XmlSerializer函数。FromTypes不会抛出异常，但它会泄漏内存。这就是为什么你需要为每个类型缓存这样的序列化器，以避免内存泄漏为每个创建的实例。

创建自己的XmlSerializer工厂并简单地使用它:

XmlSerializer serializer = XmlSerializerFactoryNoThrow.Create(typeof(MyType));

工厂是这样的:

public static class XmlSerializerFactoryNoThrow
{
    public static Dictionary<Type, XmlSerializer> _cache = new Dictionary<Type, XmlSerializer>();

    private static object SyncRootCache = new object();        

    /// <summary>
    /// //the constructor XmlSerializer.FromTypes does not throw exception, but it is said that it causes memory leaks
    /// http://stackoverflow.com/questions/1127431/xmlserializer-giving-filenotfoundexception-at-constructor
    /// That is why I use dictionary to cache the serializers my self.
    /// </summary>
    public static XmlSerializer Create(Type type)
    {
        XmlSerializer serializer;

        lock (SyncRootCache)
        {
            if (_cache.TryGetValue(type, out serializer))
                return serializer;
        }

        lock (type) //multiple variable of type of one type is same instance
        {
            //constructor XmlSerializer.FromTypes does not throw the first chance exception           
            serializer = XmlSerializer.FromTypes(new[] { type })[0];
            //serializer = XmlSerializerFactoryNoThrow.Create(type);
        }

        lock (SyncRootCache)
        {
            _cache[type] = serializer;
        }
        return serializer;
    }       
}

更复杂的版本，没有内存泄漏的可能性(请有人检查代码):

    public static XmlSerializer Create(Type type)
    {
        XmlSerializer serializer;

        lock (SyncRootCache)
        {
            if (_cache.TryGetValue(type, out serializer))
                return serializer;
        }

        lock (type) //multiple variable of type of one type is same instance
        {
            lock (SyncRootCache)
            {
                if (_cache.TryGetValue(type, out serializer))
                    return serializer;
            }
            serializer = XmlSerializer.FromTypes(new[] { type })[0];
            lock (SyncRootCache)
            {
                _cache[type] = serializer;
            }
        }          
        return serializer;
    }       
}

另一方面，对编译错误进行故障排除是非常复杂的。这些问题在FileNotFoundException异常中显示，并显示如下信息:

File or assembly name abcdef.dll, or one of its dependencies, was not found. File name: "abcdef.dll"
   at System.Reflection.Assembly.nLoad( ... )
   at System.Reflection.Assembly.InternalLoad( ... )
   at System.Reflection.Assembly.Load(...)
   at System.CodeDom.Compiler.CompilerResults.get_CompiledAssembly() 

You may wonder what a file not found exception has to do with instantiating a serializer object, but remember: the constructor writes C# files and tries to compile them. The call stack of this exception provides some good information to support that suspicion. The exception occurred while the XmlSerializer attempted to load an assembly generated by CodeDOM calling the System.Reflection.Assembly.Load method. The exception does not provide an explanation as to why the assembly that the XmlSerializer was supposed to create was not present. In general, the assembly is not present because the compilation failed, which may happen because, under rare circumstances, the serialization attributes produce code that the C# compiler fails to compile.

请注意 当XmlSerializer在不能访问临时目录的帐户或安全环境下运行时，也会发生此错误。

来源: http://msdn.microsoft.com/en-us/library/aa302290.aspx

我也有同样的问题，直到我使用第三方工具从XSD生成类，它工作了!我发现这个工具在类的顶部添加了一些额外的代码。当我把同样的代码添加到我原来的类的顶部时，它起作用了。以下是我添加的内容……

#pragma warning disable
namespace MyNamespace
{
  using System;
  using System.Diagnostics;
  using System.Xml.Serialization;
  using System.Collections;
  using System.Xml.Schema;
  using System.ComponentModel;
  using System.Xml;
  using System.Collections.Generic;

  [System.CodeDom.Compiler.GeneratedCodeAttribute("System.Xml", "4.6.1064.2")]
  [System.SerializableAttribute()]
  [System.Diagnostics.DebuggerStepThroughAttribute()]
  [System.ComponentModel.DesignerCategoryAttribute("code")]
  [System.Xml.Serialization.XmlTypeAttribute(AnonymousType = true)]
  [System.Xml.Serialization.XmlRootAttribute(Namespace = "", IsNullable = false)]
  public partial class MyClassName
  {
  ...

在Visual Studio项目属性(“Build”页面，如果我没记错的话)中有一个选项显示“生成序列化程序集”。尝试为生成[包含MyType的程序集]的项目打开该选项。

此异常也可以由名为BindingFailure的托管调试助手(MDA)捕获。

如果您的应用程序被设计为附带预构建序列化程序集，则此MDA非常有用。这样做是为了提高应用程序的性能。它允许我们确保预先构建的序列化程序集由构建过程正确构建，并由应用程序加载，而无需动态重新构建。

除了在这种情况下，它实际上没什么用，因为正如其他帖子所说，当绑定错误被Serializer构造函数捕获时，序列化程序集将在运行时重新构建。所以你可以把它关掉。

您的类型可能会引用在GAC和本地bin文件夹中都找不到的其他程序集==>…

或其依赖项之一。该系统 无法找到指定的文件"

您能举例说明要序列化的类型吗?

注意:确保你的类型实现Serializable。