我最近不得不处理这个问题——另一种方法是使用WebClient是可继承的这一事实，并从那里改变底层的WebRequest:

http://msdn.microsoft.com/en-us/library/system.net.webclient.getwebrequest (VS.80) . aspx

我更喜欢c#，但如果你坚持使用VB，结果将是这样的:

Public Class BigWebClient
    Inherits WebClient
    Protected Overrides Function GetWebRequest(ByVal address As System.Uri) As System.Net.WebRequest
        Dim x As WebRequest = MyBase.GetWebRequest(address)
        x.Timeout = 60 * 60 * 1000
        Return x
    End Function
End Class

'Use BigWebClient here instead of WebClient

对于我来说，下面的作品(主要是受到以下所有回答的启发)，我从Elad的回答开始，修改/简化事情以符合我的需要(删除不是文件形式输入，只有一个文件，……)

希望它能帮助到一些人:)

(PS:我知道异常处理没有实现，并且假设它是在一个类中编写的，所以我可能需要一些集成工作…)

private void uploadFile()
    {
        Random rand = new Random();
        string boundary = "----boundary" + rand.Next().ToString();
        Stream data_stream;
        byte[] header = System.Text.Encoding.ASCII.GetBytes("\r\n--" + boundary + "\r\nContent-Disposition: form-data; name=\"file_path\"; filename=\"" + System.IO.Path.GetFileName(this.file) + "\"\r\nContent-Type: application/octet-stream\r\n\r\n");
        byte[] trailer = System.Text.Encoding.ASCII.GetBytes("\r\n--" + boundary + "--\r\n");

        // Do the request
        HttpWebRequest request = (HttpWebRequest)WebRequest.Create(MBF_URL);
        request.UserAgent = "My Toolbox";
        request.Method = "POST";
        request.KeepAlive = true;
        request.ContentType = "multipart/form-data; boundary=" + boundary;
        data_stream = request.GetRequestStream();
        data_stream.Write(header, 0, header.Length);
        byte[] file_bytes = System.IO.File.ReadAllBytes(this.file);
        data_stream.Write(file_bytes, 0, file_bytes.Length);
        data_stream.Write(trailer, 0, trailer.Length);
        data_stream.Close();

        // Read the response
        WebResponse response = request.GetResponse();
        data_stream = response.GetResponseStream();
        StreamReader reader = new StreamReader(data_stream);
        this.url = reader.ReadToEnd();

        if (this.url == "") { this.url = "No response :("; }

        reader.Close();
        data_stream.Close();
        response.Close();
    }

采用上面的代码并修复，因为它抛出内部服务器错误500。\r\n的位置和空格等存在一些问题。应用内存流重构，直接写入请求流。结果如下:

    public static void HttpUploadFile(string url, string file, string paramName, string contentType, NameValueCollection nvc) {
        log.Debug(string.Format("Uploading {0} to {1}", file, url));
        string boundary = "---------------------------" + DateTime.Now.Ticks.ToString("x");
        byte[] boundarybytes = System.Text.Encoding.ASCII.GetBytes("\r\n--" + boundary + "\r\n");

        HttpWebRequest wr = (HttpWebRequest)WebRequest.Create(url);
        wr.ContentType = "multipart/form-data; boundary=" + boundary;
        wr.Method = "POST";
        wr.KeepAlive = true;
        wr.Credentials = System.Net.CredentialCache.DefaultCredentials;

        Stream rs = wr.GetRequestStream();

        string formdataTemplate = "Content-Disposition: form-data; name=\"{0}\"\r\n\r\n{1}";
        foreach (string key in nvc.Keys)
        {
            rs.Write(boundarybytes, 0, boundarybytes.Length);
            string formitem = string.Format(formdataTemplate, key, nvc[key]);
            byte[] formitembytes = System.Text.Encoding.UTF8.GetBytes(formitem);
            rs.Write(formitembytes, 0, formitembytes.Length);
        }
        rs.Write(boundarybytes, 0, boundarybytes.Length);

        string headerTemplate = "Content-Disposition: form-data; name=\"{0}\"; filename=\"{1}\"\r\nContent-Type: {2}\r\n\r\n";
        string header = string.Format(headerTemplate, paramName, file, contentType);
        byte[] headerbytes = System.Text.Encoding.UTF8.GetBytes(header);
        rs.Write(headerbytes, 0, headerbytes.Length);

        FileStream fileStream = new FileStream(file, FileMode.Open, FileAccess.Read);
        byte[] buffer = new byte[4096];
        int bytesRead = 0;
        while ((bytesRead = fileStream.Read(buffer, 0, buffer.Length)) != 0) {
            rs.Write(buffer, 0, bytesRead);
        }
        fileStream.Close();

        byte[] trailer = System.Text.Encoding.ASCII.GetBytes("\r\n--" + boundary + "--\r\n");
        rs.Write(trailer, 0, trailer.Length);
        rs.Close();

        WebResponse wresp = null;
        try {
            wresp = wr.GetResponse();
            Stream stream2 = wresp.GetResponseStream();
            StreamReader reader2 = new StreamReader(stream2);
            log.Debug(string.Format("File uploaded, server response is: {0}", reader2.ReadToEnd()));
        } catch(Exception ex) {
            log.Error("Error uploading file", ex);
            if(wresp != null) {
                wresp.Close();
                wresp = null;
            }
        } finally {
            wr = null;
        }
    }

以及示例用法:

    NameValueCollection nvc = new NameValueCollection();
    nvc.Add("id", "TTR");
    nvc.Add("btn-submit-photo", "Upload");
    HttpUploadFile("http://your.server.com/upload", 
         @"C:\test\test.jpg", "file", "image/jpeg", nvc);

可以扩展它来处理多个文件，或者对每个文件多次调用它。但它适合你的需要。

修改了@CristianRomanescu代码，以使用内存流，接受文件作为字节数组，允许空nvc，返回请求响应和使用授权头。使用Web Api 2测试代码。

private string HttpUploadFile(string url, byte[] file, string fileName, string paramName, string contentType, NameValueCollection nvc, string authorizationHeader)
{
    string boundary = "---------------------------" + DateTime.Now.Ticks.ToString("x");
    byte[] boundarybytes = System.Text.Encoding.ASCII.GetBytes("\r\n--" + boundary + "\r\n");

    HttpWebRequest wr = (HttpWebRequest)WebRequest.Create(url);
    wr.ContentType = "multipart/form-data; boundary=" + boundary;
    wr.Method = "POST";
    wr.Headers.Add("Authorization", authorizationHeader);
    wr.KeepAlive = true;

    Stream rs = wr.GetRequestStream();

    string formdataTemplate = "Content-Disposition: form-data; name=\"{0}\"\r\n\r\n{1}";
    if (nvc != null)
    {
        foreach (string key in nvc.Keys)
        {
            rs.Write(boundarybytes, 0, boundarybytes.Length);
            string formitem = string.Format(formdataTemplate, key, nvc[key]);
            byte[] formitembytes = System.Text.Encoding.UTF8.GetBytes(formitem);
            rs.Write(formitembytes, 0, formitembytes.Length);
        }
    }

    rs.Write(boundarybytes, 0, boundarybytes.Length);

    string headerTemplate = "Content-Disposition: form-data; name=\"{0}\"; filename=\"{1}\"\r\nContent-Type: {2}\r\n\r\n";
    string header = string.Format(headerTemplate, paramName, fileName, contentType);
    byte[] headerbytes = System.Text.Encoding.UTF8.GetBytes(header);
    rs.Write(headerbytes, 0, headerbytes.Length);

    rs.Write(file, 0, file.Length);

    byte[] trailer = System.Text.Encoding.ASCII.GetBytes("\r\n--" + boundary + "--\r\n");
    rs.Write(trailer, 0, trailer.Length);
    rs.Close();

    WebResponse wresp = null;
    try
    {
        wresp = wr.GetResponse();
        Stream stream2 = wresp.GetResponseStream();
        StreamReader reader2 = new StreamReader(stream2);
        var response = reader2.ReadToEnd();
        return response;
    }
    catch (Exception ex)
    {
        if (wresp != null)
        {
            wresp.Close();
            wresp = null;
        }
        return null;
    }
    finally
    {
        wr = null;
    }
}

Testcode:

[HttpPost]
[Route("postformdata")]
public IHttpActionResult PostFormData()
{
    // Check if the request contains multipart/form-data.
    if (!Request.Content.IsMimeMultipartContent())
    {
        throw new HttpResponseException(HttpStatusCode.UnsupportedMediaType);
    }

    var provider = new MultipartMemoryStreamProvider();

    try
    {
        // Read the form data.
        var result = Request.Content.ReadAsMultipartAsync(provider).Result;
        string response = "";
        // This illustrates how to get the file names.
        foreach (var file in provider.Contents)
        {
            var fileName = file.Headers.ContentDisposition.FileName.Trim('\"');
            var buffer =  file.ReadAsByteArrayAsync().Result;
            response = HttpUploadFile("https://localhost/api/v1/createfromfile", buffer, fileName, "file", "application/pdf", null, "AuthorizationKey");
        }
        return Ok(response);
    }
    catch (System.Exception e)
    {
        return InternalServerError();
    }
}

我的ASP。NET上传常见问题解答中有一篇关于这方面的文章，有示例代码:使用HttpWebRequest/WebClient的RFC 1867 POST请求上传文件。此代码不将文件加载到内存中(与上面的代码相反)，支持多个文件，并支持表单值、设置凭据和cookie等。

编辑:看起来好像是Axosoft把这个页面删除了。谢谢你的家伙。

它仍然可以通过archive.org访问。

我知道这可能有点晚了，但我一直在寻找同样的解决方案。我从一位微软代表那里找到了以下回复

private void UploadFilesToRemoteUrl(string url, string[] files, string logpath, NameValueCollection nvc)
{

    long length = 0;
    string boundary = "----------------------------" +
    DateTime.Now.Ticks.ToString("x");


    HttpWebRequest httpWebRequest2 = (HttpWebRequest)WebRequest.Create(url);
    httpWebRequest2.ContentType = "multipart/form-data; boundary=" +
    boundary;
    httpWebRequest2.Method = "POST";
    httpWebRequest2.KeepAlive = true;
    httpWebRequest2.Credentials = System.Net.CredentialCache.DefaultCredentials;



    Stream memStream = new System.IO.MemoryStream();
    byte[] boundarybytes = System.Text.Encoding.ASCII.GetBytes("\r\n--" + boundary + "\r\n");


    string formdataTemplate = "\r\n--" + boundary + "\r\nContent-Disposition: form-data; name=\"{0}\";\r\n\r\n{1}";

    foreach(string key in nvc.Keys)
    {
        string formitem = string.Format(formdataTemplate, key, nvc[key]);
        byte[] formitembytes = System.Text.Encoding.UTF8.GetBytes(formitem);
        memStream.Write(formitembytes, 0, formitembytes.Length);
    }


    memStream.Write(boundarybytes,0,boundarybytes.Length);

    string headerTemplate = "Content-Disposition: form-data; name=\"{0}\"; filename=\"{1}\"\r\n Content-Type: application/octet-stream\r\n\r\n";

    for(int i=0;i<files.Length;i++)
    {

        string header = string.Format(headerTemplate,"file"+i,files[i]);
        byte[] headerbytes = System.Text.Encoding.UTF8.GetBytes(header);
        memStream.Write(headerbytes,0,headerbytes.Length);


        FileStream fileStream = new FileStream(files[i], FileMode.Open,
        FileAccess.Read);
        byte[] buffer = new byte[1024];

        int bytesRead = 0;

        while ( (bytesRead = fileStream.Read(buffer, 0, buffer.Length)) != 0 )
        {
            memStream.Write(buffer, 0, bytesRead);
        }


        memStream.Write(boundarybytes,0,boundarybytes.Length);


        fileStream.Close();
    }

    httpWebRequest2.ContentLength = memStream.Length;
    Stream requestStream = httpWebRequest2.GetRequestStream();

    memStream.Position = 0;
    byte[] tempBuffer = new byte[memStream.Length];
    memStream.Read(tempBuffer,0,tempBuffer.Length);
    memStream.Close();
    requestStream.Write(tempBuffer,0,tempBuffer.Length );
    requestStream.Close();


    WebResponse webResponse2 = httpWebRequest2.GetResponse();

    Stream stream2 = webResponse2.GetResponseStream();
    StreamReader reader2 = new StreamReader(stream2);

    webResponse2.Close();
    httpWebRequest2 = null;
    webResponse2 = null;

}