您可以使用可用于两个轴的重新索引：

df
#           0         1         2         3         4      mean
# 0  0.943825  0.202490  0.071908  0.452985  0.678397  0.469921
# 1  0.745569  0.103029  0.268984  0.663710  0.037813  0.363821
# 2  0.693016  0.621525  0.031589  0.956703  0.118434  0.484254
# 3  0.284922  0.527293  0.791596  0.243768  0.629102  0.495336
# 4  0.354870  0.113014  0.326395  0.656415  0.172445  0.324628
# 5  0.815584  0.532382  0.195437  0.829670  0.019001  0.478415
# 6  0.944587  0.068690  0.811771  0.006846  0.698785  0.506136
# 7  0.595077  0.437571  0.023520  0.772187  0.862554  0.538182
# 8  0.700771  0.413958  0.097996  0.355228  0.656919  0.444974
# 9  0.263138  0.906283  0.121386  0.624336  0.859904  0.555009

df.reindex(['mean', *range(5)], axis=1)

#        mean         0         1         2         3         4
# 0  0.469921  0.943825  0.202490  0.071908  0.452985  0.678397
# 1  0.363821  0.745569  0.103029  0.268984  0.663710  0.037813
# 2  0.484254  0.693016  0.621525  0.031589  0.956703  0.118434
# 3  0.495336  0.284922  0.527293  0.791596  0.243768  0.629102
# 4  0.324628  0.354870  0.113014  0.326395  0.656415  0.172445
# 5  0.478415  0.815584  0.532382  0.195437  0.829670  0.019001
# 6  0.506136  0.944587  0.068690  0.811771  0.006846  0.698785
# 7  0.538182  0.595077  0.437571  0.023520  0.772187  0.862554
# 8  0.444974  0.700771  0.413958  0.097996  0.355228  0.656919
# 9  0.555009  0.263138  0.906283  0.121386  0.624336  0.859904

下面是一个超级简单的方法示例。如果您要从excel复制标题，请使用.split（'\t'）

df = df['FILE_NAME DISPLAY_PATH SHAREPOINT_PATH RETAILER LAST_UPDATE'.split()]

我很喜欢Shoresh的回答：当你不知道位置时，使用集合功能来删除列，但这不符合我的目的，因为我需要保持原始的列顺序（具有任意的列标签）。

不过，我通过使用boltons包中的IndexedSet实现了这一点。

我还需要重新添加多个列标签，因此对于更一般的情况，我使用了以下代码：

from boltons.setutils import IndexedSet
cols = list(IndexedSet(df.columns.tolist()) - set(['mean', 'std']))
cols[0:0] =['mean', 'std']
df = df[cols]

希望这对搜索此线程以寻求通用解决方案的任何人都有用。

我认为这个函数更简单。您只需在开始或结束处或同时指定列的子集：

def reorder_df_columns(df, start=None, end=None):
    """
        This function reorder columns of a DataFrame.
        It takes columns given in the list `start` and move them to the left.
        Its also takes columns in `end` and move them to the right.
    """
    if start is None:
        start = []
    if end is None:
        end = []
    assert isinstance(start, list) and isinstance(end, list)
    cols = list(df.columns)
    for c in start:
        if c not in cols:
            start.remove(c)
    for c in end:
        if c not in cols or c in start:
            end.remove(c)
    for c in start + end:
        cols.remove(c)
    cols = start + cols + end
    return df[cols]

您可以使用可用于两个轴的重新索引：

df
#           0         1         2         3         4      mean
# 0  0.943825  0.202490  0.071908  0.452985  0.678397  0.469921
# 1  0.745569  0.103029  0.268984  0.663710  0.037813  0.363821
# 2  0.693016  0.621525  0.031589  0.956703  0.118434  0.484254
# 3  0.284922  0.527293  0.791596  0.243768  0.629102  0.495336
# 4  0.354870  0.113014  0.326395  0.656415  0.172445  0.324628
# 5  0.815584  0.532382  0.195437  0.829670  0.019001  0.478415
# 6  0.944587  0.068690  0.811771  0.006846  0.698785  0.506136
# 7  0.595077  0.437571  0.023520  0.772187  0.862554  0.538182
# 8  0.700771  0.413958  0.097996  0.355228  0.656919  0.444974
# 9  0.263138  0.906283  0.121386  0.624336  0.859904  0.555009

df.reindex(['mean', *range(5)], axis=1)

#        mean         0         1         2         3         4
# 0  0.469921  0.943825  0.202490  0.071908  0.452985  0.678397
# 1  0.363821  0.745569  0.103029  0.268984  0.663710  0.037813
# 2  0.484254  0.693016  0.621525  0.031589  0.956703  0.118434
# 3  0.495336  0.284922  0.527293  0.791596  0.243768  0.629102
# 4  0.324628  0.354870  0.113014  0.326395  0.656415  0.172445
# 5  0.478415  0.815584  0.532382  0.195437  0.829670  0.019001
# 6  0.506136  0.944587  0.068690  0.811771  0.006846  0.698785
# 7  0.538182  0.595077  0.437571  0.023520  0.772187  0.862554
# 8  0.444974  0.700771  0.413958  0.097996  0.355228  0.656919
# 9  0.555009  0.263138  0.906283  0.121386  0.624336  0.859904

这里有一个函数可以对任意数量的列执行此操作。

def mean_first(df):
    ncols = df.shape[1]        # Get the number of columns
    index = list(range(ncols)) # Create an index to reorder the columns
    index.insert(0,ncols)      # This puts the last column at the front
    return(df.assign(mean=df.mean(1)).iloc[:,index]) # new df with last column (mean) first