使用正则表达式验证器:

<asp:TextBox ID="TextBoxNum" runat="server"></asp:TextBox><br />
<asp:RegularExpressionValidator ID="RegularExpressionValidator1"
                        ControlToValidate="TextBoxNum" runat="server"
                        ErrorMessage="Only numbers allowed"
                        ValidationExpression="\d+">
</asp:RegularExpressionValidator>

在我们的网页与文本框的定义，我们可以添加一个onkeypress事件只接受数字。它不会显示任何消息，但它将防止您输入错误。它为我工作，用户不能输入任何除了数字。

<asp:TextBox runat="server" ID="txtFrom"
     onkeypress="if(isNaN(String.fromCharCode(event.keyCode))) return false;">

我一直致力于一个组件的集合来完成WinForms中缺失的东西，这里是:高级表单

特别地，这是一个正则文本框类

/// <summary>Represents a Windows text box control that only allows input that matches a regular expression.</summary>
public class RegexTextBox : TextBox
{
    [NonSerialized]
    string lastText;

    /// <summary>A regular expression governing the input allowed in this text field.</summary>
    [Browsable(false), EditorBrowsable(EditorBrowsableState.Never)]
    [DesignerSerializationVisibility(DesignerSerializationVisibility.Hidden)]
    public virtual Regex Regex { get; set; }

    /// <summary>A regular expression governing the input allowed in this text field.</summary>
    [DefaultValue(null)]
    [Category("Behavior")]
    [Description("Sets the regular expression governing the input allowed for this control.")]
    public virtual string RegexString {
        get {
            return Regex == null ? string.Empty : Regex.ToString();
        }
        set {
            if (string.IsNullOrEmpty(value))
                Regex = null;
            else
                Regex = new Regex(value);
        }
    }

    protected override void OnTextChanged(EventArgs e) {
        if (Regex != null && !Regex.IsMatch(Text)) {
            int pos = SelectionStart - Text.Length + (lastText ?? string.Empty).Length;
            Text = lastText;
            SelectionStart = Math.Max(0, pos);
        }

        lastText = Text;

        base.OnTextChanged(e);
    }
}

简单地添加像myNumbericTextBox这样的东西。RegexString = "^(\\d+|)$";应该足够了。

这个功能包括复制粘贴，拖放，按下键，防止溢出，非常简单

public partial class IntegerBox : TextBox 
{
    public IntegerBox()
    {
        InitializeComponent();
        this.Text = 0.ToString();
    }

    protected override void OnPaint(PaintEventArgs pe)
    {
        base.OnPaint(pe);
    }

    private String originalValue = 0.ToString();

    private void Integerbox_KeyPress(object sender, KeyPressEventArgs e)
    {
        originalValue = this.Text;
    }

    private void Integerbox_TextChanged(object sender, EventArgs e)
    {
        try
        {
            if(String.IsNullOrWhiteSpace(this.Text))
            {
                this.Text = 0.ToString();
            }
            this.Text = Convert.ToInt64(this.Text.Trim()).ToString();
        }
        catch (System.OverflowException)
        {
            MessageBox.Show("Value entered is to large max value: " + Int64.MaxValue.ToString(), "Error", MessageBoxButtons.OK, MessageBoxIcon.Error);
            this.Text = originalValue;
        }
        catch (System.FormatException)
        {                
            this.Text = originalValue;
        }
        catch (System.Exception ex)
        {
            this.Text = originalValue;
            MessageBox.Show(ex.Message, "Error", MessageBoxButtons.OK , MessageBoxIcon.Error);
        }
    }       
}

WPF的工作解决方案&一个简单的TextChangedEventArgs。

private void TextBox_TextChanged(object sender, TextChangedEventArgs e)
{
    var TextBox = (sender as TextBox);

    // if not a numeric value, remove news characters
    if (Regex.IsMatch(TextBox.Text, "[^0-9]"))
    {
        foreach (TextChange Change in e.Changes)
        {
            TextBox.Text = TextBox.Text.Remove(Change.Offset, Change.AddedLength);

            TextBox.CaretIndex = Change.Offset;
        }
    }
}

这是用.NET 5/Core来实现的一种很好很短的方法

private void textBox1_KeyDown(object sender, KeyEventArgs e) {
  if (e.KeyData != Keys.Back)
    e.SuppressKeyPress = !int.TryParse(Convert.ToString((char) e.KeyData), out int _);
}

编辑:增加了退格键的支持