您可以在感兴趣的文件区域上通过互操作调用LockFile。这将不会抛出异常，如果它成功，你将对文件的那一部分(由你的进程持有)拥有一个锁，这个锁将一直持有，直到你调用UnlockFile或你的进程死亡。

不使用互操作，你可以使用。net FileStream类方法Lock和Unlock:

文件流。锁 http://msdn.microsoft.com/en-us/library/system.io.filestream.lock.aspx

文件流。解锁 http://msdn.microsoft.com/en-us/library/system.io.filestream.unlock.aspx

不，不幸的是，如果你仔细想想，这些信息无论如何都是毫无价值的，因为文件可能在下一秒就被锁定(阅读:短时间跨度)。

为什么您特别需要知道文件是否被锁定?知道了这一点，我们可能会以其他方式给你一些好的建议。

如果你的代码是这样的:

if not locked then
    open and update file

然后，在这两行之间，另一个进程可以很容易地锁定文件，给您带来您一开始试图避免的相同问题:异常。

当我遇到类似的问题时，我完成了以下代码:

public class FileManager
{
    private string _fileName;

    private int _numberOfTries;

    private int _timeIntervalBetweenTries;

    private FileStream GetStream(FileAccess fileAccess)
    {
        var tries = 0;
        while (true)
        {
            try
            {
                return File.Open(_fileName, FileMode.Open, fileAccess, Fileshare.None); 
            }
            catch (IOException e)
            {
                if (!IsFileLocked(e))
                    throw;
                if (++tries > _numberOfTries)
                    throw new MyCustomException("The file is locked too long: " + e.Message, e);
                Thread.Sleep(_timeIntervalBetweenTries);
            }
        }
    }

    private static bool IsFileLocked(IOException exception)
    {
        int errorCode = Marshal.GetHRForException(exception) & ((1 << 16) - 1);
        return errorCode == 32 || errorCode == 33;
    }

    // other code

}

DixonD出色答案的一个变体(如上)。

public static bool TryOpen(string path,
                           FileMode fileMode,
                           FileAccess fileAccess,
                           FileShare fileShare,
                           TimeSpan timeout,
                           out Stream stream)
{
    var endTime = DateTime.Now + timeout;

    while (DateTime.Now < endTime)
    {
        if (TryOpen(path, fileMode, fileAccess, fileShare, out stream))
            return true;
    }

    stream = null;
    return false;
}

public static bool TryOpen(string path,
                           FileMode fileMode,
                           FileAccess fileAccess,
                           FileShare fileShare,
                           out Stream stream)
{
    try
    {
        stream = File.Open(path, fileMode, fileAccess, fileShare);
        return true;
    }
    catch (IOException e)
    {
        if (!FileIsLocked(e))
            throw;

        stream = null;
        return false;
    }
}

private const uint HRFileLocked = 0x80070020;
private const uint HRPortionOfFileLocked = 0x80070021;

private static bool FileIsLocked(IOException ioException)
{
    var errorCode = (uint)Marshal.GetHRForException(ioException);
    return errorCode == HRFileLocked || errorCode == HRPortionOfFileLocked;
}

用法:

private void Sample(string filePath)
{
    Stream stream = null;

    try
    {
        var timeOut = TimeSpan.FromSeconds(1);

        if (!TryOpen(filePath,
                     FileMode.Open,
                     FileAccess.ReadWrite,
                     FileShare.ReadWrite,
                     timeOut,
                     out stream))
            return;

        // Use stream...
    }
    finally
    {
        if (stream != null)
            stream.Close();
    }
}

我最后做的是:

internal void LoadExternalData() {
    FileStream file;

    if (TryOpenRead("filepath/filename", 5, out file)) {
        using (file)
        using (StreamReader reader = new StreamReader(file)) {
         // do something 
        }
    }
}


internal bool TryOpenRead(string path, int timeout, out FileStream file) {
    bool isLocked = true;
    bool condition = true;

    do {
        try {
            file = File.OpenRead(path);
            return true;
        }
        catch (IOException e) {
            var errorCode = Marshal.GetHRForException(e) & ((1 << 16) - 1);
            isLocked = errorCode == 32 || errorCode == 33;
            condition = (isLocked && timeout > 0);

            if (condition) {
                // we only wait if the file is locked. If the exception is of any other type, there's no point on keep trying. just return false and null;
                timeout--;
                new System.Threading.ManualResetEvent(false).WaitOne(1000);
            }
        }
    }
    while (condition);

    file = null;
    return false;
}