var compare = array1.length > array2.length ? array1 : array2;
var compareWith = array1.length > array2.length ? array2 : array1;
var uniqueValues = compareWith.filter(function(value){
                    if(compare.indexOf(vakye) == -1)
                       return true;
                   });

这将检查数组中哪个更大，然后进行比较。

这个问题很老了，但仍然是javascript数组减法的热门问题，所以我想添加我正在使用的解决方案。适用于以下情况:

var a1 = [1,2,2,3]
var a2 = [1,2]
//result = [2,3]

下面的方法将产生预期的结果:

function arrayDifference(minuend, subtrahend) {
  for (var i = 0; i < minuend.length; i++) {
    var j = subtrahend.indexOf(minuend[i])
    if (j != -1) {
      minuend.splice(i, 1);
      subtrahend.splice(j, 1);
    }
  }
  return minuend;
}

需要注意的是，该函数不包括减数中没有被减数的值:

var a1 = [1,2,3]
var a2 = [2,3,4]
//result = [1]

贡献一个jQuery解决方案，我目前正在使用:

if (!Array.prototype.diff) {
    Array.prototype.diff = function (a) {
        return $.grep(this, function (i) { return $.inArray(i, a) === -1; });
    }; 
}

**这将根据'type'参数为任意2个数组返回一个唯一值数组，或一个重复值数组，或一个非重复值数组(difference)。**

let json1 = ['one', 'two']
let json2 = ['one', 'two', 'three', 'four']

function uniq_n_shit (arr1, arr2, type) {

  let concat = arr1.concat(arr2)
  let set = [...new Set(concat)]

  if (!type || type === 'uniq' || type === 'unique') {

    return set

  } else if (type === 'duplicate') {

    concat = arr1.concat(arr2)
    return concat.filter(function (obj, index, self) {
      return index !== self.indexOf(obj)
    })

  } else if (type === 'not_duplicate') {

    let duplicates = concat.filter(function (obj, index, self) {
      return index !== self.indexOf(obj)
    })

    for (let r = 0; r < duplicates.length; r++) {
      let i = set.indexOf(duplicates[r]);
      if(i !== -1) {
        set.splice(i, 1);
      }
    }

    return set

  }
}

console.log(uniq_n_shit(json1, json2, null)) // => [ 'one', 'two', 'three', 'four' ]
console.log(uniq_n_shit(json1, json2, 'uniq')) // => [ 'one', 'two', 'three', 'four' ]
console.log(uniq_n_shit(json1, json2, 'duplicate')) // => [ 'one', 'two' ]
console.log(uniq_n_shit(json1, json2, 'not_duplicate')) // => [ 'three', 'four' ]

var arrayDifference = function(arr1, arr2){
  if(arr1 && arr1.length){
    if(arr2 && arr2.length > 0){
      for (var i=0, itemIndex; i<arr2.length; i++){
        itemIndex = arr1.indexOf(arr2[i]);
        if(itemIndex !== -1){
          arr1.splice(itemIndex, 1);
        }
      }
    }
    return arr1;
  }
  return [];
};

arrayDifference([1,2,3,4,5], [1,5,6]);

var result = [];
var arr1 = [1,2,3,4];
var arr2 = [2,3];
arr1.forEach(function(el, idx) {
    function unEqual(element, index, array) {
        var a = el;
        return (element!=a);
    }
    if (arr2.every(unEqual)) {
        result.push(el);
    };
});
alert(result);