在摆弄了@journois的答案后，由于Panel的弃用，我能够使用MultiIndex而不是Panel来工作。

首先，创建一些虚拟数据:

df1 = pd.DataFrame({
    'id': ['111', '222', '333', '444', '555'],
    'let': ['a', 'b', 'c', 'd', 'e'],
    'num': ['1', '2', '3', '4', '5']
})
df2 = pd.DataFrame({
    'id': ['111', '222', '333', '444', '666'],
    'let': ['a', 'b', 'c', 'D', 'f'],
    'num': ['1', '2', 'Three', '4', '6'],
})

然后，定义你的diff函数，在这种情况下，我将使用他的答案report_diff保持不变:

def report_diff(x):
    return x[0] if x[0] == x[1] else '{} | {}'.format(*x)

然后，我将数据连接到一个MultiIndex数据框架:

df_all = pd.concat(
    [df1.set_index('id'), df2.set_index('id')], 
    axis='columns', 
    keys=['df1', 'df2'],
    join='outer'
)
df_all = df_all.swaplevel(axis='columns')[df1.columns[1:]]

最后，我将对每个列组应用report_diff:

df_final.groupby(level=0, axis=1).apply(lambda frame: frame.apply(report_diff, axis=1))

这个输出:

         let        num
111        a          1
222        b          2
333        c  3 | Three
444    d | D          4
555  e | nan    5 | nan
666  nan | f    nan | 6

这就是全部!

我遇到过这个问题，但在找到这篇文章之前找到了答案:

根据unutbu的回答，加载你的数据…

import pandas as pd
import io

texts = ['''\
id   Name   score                    isEnrolled                       Date
111  Jack                            True              2013-05-01 12:00:00
112  Nick   1.11                     False             2013-05-12 15:05:23
     Zoe    4.12                     True                                  ''',

         '''\
id   Name   score                    isEnrolled                       Date
111  Jack   2.17                     True              2013-05-01 12:00:00
112  Nick   1.21                     False                                
     Zoe    4.12                     False             2013-05-01 12:00:00''']


df1 = pd.read_fwf(io.StringIO(texts[0]), widths=[5,7,25,17,20], parse_dates=[4])
df2 = pd.read_fwf(io.StringIO(texts[1]), widths=[5,7,25,17,20], parse_dates=[4])

定义你的diff函数…

def report_diff(x):
    return x[0] if x[0] == x[1] else '{} | {}'.format(*x)

然后你可以简单地使用Panel来总结:

my_panel = pd.Panel(dict(df1=df1,df2=df2))
print my_panel.apply(report_diff, axis=0)

#          id  Name        score    isEnrolled                       Date
#0        111  Jack   nan | 2.17          True        2013-05-01 12:00:00
#1        112  Nick  1.11 | 1.21         False  2013-05-12 15:05:23 | NaT
#2  nan | nan   Zoe         4.12  True | False  NaT | 2013-05-01 12:00:00

顺便说一下，如果你在IPython Notebook中，你可能喜欢使用彩色差异函数 根据单元格是否不同、相等或左/右为空来给出颜色:

from IPython.display import HTML
pd.options.display.max_colwidth = 500  # You need this, otherwise pandas
#                          will limit your HTML strings to 50 characters

def report_diff(x):
    if x[0]==x[1]:
        return unicode(x[0].__str__())
    elif pd.isnull(x[0]) and pd.isnull(x[1]):
        return u'<table style="background-color:#00ff00;font-weight:bold;">'+\
            '<tr><td>%s</td></tr><tr><td>%s</td></tr></table>' % ('nan', 'nan')
    elif pd.isnull(x[0]) and ~pd.isnull(x[1]):
        return u'<table style="background-color:#ffff00;font-weight:bold;">'+\
            '<tr><td>%s</td></tr><tr><td>%s</td></tr></table>' % ('nan', x[1])
    elif ~pd.isnull(x[0]) and pd.isnull(x[1]):
        return u'<table style="background-color:#0000ff;font-weight:bold;">'+\
            '<tr><td>%s</td></tr><tr><td>%s</td></tr></table>' % (x[0],'nan')
    else:
        return u'<table style="background-color:#ff0000;font-weight:bold;">'+\
            '<tr><td>%s</td></tr><tr><td>%s</td></tr></table>' % (x[0], x[1])

HTML(my_panel.apply(report_diff, axis=0).to_html(escape=False))

import pandas as pd
import io

texts = ['''\
id   Name   score                    isEnrolled                        Comment
111  Jack   2.17                     True                 He was late to class
112  Nick   1.11                     False                           Graduated
113  Zoe    4.12                     True       ''',

         '''\
id   Name   score                    isEnrolled                        Comment
111  Jack   2.17                     True                 He was late to class
112  Nick   1.21                     False                           Graduated
113  Zoe    4.12                     False                         On vacation''']


df1 = pd.read_fwf(io.StringIO(texts[0]), widths=[5,7,25,21,20])
df2 = pd.read_fwf(io.StringIO(texts[1]), widths=[5,7,25,21,20])
df = pd.concat([df1,df2]) 

print(df)
#     id  Name  score isEnrolled               Comment
# 0  111  Jack   2.17       True  He was late to class
# 1  112  Nick   1.11      False             Graduated
# 2  113   Zoe   4.12       True                   NaN
# 0  111  Jack   2.17       True  He was late to class
# 1  112  Nick   1.21      False             Graduated
# 2  113   Zoe   4.12      False           On vacation

df.set_index(['id', 'Name'], inplace=True)
print(df)
#           score isEnrolled               Comment
# id  Name                                        
# 111 Jack   2.17       True  He was late to class
# 112 Nick   1.11      False             Graduated
# 113 Zoe    4.12       True                   NaN
# 111 Jack   2.17       True  He was late to class
# 112 Nick   1.21      False             Graduated
# 113 Zoe    4.12      False           On vacation

def report_diff(x):
    return x[0] if x[0] == x[1] else '{} | {}'.format(*x)

changes = df.groupby(level=['id', 'Name']).agg(report_diff)
print(changes)

打印

                score    isEnrolled               Comment
id  Name                                                 
111 Jack         2.17          True  He was late to class
112 Nick  1.11 | 1.21         False             Graduated
113 Zoe          4.12  True | False     nan | On vacation

这个答案只是扩展了@Andy Hayden的答案，使其能够适应数值字段为nan的情况，并将其包装成一个函数。

import pandas as pd
import numpy as np


def diff_pd(df1, df2):
    """Identify differences between two pandas DataFrames"""
    assert (df1.columns == df2.columns).all(), \
        "DataFrame column names are different"
    if any(df1.dtypes != df2.dtypes):
        "Data Types are different, trying to convert"
        df2 = df2.astype(df1.dtypes)
    if df1.equals(df2):
        return None
    else:
        # need to account for np.nan != np.nan returning True
        diff_mask = (df1 != df2) & ~(df1.isnull() & df2.isnull())
        ne_stacked = diff_mask.stack()
        changed = ne_stacked[ne_stacked]
        changed.index.names = ['id', 'col']
        difference_locations = np.where(diff_mask)
        changed_from = df1.values[difference_locations]
        changed_to = df2.values[difference_locations]
        return pd.DataFrame({'from': changed_from, 'to': changed_to},
                            index=changed.index)

所以对于你的数据(稍微编辑一下，在分数列中有一个NaN):

import sys
if sys.version_info[0] < 3:
    from StringIO import StringIO
else:
    from io import StringIO

DF1 = StringIO("""id   Name   score                    isEnrolled           Comment
111  Jack   2.17                     True                 "He was late to class"
112  Nick   1.11                     False                "Graduated"
113  Zoe    NaN                     True                  " "
""")
DF2 = StringIO("""id   Name   score                    isEnrolled           Comment
111  Jack   2.17                     True                 "He was late to class"
112  Nick   1.21                     False                "Graduated"
113  Zoe    NaN                     False                "On vacation" """)
df1 = pd.read_table(DF1, sep='\s+', index_col='id')
df2 = pd.read_table(DF2, sep='\s+', index_col='id')
diff_pd(df1, df2)

输出:

                from           to
id  col                          
112 score       1.11         1.21
113 isEnrolled  True        False
    Comment           On vacation

在摆弄了@journois的答案后，由于Panel的弃用，我能够使用MultiIndex而不是Panel来工作。

首先，创建一些虚拟数据:

df1 = pd.DataFrame({
    'id': ['111', '222', '333', '444', '555'],
    'let': ['a', 'b', 'c', 'd', 'e'],
    'num': ['1', '2', '3', '4', '5']
})
df2 = pd.DataFrame({
    'id': ['111', '222', '333', '444', '666'],
    'let': ['a', 'b', 'c', 'D', 'f'],
    'num': ['1', '2', 'Three', '4', '6'],
})

然后，定义你的diff函数，在这种情况下，我将使用他的答案report_diff保持不变:

def report_diff(x):
    return x[0] if x[0] == x[1] else '{} | {}'.format(*x)

然后，我将数据连接到一个MultiIndex数据框架:

df_all = pd.concat(
    [df1.set_index('id'), df2.set_index('id')], 
    axis='columns', 
    keys=['df1', 'df2'],
    join='outer'
)
df_all = df_all.swaplevel(axis='columns')[df1.columns[1:]]

最后，我将对每个列组应用report_diff:

df_final.groupby(level=0, axis=1).apply(lambda frame: frame.apply(report_diff, axis=1))

这个输出:

         let        num
111        a          1
222        b          2
333        c  3 | Three
444    d | D          4
555  e | nan    5 | nan
666  nan | f    nan | 6

这就是全部!

第一部分类似于Constantine，你可以得到哪个行是空的布尔值*:

In [21]: ne = (df1 != df2).any(1)

In [22]: ne
Out[22]:
0    False
1     True
2     True
dtype: bool

然后我们可以看到哪些条目发生了变化:

In [23]: ne_stacked = (df1 != df2).stack()

In [24]: changed = ne_stacked[ne_stacked]

In [25]: changed.index.names = ['id', 'col']

In [26]: changed
Out[26]:
id  col
1   score         True
2   isEnrolled    True
    Comment       True
dtype: bool

这里的第一个条目是索引，第二个条目是已更改的列。

In [27]: difference_locations = np.where(df1 != df2)

In [28]: changed_from = df1.values[difference_locations]

In [29]: changed_to = df2.values[difference_locations]

In [30]: pd.DataFrame({'from': changed_from, 'to': changed_to}, index=changed.index)
Out[30]:
               from           to
id col
1  score       1.11         1.21
2  isEnrolled  True        False
   Comment     None  On vacation

*注意:重要的是df1和df2在这里共享相同的索引。为了克服这种模糊性，可以使用df1确保只查看共享标签。Index & df2。索引，但我还是把它留作练习吧。