为了避免Gmail的安全问题，你应该先从Gmail的设置中生成一个应用程序密码，即使你使用两步验证，你也可以使用这个密码而不是真实密码来发送电子邮件。

编辑2022 从2022年5月30日起，谷歌将不再支持仅使用用户名和密码登录谷歌账户的第三方应用程序或设备。 但是你仍然可以通过你的gmail账户发送电子邮件。

访问https://myaccount.google.com/security，打开两步验证。如有需要，请电话确认。 点击“应用程序密码”，就在“2步验证”勾的下方。 请求邮件应用程序的新密码。

现在只需使用这个密码，而不是原来的一个为您的帐户!

public static void SendMail2Step(string SMTPServer, int SMTP_Port, string From, string Password, string To, string Subject, string Body, string[] FileNames) {            
            var smtpClient = new SmtpClient(SMTPServer, SMTP_Port) {
                DeliveryMethod = SmtpDeliveryMethod.Network,
                UseDefaultCredentials = false,
                EnableSsl = true
            };                
            smtpClient.Credentials = new NetworkCredential(From, Password); //Use the new password, generated from google!
            var message = new System.Net.Mail.MailMessage(new System.Net.Mail.MailAddress(From, "SendMail2Step"), new System.Net.Mail.MailAddress(To, To));
            smtpClient.Send(message);
    }

像这样使用:

SendMail2Step("smtp.gmail.com", 587, "youraccount@gmail.com",
          "yjkjcipfdfkytgqv",//This will be generated by google, copy it here.
          "recipient@barcodes.bg", "test message subject", "Test message body ...", null);

对于其他答案工作“从服务器”首先打开访问gmail帐户不太安全的应用程序。这将在2022年5月30日被弃用

看来最近谷歌改变了安全策略。评分最高的答案不再有效，直到您更改您的帐户设置如下所述:https://support.google.com/accounts/answer/6010255?hl=en-GB 2016年3月，谷歌再次更改设置地点!

using System;
using System.Net;
using System.Net.Mail;

namespace SendMailViaGmail
{
   class Program
   {
   static void Main(string[] args)
   {

      //Specify senders gmail address
      string SendersAddress = "Sendersaddress@gmail.com";
      //Specify The Address You want to sent Email To(can be any valid email address)
      string ReceiversAddress = "ReceiversAddress@yahoo.com";
      //Specify The password of gmial account u are using to sent mail(pw of sender@gmail.com)
      const string SendersPassword = "Password";
      //Write the subject of ur mail
      const string subject = "Testing";
      //Write the contents of your mail
      const string body = "Hi This Is my Mail From Gmail";

      try
      {
        //we will use Smtp client which allows us to send email using SMTP Protocol
        //i have specified the properties of SmtpClient smtp within{}
        //gmails smtp server name is smtp.gmail.com and port number is 587
        SmtpClient smtp = new SmtpClient
        {
           Host = "smtp.gmail.com",
           Port = 587,
           EnableSsl = true,
           DeliveryMethod = SmtpDeliveryMethod.Network,
           Credentials = new NetworkCredential(SendersAddress, SendersPassword),
           Timeout = 3000
        };

        //MailMessage represents a mail message
        //it is 4 parameters(From,TO,subject,body)

        MailMessage message = new MailMessage(SendersAddress, ReceiversAddress, subject, body);
        /*WE use smtp sever we specified above to send the message(MailMessage message)*/

        smtp.Send(message);
        Console.WriteLine("Message Sent Successfully");
        Console.ReadKey();
     }
     catch (Exception ex)
     {
        Console.WriteLine(ex.Message);
        Console.ReadKey();
     }
}
}
}

试试这个,

    private void button1_Click(object sender, EventArgs e)
    {
        try
        {
            MailMessage mail = new MailMessage();
            SmtpClient SmtpServer = new SmtpClient("smtp.gmail.com");

            mail.From = new MailAddress("your_email_address@gmail.com");
            mail.To.Add("to_address");
            mail.Subject = "Test Mail";
            mail.Body = "This is for testing SMTP mail from GMAIL";

            SmtpServer.Port = 587;
            SmtpServer.Credentials = new System.Net.NetworkCredential("username", "password");
            SmtpServer.EnableSsl = true;

            SmtpServer.Send(mail);
            MessageBox.Show("mail Send");
        }
        catch (Exception ex)
        {
            MessageBox.Show(ex.ToString());
        }
    }

从另一个答案复制，上述方法工作，但gmail总是替换“从”和“回复”电子邮件与实际发送gmail帐户。然而，显然有一种方法:

http://karmic-development.blogspot.in/2013/10/send-email-from-aspnet-using-gmail-as.html

“3。在帐户选项卡，点击链接“添加另一个电子邮件地址你自己的”，然后验证它

或者可能是这个

更新3:读者德里克·贝内特说:“解决办法是进入你的gmail设置:账户，并“默认”一个gmail账户以外的账户。这将导致gmail用默认帐户的电子邮件地址重写From字段。”

你可以试试Mailkit。它为发送邮件提供了更好、更先进的功能。这里有一个例子

    MimeMessage message = new MimeMessage();
    message.From.Add(new MailboxAddress("FromName", "YOU_FROM_ADDRESS@gmail.com"));
    message.To.Add(new MailboxAddress("ToName", "YOU_TO_ADDRESS@gmail.com"));
    message.Subject = "MyEmailSubject";

    message.Body = new TextPart("plain")
    {
        Text = @"MyEmailBodyOnlyTextPart"
    };

    using (var client = new SmtpClient())
    {
        client.Connect("SERVER", 25); // 25 is port you can change accordingly

        // Note: since we don't have an OAuth2 token, disable
        // the XOAUTH2 authentication mechanism.
        client.AuthenticationMechanisms.Remove("XOAUTH2");

        // Note: only needed if the SMTP server requires authentication
        client.Authenticate("YOUR_USER_NAME", "YOUR_PASSWORD");

        client.Send(message);
        client.Disconnect(true);
    }