也许我有一个解决Jan Koritak指出的矛盾的方法

SELECT CONCAT('SELECT ',
( SELECT GROUP_CONCAT(t.col)
FROM
(
    SELECT CASE
    WHEN COLUMN_NAME = 'eid' THEN NULL
    ELSE COLUMN_NAME
    END AS col 
    FROM INFORMATION_SCHEMA.COLUMNS 
    WHERE TABLE_NAME = 'employee' AND TABLE_SCHEMA = 'test'
) t
WHERE t.col IS NOT NULL) ,
' FROM employee' );

表:

SELECT table_name,column_name 
FROM INFORMATION_SCHEMA.COLUMNS 
WHERE TABLE_NAME = 'employee' AND TABLE_SCHEMA = 'test'

= = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = =

table_name  column_name
employee    eid
employee    name_eid
employee    sal

= = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = =

查询结果:

'SELECT name_eid,sal FROM employee'

Select *是一个SQL反模式。它不应该在生产代码中使用，原因有很多，包括:

它需要更长的时间来处理。当程序运行数百万次时，这些微小的部分就会产生影响。在缓慢的数据库中，这种缓慢是由这种类型的草率编码引起的，是最难进行性能调优的类型。

这意味着你发送的数据可能比你需要的多，这会导致服务器和网络瓶颈。如果您有一个内部连接，那么发送超过所需数据的可能性是100%。

这会导致维护问题，特别是当您添加了不想到处都看到的新列时。此外，如果您有一个新列，您可能需要对接口做一些事情，以确定对该列做什么。

它可以打破视图(我知道这在SQl server中是真的，在mysql中可能是真的，也可能不是真的)。

If someone is silly enough to rebuild the tables with the columns in a differnt order (which you shouldn't do but it happens all teh time), all sorts of code can break. Espcially code for an insert for example where suddenly you are putting the city into the address_3 field becasue without specifying, the database can only go on the order of the columns. This is bad enough when the data types change but worse when the swapped columns have the same datatype becasue you can go for sometime inserting bad data that is a mess to clean up. You need to care about data integrity.

如果在插入中使用它，如果在一个表中添加了新列，而在另一个表中没有添加，那么它将中断插入。

它可能会破坏触发器。触发问题可能很难诊断。

将所有这些与添加列名所花费的时间加起来(哎呀，你甚至可能有一个允许你拖拽列名的界面(我知道我在SQL Server中这样做，我打赌有一些方法可以做到这一点，你用一些工具来编写mysql查询)。让我们看看，“我可以引起维护问题，我可以引起性能问题，我可以引起数据完整性问题，但是嘿，我节省了5分钟的开发时间。”只需要填入你想要的具体列。

我也建议你读这本书: http://www.amazon.com/SQL-Antipatterns-Programming-Pragmatic-Programmers-ebook/dp/B00A376BB2/ref=sr_1_1?s=digital-text&ie=UTF8&qid=1389896688&sr=1-1&keywords=sql+antipatterns

视图在这种情况下工作得更好吗?

CREATE VIEW vwTable
as  
SELECT  
    col1  
    , col2  
    , col3  
    , col..  
    , col53  
FROM table

你可以:

SELECT column1, column2, column4 FROM table WHERE whatever

没有得到列3，尽管您可能在寻找一个更一般的解?

基于@Mahomedalid的答案，我做了一些改进，以支持“选择mysql中除某些列外的所有列”

SET @database    = 'database_name';
SET @tablename   = 'table_name';
SET @cols2delete = 'col1,col2,col3';

SET @sql = CONCAT(
'SELECT ', 
(
    SELECT GROUP_CONCAT( IF(FIND_IN_SET(COLUMN_NAME, @cols2delete), NULL, COLUMN_NAME ) )
    FROM INFORMATION_SCHEMA.COLUMNS WHERE TABLE_NAME = @tablename AND TABLE_SCHEMA = @database
), 
' FROM ',
@tablename);

SELECT @sql;

如果确实有很多cols，则使用此sql语句更改group_concat_max_len

SET @@group_concat_max_len = 2048;

我很晚才想出一个答案，坦率地说，这是我一直在做的事情，它比最好的答案要好100倍，我只希望有人能看到它。发现它很有用

    //create an array, we will call it here. 
    $here = array();
    //create an SQL query in order to get all of the column names
    $SQL = "SHOW COLUMNS FROM Table";
        //put all of the column names in the array
        foreach($conn->query($SQL) as $row) {
            $here[] = $row[0];
        }
    //now search through the array containing the column names for the name of the column, in this case i used the common ID field as an example
    $key = array_search('ID', $here);
    //now delete the entry
    unset($here[$key]);