我更喜欢这种方法，因为它更通用，即你可以在文件上使用它，在f.r edlines()的结果上，在StringIO对象上，无论什么:

def read_specific_lines(file, lines_to_read):
   """file is any iterable; lines_to_read is an iterable containing int values"""
   lines = set(lines_to_read)
   last = max(lines)
   for n, line in enumerate(file):
      if n + 1 in lines:
          yield line
      if n + 1 > last:
          return

>>> with open(r'c:\temp\words.txt') as f:
        [s for s in read_specific_lines(f, [1, 2, 3, 1000])]
['A\n', 'a\n', 'aa\n', 'accordant\n']

如果要读取的文件很大，并且你不想一次在内存中读取整个文件:

fp = open("file")
for i, line in enumerate(fp):
    if i == 25:
        # 26th line
    elif i == 29:
        # 30th line
    elif i > 29:
        break
fp.close()

注意第n行i == n-1。

在Python 2.6或更高版本中:

with open("file") as fp:
    for i, line in enumerate(fp):
        if i == 25:
            # 26th line
        elif i == 29:
            # 30th line
        elif i > 29:
            break

为了完整起见，这里还有一个选项。

让我们从python文档中的定义开始:

通常包含序列的一部分的对象。slice使用下标符号[]创建，当给出几个数字时，数字之间使用冒号，例如variable_name[1:3:5]。括号(下标)表示法在内部使用切片对象(或在旧版本中使用__getslice__()和__setslice__())。

虽然slice表示法一般不直接适用于迭代器，但itertools包包含一个替换函数:

from itertools import islice

# print the 100th line
with open('the_file') as lines:
    for line in islice(lines, 99, 100):
        print line

# print each third line until 100
with open('the_file') as lines:
    for line in islice(lines, 0, 100, 3):
        print line

该函数的另一个优点是，它直到结束才读取迭代器。所以你可以做更复杂的事情:

with open('the_file') as lines:
    # print the first 100 lines
    for line in islice(lines, 100):
        print line

    # then skip the next 5
    for line in islice(lines, 5):
        pass

    # print the rest
    for line in lines:
        print line

为了回答最初的问题:

# how to read lines #26 and #30
In [365]: list(islice(xrange(1,100), 25, 30, 4))
Out[365]: [26, 30]

不要使用阅读线!

我的解决方案是:

with open(filename) as f:
    specify = [26, 30]
    results = list(
        map(lambda line: line[1],
            filter(lambda line: line[0] in specify,
                   enumerate(f))
            )
    )

对6.5G文件进行如下测试:

import time

filename = 'a.txt'
start = time.time()
with open(filename, 'w') as f:
    for i in range(10_000_000):
        f.write(f'{str(i)*100}\n')       
end1 = time.time()

with open(filename) as f:
    specify = [26, 30]
    results = list(
        map(lambda line: line[1],
            filter(lambda line: line[0] in specify,
                   enumerate(f))
            )
    )
end2 = time.time()
print(f'write time: {end1-start}')
print(f'read time: {end2-end1}')
# write time: 14.38945460319519
# read time: 8.380386352539062

这是我的2美分，不管它是否值得;)

def indexLines(filename, lines=[2,4,6,8,10,12,3,5,7,1]):
    fp   = open(filename, "r")
    src  = fp.readlines()
    data = [(index, line) for index, line in enumerate(src) if index in lines]
    fp.close()
    return data


# Usage below
filename = "C:\\Your\\Path\\And\\Filename.txt"
for line in indexLines(filename): # using default list, specify your own list of lines otherwise
    print "Line: %s\nData: %s\n" % (line[0], line[1])

def getitems(iterable, items):
  items = list(items) # get a list from any iterable and make our own copy
                      # since we modify it
  if items:
    items.sort()
    for n, v in enumerate(iterable):
      if n == items[0]:
        yield v
        items.pop(0)
        if not items:
          break

print list(getitems(open("/usr/share/dict/words"), [25, 29]))
# ['Abelson\n', 'Abernathy\n']
# note that index 25 is the 26th item