这里有一个函数可以对任意数量的列执行此操作。

def mean_first(df):
    ncols = df.shape[1]        # Get the number of columns
    index = list(range(ncols)) # Create an index to reorder the columns
    index.insert(0,ncols)      # This puts the last column at the front
    return(df.assign(mean=df.mean(1)).iloc[:,index]) # new df with last column (mean) first

这里有一个函数可以对任意数量的列执行此操作。

def mean_first(df):
    ncols = df.shape[1]        # Get the number of columns
    index = list(range(ncols)) # Create an index to reorder the columns
    index.insert(0,ncols)      # This puts the last column at the front
    return(df.assign(mean=df.mean(1)).iloc[:,index]) # new df with last column (mean) first

要根据其他列的名称将现有列设置为右侧/左侧，请执行以下操作：

def df_move_column(df, col_to_move, col_left_of_destiny="", right_of_col_bool=True):
    cols = list(df.columns.values)
    index_max = len(cols) - 1

    if not right_of_col_bool:
        # set left of a column "c", is like putting right of column previous to "c"
        # ... except if left of 1st column, then recursive call to set rest right to it
        aux = cols.index(col_left_of_destiny)
        if not aux:
            for g in [x for x in cols[::-1] if x != col_to_move]:
                df = df_move_column(
                        df, 
                        col_to_move=g, 
                        col_left_of_destiny=col_to_move
                        )
            return df
        col_left_of_destiny = cols[aux - 1]

    index_old = cols.index(col_to_move)
    index_new = 0
    if len(col_left_of_destiny):
        index_new = cols.index(col_left_of_destiny) + 1

    if index_old == index_new:
        return df

    if index_new < index_old:
        index_new = np.min([index_new, index_max])
        cols = (
            cols[:index_new]
            + [cols[index_old]]
            + cols[index_new:index_old]
            + cols[index_old + 1 :]
        )
    else:
        cols = (
            cols[:index_old]
            + cols[index_old + 1 : index_new]
            + [cols[index_old]]
            + cols[index_new:]
        )

    df = df[cols]
    return df

E.g.

cols = list("ABCD")
df2 = pd.DataFrame(np.arange(4)[np.newaxis, :], columns=cols)
for k in cols:
    print(30 * "-")
    for g in [x for x in cols if x != k]:
        df_new = df_move_column(df2, k, g)
        print(f"{k} after {g}:  {df_new.columns.values}")
for k in cols:
    print(30 * "-")
    for g in [x for x in cols if x != k]:
        df_new = df_move_column(df2, k, g, right_of_col_bool=False)
        print(f"{k} before {g}:  {df_new.columns.values}")

输出：

我想到了和Dmitriy Work一样的答案，显然是最简单的：

df["mean"] = df.mean(1)
l =  list(np.arange(0,len(df.columns) -1 ))
l.insert(0,-1)
df.iloc[:,l]

一种简单的方法是用列列表重新分配数据帧，根据需要重新排列。

这就是你现在拥有的：

In [6]: df
Out[6]:
          0         1         2         3         4      mean
0  0.445598  0.173835  0.343415  0.682252  0.582616  0.445543
1  0.881592  0.696942  0.702232  0.696724  0.373551  0.670208
2  0.662527  0.955193  0.131016  0.609548  0.804694  0.632596
3  0.260919  0.783467  0.593433  0.033426  0.512019  0.436653
4  0.131842  0.799367  0.182828  0.683330  0.019485  0.363371
5  0.498784  0.873495  0.383811  0.699289  0.480447  0.587165
6  0.388771  0.395757  0.745237  0.628406  0.784473  0.588529
7  0.147986  0.459451  0.310961  0.706435  0.100914  0.345149
8  0.394947  0.863494  0.585030  0.565944  0.356561  0.553195
9  0.689260  0.865243  0.136481  0.386582  0.730399  0.561593

In [7]: cols = df.columns.tolist()

In [8]: cols
Out[8]: [0L, 1L, 2L, 3L, 4L, 'mean']

按任意方式重新排列列。这是我将最后一个元素移动到第一个位置的方式：

In [12]: cols = cols[-1:] + cols[:-1]

In [13]: cols
Out[13]: ['mean', 0L, 1L, 2L, 3L, 4L]

然后重新排序数据帧，如下所示：

In [16]: df = df[cols]  #    OR    df = df.ix[:, cols]

In [17]: df
Out[17]:
       mean         0         1         2         3         4
0  0.445543  0.445598  0.173835  0.343415  0.682252  0.582616
1  0.670208  0.881592  0.696942  0.702232  0.696724  0.373551
2  0.632596  0.662527  0.955193  0.131016  0.609548  0.804694
3  0.436653  0.260919  0.783467  0.593433  0.033426  0.512019
4  0.363371  0.131842  0.799367  0.182828  0.683330  0.019485
5  0.587165  0.498784  0.873495  0.383811  0.699289  0.480447
6  0.588529  0.388771  0.395757  0.745237  0.628406  0.784473
7  0.345149  0.147986  0.459451  0.310961  0.706435  0.100914
8  0.553195  0.394947  0.863494  0.585030  0.565944  0.356561
9  0.561593  0.689260  0.865243  0.136481  0.386582  0.730399

另一种选择是使用set_index（）方法，后跟reset_index（）。请注意，我们首先pop（）将要移动到数据帧前面的列，以便在重置索引时避免名称冲突：

df.set_index(df.pop('column_name'), inplace=True)
df.reset_index(inplace=True)

有关详细信息，请参阅How to change the order of dataframe columns in panda。