我也有同样的问题，直到我使用第三方工具从XSD生成类，它工作了!我发现这个工具在类的顶部添加了一些额外的代码。当我把同样的代码添加到我原来的类的顶部时，它起作用了。以下是我添加的内容……

#pragma warning disable
namespace MyNamespace
{
  using System;
  using System.Diagnostics;
  using System.Xml.Serialization;
  using System.Collections;
  using System.Xml.Schema;
  using System.ComponentModel;
  using System.Xml;
  using System.Collections.Generic;

  [System.CodeDom.Compiler.GeneratedCodeAttribute("System.Xml", "4.6.1064.2")]
  [System.SerializableAttribute()]
  [System.Diagnostics.DebuggerStepThroughAttribute()]
  [System.ComponentModel.DesignerCategoryAttribute("code")]
  [System.Xml.Serialization.XmlTypeAttribute(AnonymousType = true)]
  [System.Xml.Serialization.XmlRootAttribute(Namespace = "", IsNullable = false)]
  public partial class MyClassName
  {
  ...

要序列化的自定义类:

[Serializable]
public class TestClass
{
    int x = 2;
    int y = 4;
    public TestClass(){}
    public TestClass(int x, int y)
    {
        this.x = x;
        this.y = y;
    }

    public int TestFunction()
    {
        return x + y;
    }
}

我已经附上了代码片段。也许这个能帮到你。

static void Main(string[] args)
{
    XmlSerializer xmlSerializer = new XmlSerializer(typeof(TestClass));

    MemoryStream memoryStream = new MemoryStream();
    XmlTextWriter xmlWriter = new XmlTextWriter(memoryStream, Encoding.UTF8);

    TestClass domain = new TestClass(10, 3);
    xmlSerializer.Serialize(xmlWriter, domain);
    memoryStream = (MemoryStream)xmlWriter.BaseStream;
    string xmlSerializedString = ConvertByteArray2Str(memoryStream.ToArray());

    TestClass xmlDomain = (TestClass)DeserializeObject(xmlSerializedString);

    Console.WriteLine(xmlDomain.TestFunction().ToString());
    Console.ReadLine();
}

我得到了同样的错误，这是由于我试图反序列化的类型没有默认的无参数构造函数。我添加了一个构造函数，它开始工作了。

XmlSerializer函数。FromTypes不会抛出异常，但它会泄漏内存。这就是为什么你需要为每个类型缓存这样的序列化器，以避免内存泄漏为每个创建的实例。

创建自己的XmlSerializer工厂并简单地使用它:

XmlSerializer serializer = XmlSerializerFactoryNoThrow.Create(typeof(MyType));

工厂是这样的:

public static class XmlSerializerFactoryNoThrow
{
    public static Dictionary<Type, XmlSerializer> _cache = new Dictionary<Type, XmlSerializer>();

    private static object SyncRootCache = new object();        

    /// <summary>
    /// //the constructor XmlSerializer.FromTypes does not throw exception, but it is said that it causes memory leaks
    /// http://stackoverflow.com/questions/1127431/xmlserializer-giving-filenotfoundexception-at-constructor
    /// That is why I use dictionary to cache the serializers my self.
    /// </summary>
    public static XmlSerializer Create(Type type)
    {
        XmlSerializer serializer;

        lock (SyncRootCache)
        {
            if (_cache.TryGetValue(type, out serializer))
                return serializer;
        }

        lock (type) //multiple variable of type of one type is same instance
        {
            //constructor XmlSerializer.FromTypes does not throw the first chance exception           
            serializer = XmlSerializer.FromTypes(new[] { type })[0];
            //serializer = XmlSerializerFactoryNoThrow.Create(type);
        }

        lock (SyncRootCache)
        {
            _cache[type] = serializer;
        }
        return serializer;
    }       
}

更复杂的版本，没有内存泄漏的可能性(请有人检查代码):

    public static XmlSerializer Create(Type type)
    {
        XmlSerializer serializer;

        lock (SyncRootCache)
        {
            if (_cache.TryGetValue(type, out serializer))
                return serializer;
        }

        lock (type) //multiple variable of type of one type is same instance
        {
            lock (SyncRootCache)
            {
                if (_cache.TryGetValue(type, out serializer))
                    return serializer;
            }
            serializer = XmlSerializer.FromTypes(new[] { type })[0];
            lock (SyncRootCache)
            {
                _cache[type] = serializer;
            }
        }          
        return serializer;
    }       
}

有一个变通的办法。如果你使用

XmlSerializer lizer = XmlSerializer.FromTypes(new[] { typeof(MyType) })[0];

它应该避免这种异常。这对我很管用。

警告:不要多次使用，否则会出现内存泄漏

如果多次使用此方法为同一类型创建XmlSerializer实例，将会导致内存严重泄漏!

这是因为该方法绕过了内置缓存提供的XmlSerializer(type)和XmlSerializer(type, defaultNameSpace)构造函数(所有其他构造函数也绕过缓存)。

如果使用任何方法来创建XmlSerializer，而不是通过这两个构造函数，那么必须实现自己的缓存，否则会导致内存泄漏。

Like Martin Sherburn said, this is normal behavior. The constructor of the XmlSerializer first tries to find an assembly named [YourAssembly].XmlSerializers.dll which should contain the generated class for serialization of your type. Since such a DLL has not been generated yet (they are not by default), a FileNotFoundException is thrown. When that happenes, XmlSerializer's constructor catches that exception, and the DLL is generated automatically at runtime by the XmlSerializer's constructor (this is done by generating C# source files in the %temp% directory of your computer, then compiling them using the C# compiler). Additional constructions of an XmlSerializer for the same type will just use the already generated DLL.

更新:从。net 4.5开始，XmlSerializer不再执行代码生成，也不再为了在运行时创建序列化程序集而使用c#编译器执行编译，除非通过设置配置文件设置(useLegacySerializerGeneration)显式强制执行。此更改消除了对csc.exe的依赖，并提高了启动性能。来源:. net Framework 4.5 Readme，章节1.3.8.1。

异常由XmlSerializer的构造函数处理。你不需要自己做任何事情，你可以点击“继续”(F5)继续执行你的程序，一切都会好的。如果你被异常停止程序执行并弹出异常助手所困扰，你要么关闭“只是我的代码”，要么将FileNotFoundException设置为在抛出时中断执行，而不是在“User-unhandled”时。

打开“Just My Code”，请转到“Tools >> Options >> Debugging >> General >> enable Just My Code”。要关闭FileNotFound被抛出时的执行中断，请转到调试>>异常>>找到>>输入'FileNotFoundException' >>取消System.IO.FileNotFoundException中的' thrown '复选框。