU exe引用的任何CPU程序集，反过来引用x86程序集引起的。

异常抱怨MyApp中类的一个方法。实现(任何CPU)，它派生了MyApp。接口(任何CPU)，但在fuslogvw.exe中，我发现了一个隐藏的“试图从MyApp加载格式不正确的程序”异常。CommonTypes (x86)，两者都使用它。