如果你想重用HttpClient，建议不要使用DefaultRequestHeaders，因为它们是用来发送每个请求的。

你可以试试这个:

var requestMessage = new HttpRequestMessage
    {
        Method = HttpMethod.Post,
        Content = new StringContent("...", Encoding.UTF8, "application/json"),
        RequestUri = new Uri("...")
    };

requestMessage.Headers.Authorization = new AuthenticationHeaderValue("Basic", 
    Convert.ToBase64String(System.Text.ASCIIEncoding.ASCII.GetBytes($"{user}:{password}")));

var response = await _httpClient.SendAsync(requestMessage);

request.DefaultRequestHeaders.Authorization = 
    new AuthenticationHeaderValue(
        "Basic", Convert.ToBase64String(
            System.Text.ASCIIEncoding.ASCII.GetBytes(
               $"{yourusername}:{yourpwd}")));

使用c# HttpClient设置基本身份验证。下面的代码为我工作。

   using (var client = new HttpClient())
        {
            var webUrl ="http://localhost/saleapi/api/";
            var uri = "api/sales";
            client.BaseAddress = new Uri(webUrl);
            client.DefaultRequestHeaders.Accept.Add(new MediaTypeWithQualityHeaderValue("application/json"));
            client.DefaultRequestHeaders.ConnectionClose = true;

            //Set Basic Auth
            var user = "username";
            var password = "password";
            var base64String =Convert.ToBase64String( Encoding.ASCII.GetBytes($"{user}:{password}"));
            client.DefaultRequestHeaders.Authorization = new AuthenticationHeaderValue("Basic",base64String);

            var result = await client.PostAsJsonAsync(uri, model);
            return result;
        }

我在设置不记名代币

httpClient.DefaultRequestHeaders.Authorization = new AuthenticationHeaderValue("Bearer", token);

它在一个端点上起作用，但在另一个端点上不起作用。问题是我在"持票人"上用了小写b。改变后，现在它工作的两个api的我正在击中。如果你甚至不把它看作是寻找针的干草堆之一，这是一件很容易错过的事情。

一定要有“持票人”，要有资本。

在net .core中，您可以使用Identity Server 4

var client = new HttpClient();
client.SetBasicAuthentication(userName, password);

or

var client = new HttpClient();
client.SetBearerToken(token);

参见https://github.com/IdentityModel/IdentityModel/blob/main/src/Client/Extensions/AuthorizationHeaderExtensions.cs

方法是这样的，

httpClient.DefaultRequestHeaders.Authorization =
    new AuthenticationHeaderValue("Bearer", "Your Oauth token");