下面是@arkolec的回答，下面是一个用于比较列表、元组和集的实用程序类:

from difflib import SequenceMatcher

class ListDiffer:

    def __init__(self, left, right, strict:bool=False):
        assert isinstance(left, (list, tuple, set)), "left must be list, tuple or set"
        assert isinstance(right, (list, tuple, set)), "right must be list, tuple or set"
        self.l = list(left) if isinstance(left, (tuple, set)) else left
        self.r = list(right) if isinstance(left, (tuple, set)) else right

        if strict:
            assert isinstance(left, right.__class__), \
                f'left type ({left.__class__.__name__}) must equal right type ({right.__class__.__name__})'

        self.diffs = []
        self.equal = []

        for tag, i, j, k, l in SequenceMatcher(None, self.l, self.r).get_opcodes():
            if tag in ['delete', 'replace', 'insert']:
                self.diffs.append((tag, i, j, k, l))
            elif tag == 'equal':
                [self.equal.append(v) for v in left[i:j]]
                


    def has_diffs(self):
        return len(self.diffs) > 0


    def only_left(self):
        a = self.l[:]
        [a.remove(v) for v in self.equal]
        return a

    def only_right(self):
        a = self.r[:]
        [a.remove(v) for v in self.equal]
        return a


    def __str__(self, verbose:bool=False):
        iD = 0
        sb = []
        if verbose:
            sb.append(f"left: {self.l}\n")
            sb.append(f"right: {self.r}\n")
            sb.append(f"diffs: ")
        for tag, i, j, k, l in self.diffs:
            s = f"({iD})"
            if iD > 0: sb.append(' | ')
            if tag in ('delete', 'replace'): s = f'{s} l:{self.l[i:j]}'
            if tag in ('insert', 'replace'): s = f'{s} r:{self.r[k:l]}'
            sb.append(s)
            iD = iD + 1

        if verbose:
            sb.append(f"\nequal: {self.equal}")
        return ''.join(sb)

    def __repr__(self) -> str:
        return "<ListDiffer> {}".format(self.__str__())

用法:

left = ['a','b','c']
right = ['aa','b','c','d']
# right = ('aa','b','c','d')
ld = ListDiffer(left, right, strict=True)
print(f'ld.has_diffs(): {ld.has_diffs()}')
print(f'ld: {ld}')
print(f'ld.only_left(): {ld.only_left()}')
print(f'ld.only_right(): {ld.only_right()}')

输出:

ld.has_diffs(): True
ld: (0) l:['a'] r:['aa'] | (1) r:['d']
ld.only_left(): ['a']
ld.only_right(): ['aa', 'd']

我不能说性能，但你可以使用ld.only_left()来获得你正在寻找的结果。

由于目前的解决方案都不产生一个元组，我将抛出:

temp3 = tuple(set(temp1) - set(temp2))

另外:

#edited using @Mark Byers idea. If you accept this one as answer, just accept his instead.
temp3 = tuple(x for x in temp1 if x not in set(temp2))

像其他在这个方向上得到答案的非元组一样，它保持了顺序

试试这个:

temp3 = set(temp1) - set(temp2)

以下是@SuperNova的回答的修改版本

def get_diff(a: list, b: list) -> list:
    return list(set(a) ^ set(b))

这是另一个解决方案:

def diff(a, b):
    xa = [i for i in set(a) if i not in b]
    xb = [i for i in set(b) if i not in a]
    return xa + xb

获取在temp1中而不在temp2中的元素 (假设每个列表中的元素是唯一的):

In [5]: list(set(temp1) - set(temp2))
Out[5]: ['Four', 'Three']

注意它是不对称的 :

In [5]: set([1, 2]) - set([2, 3])
Out[5]: set([1]) 

这里您可能期望/希望它等于set([1,3])。如果你想要set([1,3])作为你的答案，你可以使用set([1,2])。symmetric_difference(设置([2、3]))。