下面是Nux给出的答案的一个变体，对我有用：

def WriteDirectoryToZipFile( zipHandle, srcPath, zipLocalPath = "", zipOperation = zipfile.ZIP_DEFLATED ):
    basePath = os.path.split( srcPath )[ 0 ]
    for root, dirs, files in os.walk( srcPath ):
        p = os.path.join( zipLocalPath, root [ ( len( basePath ) + 1 ) : ] )
        # add dir
        zipHandle.write( root, p, zipOperation )
        # add files
        for f in files:
            filePath = os.path.join( root, f )
            fileInZipPath = os.path.join( p, f )
            zipHandle.write( filePath, fileInZipPath, zipOperation )

试试下面的一个。它对我有用。

import zipfile, os
zipf = "compress.zip"  
def main():
    directory = r"Filepath"
    toZip(directory)
def toZip(directory):
    zippedHelp = zipfile.ZipFile(zipf, "w", compression=zipfile.ZIP_DEFLATED )

    list = os.listdir(directory)
    for file_list in list:
        file_name = os.path.join(directory,file_list)

        if os.path.isfile(file_name):
            print file_name
            zippedHelp.write(file_name)
        else:
            addFolderToZip(zippedHelp,file_list,directory)
            print "---------------Directory Found-----------------------"
    zippedHelp.close()

def addFolderToZip(zippedHelp,folder,directory):
    path=os.path.join(directory,folder)
    print path
    file_list=os.listdir(path)
    for file_name in file_list:
        file_path=os.path.join(path,file_name)
        if os.path.isfile(file_path):
            zippedHelp.write(file_path)
        elif os.path.isdir(file_name):
            print "------------------sub directory found--------------------"
            addFolderToZip(zippedHelp,file_name,path)


if __name__=="__main__":
    main()

# import required python modules
# You have to install zipfile package using pip install

import os,zipfile

# Change the directory where you want your new zip file to be

os.chdir('Type your destination')

# Create a new zipfile ( I called it myfile )

zf = zipfile.ZipFile('myfile.zip','w')

# os.walk gives a directory tree. Access the files using a for loop

for dirnames,folders,files in os.walk('Type your directory'):
    zf.write('Type your Directory')
    for file in files:
        zf.write(os.path.join('Type your directory',file))

使用python3.9、pathlib&zipfile模块，您可以从系统中的任何位置创建zip文件。

def zip_dir(dir: Union[Path, str], filename: Union[Path, str]):
    """Zip the provided directory without navigating to that directory using `pathlib` module"""

    # Convert to Path object
    dir = Path(dir)

    with zipfile.ZipFile(filename, "w", zipfile.ZIP_DEFLATED) as zip_file:
        for entry in dir.rglob("*"):
            zip_file.write(entry, entry.relative_to(dir))

它整洁、打字，代码更少。

此函数将递归地压缩目录树，压缩文件，并在存档中记录正确的相对文件名。存档条目与zip-r output.zip source_dir生成的条目相同。

import os
import zipfile
def make_zipfile(output_filename, source_dir):
    relroot = os.path.abspath(os.path.join(source_dir, os.pardir))
    with zipfile.ZipFile(output_filename, "w", zipfile.ZIP_DEFLATED) as zip:
        for root, dirs, files in os.walk(source_dir):
            # add directory (needed for empty dirs)
            zip.write(root, os.path.relpath(root, relroot))
            for file in files:
                filename = os.path.join(root, file)
                if os.path.isfile(filename): # regular files only
                    arcname = os.path.join(os.path.relpath(root, relroot), file)
                    zip.write(filename, arcname)

您可能想看看zipfile模块；文档位于http://docs.python.org/library/zipfile.html.

您可能还需要os.walk（）来索引目录结构。