扩展@cge的答案，这对于结果的可读性来说非常酷:

a[a != b][np.any(a != b, axis=1)].join(pd.DataFrame('a<->b', index=a.index, columns=['a<=>b'])).join(
        b[a != b][np.any(a != b, axis=1)]
        ,rsuffix='_b', how='outer'
).fillna('')

完整的演示示例:

import numpy as np, pandas as pd

a = pd.DataFrame(np.random.randn(7,3), columns=list('ABC'))
b = a.copy()
b.iloc[0,2] = np.nan
b.iloc[1,0] = 7
b.iloc[3,1] = 77
b.iloc[4,2] = 777

a[a != b][np.any(a != b, axis=1)].join(pd.DataFrame('a<->b', index=a.index, columns=['a<=>b'])).join(
        b[a != b][np.any(a != b, axis=1)]
        ,rsuffix='_b', how='outer'
).fillna('')

结果:样本

在线演示

使用concat和drop_duplicate的不同方法:

import sys
if sys.version_info[0] < 3:
    from StringIO import StringIO
else:
    from io import StringIO
import pandas as pd

DF1 = StringIO("""id   Name   score                    isEnrolled           Comment
111  Jack   2.17                     True                 "He was late to class"
112  Nick   1.11                     False                "Graduated"
113  Zoe    NaN                     True                  " "
""")
DF2 = StringIO("""id   Name   score                    isEnrolled           Comment
111  Jack   2.17                     True                 "He was late to class"
112  Nick   1.21                     False                "Graduated"
113  Zoe    NaN                     False                "On vacation" """)

df1 = pd.read_table(DF1, sep='\s+', index_col='id')
df2 = pd.read_table(DF2, sep='\s+', index_col='id')
#%%
dictionary = {1:df1,2:df2}
df=pd.concat(dictionary)
df.drop_duplicates(keep=False)

输出:

       Name  score isEnrolled      Comment
  id                                      
1 112  Nick   1.11      False    Graduated
  113   Zoe    NaN       True             
2 112  Nick   1.21      False    Graduated
  113   Zoe    NaN      False  On vacation

在摆弄了@journois的答案后，由于Panel的弃用，我能够使用MultiIndex而不是Panel来工作。

首先，创建一些虚拟数据:

df1 = pd.DataFrame({
    'id': ['111', '222', '333', '444', '555'],
    'let': ['a', 'b', 'c', 'd', 'e'],
    'num': ['1', '2', '3', '4', '5']
})
df2 = pd.DataFrame({
    'id': ['111', '222', '333', '444', '666'],
    'let': ['a', 'b', 'c', 'D', 'f'],
    'num': ['1', '2', 'Three', '4', '6'],
})

然后，定义你的diff函数，在这种情况下，我将使用他的答案report_diff保持不变:

def report_diff(x):
    return x[0] if x[0] == x[1] else '{} | {}'.format(*x)

然后，我将数据连接到一个MultiIndex数据框架:

df_all = pd.concat(
    [df1.set_index('id'), df2.set_index('id')], 
    axis='columns', 
    keys=['df1', 'df2'],
    join='outer'
)
df_all = df_all.swaplevel(axis='columns')[df1.columns[1:]]

最后，我将对每个列组应用report_diff:

df_final.groupby(level=0, axis=1).apply(lambda frame: frame.apply(report_diff, axis=1))

这个输出:

         let        num
111        a          1
222        b          2
333        c  3 | Three
444    d | D          4
555  e | nan    5 | nan
666  nan | f    nan | 6

这就是全部!

第一部分类似于Constantine，你可以得到哪个行是空的布尔值*:

In [21]: ne = (df1 != df2).any(1)

In [22]: ne
Out[22]:
0    False
1     True
2     True
dtype: bool

然后我们可以看到哪些条目发生了变化:

In [23]: ne_stacked = (df1 != df2).stack()

In [24]: changed = ne_stacked[ne_stacked]

In [25]: changed.index.names = ['id', 'col']

In [26]: changed
Out[26]:
id  col
1   score         True
2   isEnrolled    True
    Comment       True
dtype: bool

这里的第一个条目是索引，第二个条目是已更改的列。

In [27]: difference_locations = np.where(df1 != df2)

In [28]: changed_from = df1.values[difference_locations]

In [29]: changed_to = df2.values[difference_locations]

In [30]: pd.DataFrame({'from': changed_from, 'to': changed_to}, index=changed.index)
Out[30]:
               from           to
id col
1  score       1.11         1.21
2  isEnrolled  True        False
   Comment     None  On vacation

*注意:重要的是df1和df2在这里共享相同的索引。为了克服这种模糊性，可以使用df1确保只查看共享标签。Index & df2。索引，但我还是把它留作练习吧。

import pandas as pd
import io

texts = ['''\
id   Name   score                    isEnrolled                        Comment
111  Jack   2.17                     True                 He was late to class
112  Nick   1.11                     False                           Graduated
113  Zoe    4.12                     True       ''',

         '''\
id   Name   score                    isEnrolled                        Comment
111  Jack   2.17                     True                 He was late to class
112  Nick   1.21                     False                           Graduated
113  Zoe    4.12                     False                         On vacation''']


df1 = pd.read_fwf(io.StringIO(texts[0]), widths=[5,7,25,21,20])
df2 = pd.read_fwf(io.StringIO(texts[1]), widths=[5,7,25,21,20])
df = pd.concat([df1,df2]) 

print(df)
#     id  Name  score isEnrolled               Comment
# 0  111  Jack   2.17       True  He was late to class
# 1  112  Nick   1.11      False             Graduated
# 2  113   Zoe   4.12       True                   NaN
# 0  111  Jack   2.17       True  He was late to class
# 1  112  Nick   1.21      False             Graduated
# 2  113   Zoe   4.12      False           On vacation

df.set_index(['id', 'Name'], inplace=True)
print(df)
#           score isEnrolled               Comment
# id  Name                                        
# 111 Jack   2.17       True  He was late to class
# 112 Nick   1.11      False             Graduated
# 113 Zoe    4.12       True                   NaN
# 111 Jack   2.17       True  He was late to class
# 112 Nick   1.21      False             Graduated
# 113 Zoe    4.12      False           On vacation

def report_diff(x):
    return x[0] if x[0] == x[1] else '{} | {}'.format(*x)

changes = df.groupby(level=['id', 'Name']).agg(report_diff)
print(changes)

打印

                score    isEnrolled               Comment
id  Name                                                 
111 Jack         2.17          True  He was late to class
112 Nick  1.11 | 1.21         False             Graduated
113 Zoe          4.12  True | False     nan | On vacation

在两个数据帧之间寻找不对称差异的函数实现如下: (基于熊猫的集差) 要点:https://gist.github.com/oneryalcin/68cf25f536a25e65f0b3c84f9c118e03

def diff_df(df1, df2, how="left"):
    """
      Find Difference of rows for given two dataframes
      this function is not symmetric, means
            diff(x, y) != diff(y, x)
      however
            diff(x, y, how='left') == diff(y, x, how='right')

      Ref: https://stackoverflow.com/questions/18180763/set-difference-for-pandas/40209800#40209800
    """
    if (df1.columns != df2.columns).any():
        raise ValueError("Two dataframe columns must match")

    if df1.equals(df2):
        return None
    elif how == 'right':
        return pd.concat([df2, df1, df1]).drop_duplicates(keep=False)
    elif how == 'left':
        return pd.concat([df1, df2, df2]).drop_duplicates(keep=False)
    else:
        raise ValueError('how parameter supports only "left" or "right keywords"')

例子:

df1 = pd.DataFrame(d1)
Out[1]: 
                Comment  Name  isEnrolled  score
0  He was late to class  Jack        True   2.17
1             Graduated  Nick       False   1.11
2                         Zoe        True   4.12


df2 = pd.DataFrame(d2)

Out[2]: 
                Comment  Name  isEnrolled  score
0  He was late to class  Jack        True   2.17
1           On vacation   Zoe        True   4.12

diff_df(df1, df2)
Out[3]: 
     Comment  Name  isEnrolled  score
1  Graduated  Nick       False   1.11
2              Zoe        True   4.12

diff_df(df2, df1)
Out[4]: 
       Comment Name  isEnrolled  score
1  On vacation  Zoe        True   4.12

# This gives the same result as above
diff_df(df1, df2, how='right')
Out[22]: 
       Comment Name  isEnrolled  score
1  On vacation  Zoe        True   4.12