我很长一段时间都在纠结这个问题，我想分享我的解决方案。

这将为您提供一个UILabel，它将自动将文本缩小到0.5个刻度，并将文本垂直居中。故事板/IB中也提供了这些选项。

[labelObject setMinimumScaleFactor:0.5];
[labelObject setBaselineAdjustment:UIBaselineAdjustmentAlignCenters];

在发布的所有其他解决方案的基础上，我创建了一个简单的小UILabel子类，在设置其对齐属性时将为您处理垂直对齐。这还将在方向更改时更新标签，将高度约束到文本，并将标签的宽度保持在其原始大小。

.h

@interface VAlignLabel : UILabel
@property (nonatomic, assign) WBZVerticalAlignment alignment;
@end


.m

 -(void)setAlignment:(WBZVerticalAlignment)alignment{

    _alignment = alignment;

    CGSize s = [self.text sizeWithFont:self.font constrainedToSize:CGSizeMake(self.frame.size.width, 9999) lineBreakMode:NSLineBreakByWordWrapping];

    switch (_alignment)
    {
        case wbzLabelAlignmentVerticallyTop:
            self.frame = CGRectMake(self.frame.origin.x, self.frame.origin.y, self.frame.size.width, s.height);
            break;
        case wbzLabelAlignmentVerticallyMiddle:
            self.frame = CGRectMake(self.frame.origin.x, self.frame.origin.y + (self.frame.size.height - s.height)/2, self.frame.size.width, s.height);
            break;
        case wbzLabelAlignmentVerticallyBottom:
            self.frame = CGRectMake(self.frame.origin.x, self.frame.origin.y + (self.frame.size.height - s.height), self.frame.size.width, s.height);
            break;
        default:
            break;
    }
}

-(void)layoutSubviews{
    [self setAlignment:self.alignment];
}

子类UILabel并约束绘图矩形，如下所示：

- (void)drawTextInRect:(CGRect)rect
{
    CGSize sizeThatFits = [self sizeThatFits:rect.size];
    rect.size.height = MIN(rect.size.height, sizeThatFits.height);

    [super drawTextInRect:rect];
}

我尝试了涉及换行填充的解决方案，在某些情况下遇到了错误的行为。根据我的经验，如上所述约束绘图矩形比使用numberOfLines更容易。

P.S.你可以想象一下这样轻松地支持UIViewContentMode：

- (void)drawTextInRect:(CGRect)rect
{
    CGSize sizeThatFits = [self sizeThatFits:rect.size];

    if (self.contentMode == UIViewContentModeTop) {
        rect.size.height = MIN(rect.size.height, sizeThatFits.height);
    }
    else if (self.contentMode == UIViewContentModeBottom) {
        rect.origin.y = MAX(0, rect.size.height - sizeThatFits.height);
        rect.size.height = MIN(rect.size.height, sizeThatFits.height);
    }

    [super drawTextInRect:rect];
}

Swift 2.0版本：

在空Swift文件中生成常量枚举值。

//  AppRef.swift

import UIKit
import Foundation

enum UILabelTextPositions : String {

 case VERTICAL_ALIGNMENT_TOP = "VerticalAlignmentTop"
 case VERTICAL_ALIGNMENT_MIDDLE = "VerticalAlignmentMiddle"
 case VERTICAL_ALIGNMENT_BOTTOM = "VerticalAlignmentBottom"

}

使用UILabel扩展：

创建一个空的Swift类并命名它

//  AppExtensions.swift

import Foundation
import UIKit

extension UILabel{ 
 func makeLabelTextPosition (sampleLabel :UILabel?, positionIdentifier : String) -> UILabel
 {
  let rect = sampleLabel!.textRectForBounds(bounds, limitedToNumberOfLines: 0)

  switch positionIdentifier
  {
  case "VerticalAlignmentTop":
   sampleLabel!.frame = CGRectMake(bounds.origin.x+5, bounds.origin.y, rect.size.width, rect.size.height)
   break;

  case "VerticalAlignmentMiddle":
   sampleLabel!.frame = CGRectMake(bounds.origin.x+5,bounds.origin.y + (bounds.size.height - rect.size.height) / 2,
    rect.size.width, rect.size.height);
   break;

  case "VerticalAlignmentBottom":
   sampleLabel!.frame = CGRectMake(bounds.origin.x+5, bounds.origin.y + (bounds.size.height - rect.size.height),rect.size.width, rect.size.height);
   break;

  default:
   sampleLabel!.frame = bounds;
   break;
  }
  return sampleLabel!

 }
}

用法：

myMessageLabel.makeLabelTextPosition(messageLabel, positionIdentifier: UILabelTextPositions.VERTICAL_ALIGNMENT_TOP.rawValue)

yourLabel.baselineAdjustment = UIBaselineAdjustmentAlignCenters;

参考扩展解决方案：

for(int i=1; i< newLinesToPad; i++) 
    self.text = [self.text stringByAppendingString:@"\n"];

应替换为

for(int i=0; i<newLinesToPad; i++)
    self.text = [self.text stringByAppendingString:@"\n "];

每增加一行换行符都需要额外的空间，因为iPhone UILabels的尾部回车符似乎被忽略了：(

同样，alignBottom也应该用@“\n@%”代替“\n@”进行更新（对于周期初始化，也必须用“for（int i=0…”替换）。

以下扩展适用于我：

// -- file: UILabel+VerticalAlign.h
#pragma mark VerticalAlign
@interface UILabel (VerticalAlign)
- (void)alignTop;
- (void)alignBottom;
@end

// -- file: UILabel+VerticalAlign.m
@implementation UILabel (VerticalAlign)
- (void)alignTop {
    CGSize fontSize = [self.text sizeWithFont:self.font];
    double finalHeight = fontSize.height * self.numberOfLines;
    double finalWidth = self.frame.size.width;    //expected width of label
    CGSize theStringSize = [self.text sizeWithFont:self.font constrainedToSize:CGSizeMake(finalWidth, finalHeight) lineBreakMode:self.lineBreakMode];
    int newLinesToPad = (finalHeight  - theStringSize.height) / fontSize.height;
    for(int i=0; i<newLinesToPad; i++)
        self.text = [self.text stringByAppendingString:@"\n "];
}

- (void)alignBottom {
    CGSize fontSize = [self.text sizeWithFont:self.font];
    double finalHeight = fontSize.height * self.numberOfLines;
    double finalWidth = self.frame.size.width;    //expected width of label
    CGSize theStringSize = [self.text sizeWithFont:self.font constrainedToSize:CGSizeMake(finalWidth, finalHeight) lineBreakMode:self.lineBreakMode];
    int newLinesToPad = (finalHeight  - theStringSize.height) / fontSize.height;
    for(int i=0; i<newLinesToPad; i++)
        self.text = [NSString stringWithFormat:@" \n%@",self.text];
}
@end

然后调用[yourLabel alignTop]；或[yourLabel alignBottom]；在每次标签文本分配后。