使用下面的函数和下面的例子来改变图像大小:

//Example : 
System.Net.Mime.MediaTypeNames.Image newImage = System.Net.Mime.MediaTypeNames.Image.FromFile("SampImag.jpg");
System.Net.Mime.MediaTypeNames.Image temImag = FormatImage(newImage, 100, 100);

//image size modification unction   
public static System.Net.Mime.MediaTypeNames.Image FormatImage(System.Net.Mime.MediaTypeNames.Image img, int outputWidth, int outputHeight)
{

    Bitmap outputImage = null;
    Graphics graphics = null;
    try
    {
         outputImage = new Bitmap(outputWidth, outputHeight, System.Drawing.Imaging.PixelFormat.Format16bppRgb555);
         graphics = Graphics.FromImage(outputImage);
         graphics.DrawImage(img, new Rectangle(0, 0, outputWidth, outputHeight),
         new Rectangle(0, 0, img.Width, img.Height), GraphicsUnit.Pixel);

         return outputImage;
     }
     catch (Exception ex)
     {
           return img;
     }
}

使用下面的函数和下面的例子来改变图像大小:

//Example : 
System.Net.Mime.MediaTypeNames.Image newImage = System.Net.Mime.MediaTypeNames.Image.FromFile("SampImag.jpg");
System.Net.Mime.MediaTypeNames.Image temImag = FormatImage(newImage, 100, 100);

//image size modification unction   
public static System.Net.Mime.MediaTypeNames.Image FormatImage(System.Net.Mime.MediaTypeNames.Image img, int outputWidth, int outputHeight)
{

    Bitmap outputImage = null;
    Graphics graphics = null;
    try
    {
         outputImage = new Bitmap(outputWidth, outputHeight, System.Drawing.Imaging.PixelFormat.Format16bppRgb555);
         graphics = Graphics.FromImage(outputImage);
         graphics.DrawImage(img, new Rectangle(0, 0, outputWidth, outputHeight),
         new Rectangle(0, 0, img.Width, img.Height), GraphicsUnit.Pixel);

         return outputImage;
     }
     catch (Exception ex)
     {
           return img;
     }
}

为什么不用System.Drawing.Image.GetThumbnailImage方法呢?

public Image GetThumbnailImage(
    int thumbWidth, 
    int thumbHeight, 
    Image.GetThumbnailImageAbort callback, 
    IntPtr callbackData)

例子:

Image originalImage = System.Drawing.Image.FromStream(inputStream, true, true);
Image resizedImage = originalImage.GetThumbnailImage(newWidth, (newWidth * originalImage.Height) / originalWidth, null, IntPtr.Zero);
resizedImage.Save(imagePath, ImageFormat.Png);

来源: http://msdn.microsoft.com/en-us/library/system.drawing.image.getthumbnailimage.aspx

注意:这将不适用于ASP。因为WebImage依赖于系统。Web，但在以前版本的ASP。我在Net中多次使用了这个片段，它很有用。

String ThumbfullPath = Path.GetFileNameWithoutExtension(file.FileName) + "80x80.jpg";
var ThumbfullPath2 = Path.Combine(ThumbfullPath, fileThumb);
using (MemoryStream stream = new MemoryStream(System.IO.File.ReadAllBytes(fullPath)))
{
      var thumbnail = new WebImage(stream).Resize(80, 80);
      thumbnail.Save(ThumbfullPath2, "jpg");
}

调整大小并保存图像以适应宽度和高度，就像画布保持图像成比例

using System;
using System.Drawing;
using System.Drawing.Drawing2D;
using System.Drawing.Imaging;
using System.IO;

namespace Infra.Files
{
    public static class GenerateThumb
    {
        /// <summary>
        /// Resize and save an image to fit under width and height like a canvas keeping things proportional
        /// </summary>
        /// <param name="originalImagePath"></param>
        /// <param name="thumbImagePath"></param>
        /// <param name="newWidth"></param>
        /// <param name="newHeight"></param>
        public static void GenerateThumbImage(string originalImagePath, string thumbImagePath, int newWidth, int newHeight)
        {
            Bitmap srcBmp = new Bitmap(originalImagePath);
            float ratio = 1;
            float minSize = Math.Min(newHeight, newHeight);

            if (srcBmp.Width > srcBmp.Height)
            {
                ratio = minSize / (float)srcBmp.Width;
            }
            else
            {
                ratio = minSize / (float)srcBmp.Height;
            }

            SizeF newSize = new SizeF(srcBmp.Width * ratio, srcBmp.Height * ratio);
            Bitmap target = new Bitmap((int)newSize.Width, (int)newSize.Height);

            using (Graphics graphics = Graphics.FromImage(target))
            {
                graphics.CompositingQuality = CompositingQuality.HighSpeed;
                graphics.InterpolationMode = InterpolationMode.HighQualityBicubic;
                graphics.CompositingMode = CompositingMode.SourceCopy;
                graphics.DrawImage(srcBmp, 0, 0, newSize.Width, newSize.Height);

                using (MemoryStream memoryStream = new MemoryStream())
                {
                    target.Save(thumbImagePath);
                }
            }
        }
    }
}

如果你正在使用BitmapSource:

var resizedBitmap = new TransformedBitmap(
    bitmapSource,
    new ScaleTransform(scaleX, scaleY));

如果你想要更好的控制质量，首先运行这个:

RenderOptions.SetBitmapScalingMode(
    bitmapSource,
    BitmapScalingMode.HighQuality);

(默认为BitmapScalingMode。线性，相当于BitmapScalingMode.LowQuality。)