# FIRST METHOD
# Storing all punctuations in a variable    
punctuation='!?,.:;"\')(_-'
newstring ='' # Creating empty string
word = raw_input("Enter string: ")
for i in word:
     if(i not in punctuation):
                  newstring += i
print ("The string without punctuation is", newstring)

# SECOND METHOD
word = raw_input("Enter string: ")
punctuation = '!?,.:;"\')(_-'
newstring = word.translate(None, punctuation)
print ("The string without punctuation is",newstring)


# Output for both methods
Enter string: hello! welcome -to_python(programming.language)??,
The string without punctuation is: hello welcome topythonprogramminglanguage

import re
s = "string. With. Punctuation?" # Sample string 
out = re.sub(r'[^a-zA-Z0-9\s]', '', s)

字符串标点符号仅为ASCII！一种更正确（但也慢得多）的方法是使用unicodedata模块：

# -*- coding: utf-8 -*-
from unicodedata import category
s = u'String — with -  «punctation »...'
s = ''.join(ch for ch in s if category(ch)[0] != 'P')
print 'stripped', s

您还可以概括和剥离其他类型的字符：

''.join(ch for ch in s if category(ch)[0] not in 'SP')

它还将删除~*+§$等字符，这些字符可能是“标点符号”，也可能不是“标点符号。

>>> s = "string. With. Punctuation?"
>>> s = re.sub(r'[^\w\s]','',s)
>>> re.split(r'\s*', s)


['string', 'With', 'Punctuation']

我喜欢使用这样的函数：

def scrub(abc):
    while abc[-1] is in list(string.punctuation):
        abc=abc[:-1]
    while abc[0] is in list(string.punctuation):
        abc=abc[1:]
    return abc

您也可以这样做：

import string
' '.join(word.strip(string.punctuation) for word in 'text'.split())