不知道这有什么困难，做你正在做的，使用重载Bitmap构造函数来创建一个重新大小的图像，你唯一缺少的是转换回image数据类型:

public static Image resizeImage(Image imgToResize, Size size)
{
    return (Image)(new Bitmap(imgToResize, size));
}

yourImage = resizeImage(yourImage, new Size(50,50));

为什么不用System.Drawing.Image.GetThumbnailImage方法呢?

public Image GetThumbnailImage(
    int thumbWidth, 
    int thumbHeight, 
    Image.GetThumbnailImageAbort callback, 
    IntPtr callbackData)

例子:

Image originalImage = System.Drawing.Image.FromStream(inputStream, true, true);
Image resizedImage = originalImage.GetThumbnailImage(newWidth, (newWidth * originalImage.Height) / originalWidth, null, IntPtr.Zero);
resizedImage.Save(imagePath, ImageFormat.Png);

来源: http://msdn.microsoft.com/en-us/library/system.drawing.image.getthumbnailimage.aspx

在我做的应用程序中，有必要创建一个具有多个选项的函数。它相当大，但它可以调整图像的大小，可以保持纵横比，并可以切割边缘，只返回图像的中心:

/// <summary>
    /// Resize image with a directory as source
    /// </summary>
    /// <param name="OriginalFileLocation">Image location</param>
    /// <param name="heigth">new height</param>
    /// <param name="width">new width</param>
    /// <param name="keepAspectRatio">keep the aspect ratio</param>
    /// <param name="getCenter">return the center bit of the image</param>
    /// <returns>image with new dimentions</returns>
    public Image resizeImageFromFile(String OriginalFileLocation, int heigth, int width, Boolean keepAspectRatio, Boolean getCenter)
    {
        int newheigth = heigth;
        System.Drawing.Image FullsizeImage = System.Drawing.Image.FromFile(OriginalFileLocation);

        // Prevent using images internal thumbnail
        FullsizeImage.RotateFlip(System.Drawing.RotateFlipType.Rotate180FlipNone);
        FullsizeImage.RotateFlip(System.Drawing.RotateFlipType.Rotate180FlipNone);

        if (keepAspectRatio || getCenter)
        {
            int bmpY = 0;
            double resize = (double)FullsizeImage.Width / (double)width;//get the resize vector
            if (getCenter)
            {
                bmpY = (int)((FullsizeImage.Height - (heigth * resize)) / 2);// gives the Y value of the part that will be cut off, to show only the part in the center
                Rectangle section = new Rectangle(new Point(0, bmpY), new Size(FullsizeImage.Width, (int)(heigth * resize)));// create the section to cut of the original image
                //System.Console.WriteLine("the section that will be cut off: " + section.Size.ToString() + " the Y value is minimized by: " + bmpY);
                Bitmap orImg = new Bitmap((Bitmap)FullsizeImage);//for the correct effect convert image to bitmap.
                FullsizeImage.Dispose();//clear the original image
                using (Bitmap tempImg = new Bitmap(section.Width, section.Height))
                {
                    Graphics cutImg = Graphics.FromImage(tempImg);//              set the file to save the new image to.
                    cutImg.DrawImage(orImg, 0, 0, section, GraphicsUnit.Pixel);// cut the image and save it to tempImg
                    FullsizeImage = tempImg;//save the tempImg as FullsizeImage for resizing later
                    orImg.Dispose();
                    cutImg.Dispose();
                    return FullsizeImage.GetThumbnailImage(width, heigth, null, IntPtr.Zero);
                }
            }
            else newheigth = (int)(FullsizeImage.Height / resize);//  set the new heigth of the current image
        }//return the image resized to the given heigth and width
        return FullsizeImage.GetThumbnailImage(width, newheigth, null, IntPtr.Zero);
    }

为了更容易访问函数，可以添加一些重载函数:

/// <summary>
    /// Resize image with a directory as source
    /// </summary>
    /// <param name="OriginalFileLocation">Image location</param>
    /// <param name="heigth">new height</param>
    /// <param name="width">new width</param>
    /// <returns>image with new dimentions</returns>
    public Image resizeImageFromFile(String OriginalFileLocation, int heigth, int width)
    {
        return resizeImageFromFile(OriginalFileLocation, heigth, width, false, false);
    }

    /// <summary>
    /// Resize image with a directory as source
    /// </summary>
    /// <param name="OriginalFileLocation">Image location</param>
    /// <param name="heigth">new height</param>
    /// <param name="width">new width</param>
    /// <param name="keepAspectRatio">keep the aspect ratio</param>
    /// <returns>image with new dimentions</returns>
    public Image resizeImageFromFile(String OriginalFileLocation, int heigth, int width, Boolean keepAspectRatio)
    {
        return resizeImageFromFile(OriginalFileLocation, heigth, width, keepAspectRatio, false);
    }

现在是最后两个可选的布尔值。 像这样调用函数:

System.Drawing.Image ResizedImage = resizeImageFromFile(imageLocation, 800, 400, true, true);

如果你正在使用BitmapSource:

var resizedBitmap = new TransformedBitmap(
    bitmapSource,
    new ScaleTransform(scaleX, scaleY));

如果你想要更好的控制质量，首先运行这个:

RenderOptions.SetBitmapScalingMode(
    bitmapSource,
    BitmapScalingMode.HighQuality);

(默认为BitmapScalingMode。线性，相当于BitmapScalingMode.LowQuality。)

这个代码与上面的一个答案相同。但将透明像素转换为白色而不是黑色…谢谢:)

    public Image resizeImage(int newWidth, int newHeight, string stPhotoPath)
    {
        Image imgPhoto = Image.FromFile(stPhotoPath);

        int sourceWidth = imgPhoto.Width;
        int sourceHeight = imgPhoto.Height;

        //Consider vertical pics
        if (sourceWidth < sourceHeight)
        {
            int buff = newWidth;

            newWidth = newHeight;
            newHeight = buff;
        }

        int sourceX = 0, sourceY = 0, destX = 0, destY = 0;
        float nPercent = 0, nPercentW = 0, nPercentH = 0;

        nPercentW = ((float)newWidth / (float)sourceWidth);
        nPercentH = ((float)newHeight / (float)sourceHeight);
        if (nPercentH < nPercentW)
        {
            nPercent = nPercentH;
            destX = System.Convert.ToInt16((newWidth -
                      (sourceWidth * nPercent)) / 2);
        }
        else
        {
            nPercent = nPercentW;
            destY = System.Convert.ToInt16((newHeight -
                      (sourceHeight * nPercent)) / 2);
        }

        int destWidth = (int)(sourceWidth * nPercent);
        int destHeight = (int)(sourceHeight * nPercent);


        Bitmap bmPhoto = new Bitmap(newWidth, newHeight,
                      PixelFormat.Format24bppRgb);

        bmPhoto.SetResolution(imgPhoto.HorizontalResolution,
                     imgPhoto.VerticalResolution);

        Graphics grPhoto = Graphics.FromImage(bmPhoto);
        grPhoto.Clear(Color.White);
        grPhoto.InterpolationMode =
            System.Drawing.Drawing2D.InterpolationMode.HighQualityBicubic;

        grPhoto.DrawImage(imgPhoto,
            new Rectangle(destX, destY, destWidth, destHeight),
            new Rectangle(sourceX, sourceY, sourceWidth, sourceHeight),
            GraphicsUnit.Pixel);

        grPhoto.Dispose();
        imgPhoto.Dispose();

        return bmPhoto;
    }

public static Image resizeImage(Image image, int new_height, int new_width)
{
    Bitmap new_image = new Bitmap(new_width, new_height);
    Graphics g = Graphics.FromImage((Image)new_image );
    g.InterpolationMode = InterpolationMode.High;
    g.DrawImage(image, 0, 0, new_width, new_height);
    return new_image;
}