注意:这将不适用于ASP。因为WebImage依赖于系统。Web，但在以前版本的ASP。我在Net中多次使用了这个片段，它很有用。

String ThumbfullPath = Path.GetFileNameWithoutExtension(file.FileName) + "80x80.jpg";
var ThumbfullPath2 = Path.Combine(ThumbfullPath, fileThumb);
using (MemoryStream stream = new MemoryStream(System.IO.File.ReadAllBytes(fullPath)))
{
      var thumbnail = new WebImage(stream).Resize(80, 80);
      thumbnail.Save(ThumbfullPath2, "jpg");
}

public static Image resizeImage(Image image, int new_height, int new_width)
{
    Bitmap new_image = new Bitmap(new_width, new_height);
    Graphics g = Graphics.FromImage((Image)new_image );
    g.InterpolationMode = InterpolationMode.High;
    g.DrawImage(image, 0, 0, new_width, new_height);
    return new_image;
}

在我做的应用程序中，有必要创建一个具有多个选项的函数。它相当大，但它可以调整图像的大小，可以保持纵横比，并可以切割边缘，只返回图像的中心:

/// <summary>
    /// Resize image with a directory as source
    /// </summary>
    /// <param name="OriginalFileLocation">Image location</param>
    /// <param name="heigth">new height</param>
    /// <param name="width">new width</param>
    /// <param name="keepAspectRatio">keep the aspect ratio</param>
    /// <param name="getCenter">return the center bit of the image</param>
    /// <returns>image with new dimentions</returns>
    public Image resizeImageFromFile(String OriginalFileLocation, int heigth, int width, Boolean keepAspectRatio, Boolean getCenter)
    {
        int newheigth = heigth;
        System.Drawing.Image FullsizeImage = System.Drawing.Image.FromFile(OriginalFileLocation);

        // Prevent using images internal thumbnail
        FullsizeImage.RotateFlip(System.Drawing.RotateFlipType.Rotate180FlipNone);
        FullsizeImage.RotateFlip(System.Drawing.RotateFlipType.Rotate180FlipNone);

        if (keepAspectRatio || getCenter)
        {
            int bmpY = 0;
            double resize = (double)FullsizeImage.Width / (double)width;//get the resize vector
            if (getCenter)
            {
                bmpY = (int)((FullsizeImage.Height - (heigth * resize)) / 2);// gives the Y value of the part that will be cut off, to show only the part in the center
                Rectangle section = new Rectangle(new Point(0, bmpY), new Size(FullsizeImage.Width, (int)(heigth * resize)));// create the section to cut of the original image
                //System.Console.WriteLine("the section that will be cut off: " + section.Size.ToString() + " the Y value is minimized by: " + bmpY);
                Bitmap orImg = new Bitmap((Bitmap)FullsizeImage);//for the correct effect convert image to bitmap.
                FullsizeImage.Dispose();//clear the original image
                using (Bitmap tempImg = new Bitmap(section.Width, section.Height))
                {
                    Graphics cutImg = Graphics.FromImage(tempImg);//              set the file to save the new image to.
                    cutImg.DrawImage(orImg, 0, 0, section, GraphicsUnit.Pixel);// cut the image and save it to tempImg
                    FullsizeImage = tempImg;//save the tempImg as FullsizeImage for resizing later
                    orImg.Dispose();
                    cutImg.Dispose();
                    return FullsizeImage.GetThumbnailImage(width, heigth, null, IntPtr.Zero);
                }
            }
            else newheigth = (int)(FullsizeImage.Height / resize);//  set the new heigth of the current image
        }//return the image resized to the given heigth and width
        return FullsizeImage.GetThumbnailImage(width, newheigth, null, IntPtr.Zero);
    }

为了更容易访问函数，可以添加一些重载函数:

/// <summary>
    /// Resize image with a directory as source
    /// </summary>
    /// <param name="OriginalFileLocation">Image location</param>
    /// <param name="heigth">new height</param>
    /// <param name="width">new width</param>
    /// <returns>image with new dimentions</returns>
    public Image resizeImageFromFile(String OriginalFileLocation, int heigth, int width)
    {
        return resizeImageFromFile(OriginalFileLocation, heigth, width, false, false);
    }

    /// <summary>
    /// Resize image with a directory as source
    /// </summary>
    /// <param name="OriginalFileLocation">Image location</param>
    /// <param name="heigth">new height</param>
    /// <param name="width">new width</param>
    /// <param name="keepAspectRatio">keep the aspect ratio</param>
    /// <returns>image with new dimentions</returns>
    public Image resizeImageFromFile(String OriginalFileLocation, int heigth, int width, Boolean keepAspectRatio)
    {
        return resizeImageFromFile(OriginalFileLocation, heigth, width, keepAspectRatio, false);
    }

现在是最后两个可选的布尔值。 像这样调用函数:

System.Drawing.Image ResizedImage = resizeImageFromFile(imageLocation, 800, 400, true, true);

如果你正在使用BitmapSource:

var resizedBitmap = new TransformedBitmap(
    bitmapSource,
    new ScaleTransform(scaleX, scaleY));

如果你想要更好的控制质量，首先运行这个:

RenderOptions.SetBitmapScalingMode(
    bitmapSource,
    BitmapScalingMode.HighQuality);

(默认为BitmapScalingMode。线性，相当于BitmapScalingMode.LowQuality。)

使用下面的函数和下面的例子来改变图像大小:

//Example : 
System.Net.Mime.MediaTypeNames.Image newImage = System.Net.Mime.MediaTypeNames.Image.FromFile("SampImag.jpg");
System.Net.Mime.MediaTypeNames.Image temImag = FormatImage(newImage, 100, 100);

//image size modification unction   
public static System.Net.Mime.MediaTypeNames.Image FormatImage(System.Net.Mime.MediaTypeNames.Image img, int outputWidth, int outputHeight)
{

    Bitmap outputImage = null;
    Graphics graphics = null;
    try
    {
         outputImage = new Bitmap(outputWidth, outputHeight, System.Drawing.Imaging.PixelFormat.Format16bppRgb555);
         graphics = Graphics.FromImage(outputImage);
         graphics.DrawImage(img, new Rectangle(0, 0, outputWidth, outputHeight),
         new Rectangle(0, 0, img.Width, img.Height), GraphicsUnit.Pixel);

         return outputImage;
     }
     catch (Exception ex)
     {
           return img;
     }
}

public string CreateThumbnail(int maxWidth, int maxHeight, string path)
{

    var image = System.Drawing.Image.FromFile(path);
    var ratioX = (double)maxWidth / image.Width;
    var ratioY = (double)maxHeight / image.Height;
    var ratio = Math.Min(ratioX, ratioY);
    var newWidth = (int)(image.Width * ratio);
    var newHeight = (int)(image.Height * ratio);
    var newImage = new Bitmap(newWidth, newHeight);
    Graphics thumbGraph = Graphics.FromImage(newImage);

    thumbGraph.CompositingQuality = CompositingQuality.HighQuality;
    thumbGraph.SmoothingMode = SmoothingMode.HighQuality;
    //thumbGraph.InterpolationMode = InterpolationMode.HighQualityBicubic;

    thumbGraph.DrawImage(image, 0, 0, newWidth, newHeight);
    image.Dispose();

    string fileRelativePath = "newsizeimages/" + maxWidth + Path.GetFileName(path);
    newImage.Save(Server.MapPath(fileRelativePath), newImage.RawFormat);
    return fileRelativePath;
}

点击这里http://bhupendrasinghsaini.blogspot.in/2014/07/resize-image-in-c.html