此方法适用于iOS 6和7

- (float)heightForLabelSize:(CGSize)maximumLabelSize  Font:(UIFont *)font String:(NSString*)string {

if ([[[UIDevice currentDevice] systemVersion] floatValue] >= 7) {
    NSDictionary *stringAttributes = [NSDictionary dictionaryWithObject:font forKey: NSFontAttributeName];

    CGSize adjustedLabelSize = [string maximumLabelSize
                                                                  options:NSStringDrawingTruncatesLastVisibleLine|NSStringDrawingUsesLineFragmentOrigin
                                                               attributes:stringAttributes context:nil].size;
    return adjustedLabelSize.height;
}
else {
    CGSize adjustedLabelSize = [string sizeWithFont:font constrainedToSize:maximumLabelSize lineBreakMode:NSLineBreakByWordWrapping];

    return adjustedLabelSize.height;
}

}

要在Swift3中做到这一点，以下是代码:

 let labelSizeWithFixedWith = CGSize(width: 300, height: CGFloat.greatestFiniteMagnitude)
            let exactLabelsize = self.label.sizeThatFits(labelSizeWithFixedWith)
            self.label.frame = CGRect(origin: CGPoint(x: 20, y: 20), size: exactLabelsize)

当自动布局被启用时，调整大小不工作:)

谢谢大家的帮助，这是我尝试的代码，这是为我工作

   UILabel *instructions = [[UILabel alloc]initWithFrame:CGRectMake(10, 225, 300, 180)];
   NSString *text = @"First take clear picture and then try to zoom in to fit the ";
   instructions.text = text;
   instructions.textAlignment = UITextAlignmentCenter;
   instructions.lineBreakMode = NSLineBreakByWordWrapping;
   [instructions setTextColor:[UIColor grayColor]];

   CGSize expectedLabelSize = [text sizeWithFont:instructions.font 
                                constrainedToSize:instructions.frame.size
                                    lineBreakMode:UILineBreakModeWordWrap];

    CGRect newFrame = instructions.frame;
    newFrame.size.height = expectedLabelSize.height;
    instructions.frame = newFrame;
    instructions.numberOfLines = 0;
    [instructions sizeToFit];
    [self addSubview:instructions];

根据iOS7更新

// If description are available for protocol
protocolDescriptionLabel.text = [dataDictionary objectForKey:@"description"];
[protocolDescriptionLabel sizeToFit];
[protocolDescriptionLabel setLineBreakMode:NSLineBreakByWordWrapping];

CGSize expectedLabelSize = [protocolDescriptionLabel
               textRectForBounds:protocolDescriptionLabel.frame
               limitedToNumberOfLines:protocolDescriptionLabel.numberOfLines].size;
NSLog(@"expectedLabelSize %f", expectedLabelSize.height);

//adjust the label the the new height.
CGRect newFrame = protocolDescriptionLabel.frame;
newFrame.size.height = expectedLabelSize.height;
protocolDescriptionLabel.frame = newFrame;

myLabel.text = "your very long text"
myLabel.numberOfLines = 0
myLabel.lineBreakMode = NSLineBreakMode.ByWordWrapping

请在故事板中为可用性设置约束，包括左上右下