# FIRST METHOD
# Storing all punctuations in a variable    
punctuation='!?,.:;"\')(_-'
newstring ='' # Creating empty string
word = raw_input("Enter string: ")
for i in word:
     if(i not in punctuation):
                  newstring += i
print ("The string without punctuation is", newstring)

# SECOND METHOD
word = raw_input("Enter string: ")
punctuation = '!?,.:;"\')(_-'
newstring = word.translate(None, punctuation)
print ("The string without punctuation is",newstring)


# Output for both methods
Enter string: hello! welcome -to_python(programming.language)??,
The string without punctuation is: hello welcome topythonprogramminglanguage

不一定更简单，但如果你更熟悉re家族的话，就另辟蹊径。

import re, string
s = "string. With. Punctuation?" # Sample string 
out = re.sub('[%s]' % re.escape(string.punctuation), '', s)

这里有一个使用RegEx的简单方法

import re

punct = re.compile(r'(\w+)')

sentence = 'This ! is : a # sample $ sentence.' # Text with punctuation
tokenized = [m.group() for m in punct.finditer(sentence)]
sentence = ' '.join(tokenized)
print(sentence) 
'This is a sample sentence'

我还没有看到这个答案。只需使用正则表达式；它删除了除单词字符（\w）和数字字符（\d）之外的所有字符，后跟一个空白字符（\s）：

import re
s = "string. With. Punctuation?" # Sample string 
out = re.sub(ur'[^\w\d\s]+', '', s)

为什么你们都不用这个？

 ''.join(filter(str.isalnum, s)) 

太慢了？

这是我写的一个函数。它不是很有效，但很简单，您可以添加或删除任何您想要的标点符号：

def stripPunc(wordList):
    """Strips punctuation from list of words"""
    puncList = [".",";",":","!","?","/","\\",",","#","@","$","&",")","(","\""]
    for punc in puncList:
        for word in wordList:
            wordList=[word.replace(punc,'') for word in wordList]
    return wordList