使用线程池是一个很好的选择，这将使这相当容易。不幸的是，python并没有一个标准库来简化线程池。但这里有一个不错的图书馆，你应该开始: http://www.chrisarndt.de/projects/threadpool/

来自他们网站的代码示例:

pool = ThreadPool(poolsize)
requests = makeRequests(some_callable, list_of_args, callback)
[pool.putRequest(req) for req in requests]
pool.wait()

希望这能有所帮助。

如果您希望获得尽可能好的性能，您可能会考虑使用异步I/O而不是线程。与成千上万个操作系统线程相关的开销是不小的，Python解释器内的上下文切换甚至增加了更多的开销。线程当然可以完成工作，但我怀疑异步路由将提供更好的整体性能。

具体来说，我建议使用Twisted库中的异步web客户端(http://www.twistedmatrix.com)。它有一个公认的陡峭的学习曲线，但一旦你很好地掌握了Twisted的异步编程风格，它就很容易使用。

Twisted的异步web客户端API的HowTo可以在以下地址找到:

http://twistedmatrix.com/documents/current/web/howto/client.html

我知道这是一个老问题，但在Python 3.7中，您可以使用asyncio和aiohttp来做到这一点。

import asyncio
import aiohttp
from aiohttp import ClientSession, ClientConnectorError

async def fetch_html(url: str, session: ClientSession, **kwargs) -> tuple:
    try:
        resp = await session.request(method="GET", url=url, **kwargs)
    except ClientConnectorError:
        return (url, 404)
    return (url, resp.status)

async def make_requests(urls: set, **kwargs) -> None:
    async with ClientSession() as session:
        tasks = []
        for url in urls:
            tasks.append(
                fetch_html(url=url, session=session, **kwargs)
            )
        results = await asyncio.gather(*tasks)

    for result in results:
        print(f'{result[1]} - {str(result[0])}')

if __name__ == "__main__":
    import pathlib
    import sys

    assert sys.version_info >= (3, 7), "Script requires Python 3.7+."
    here = pathlib.Path(__file__).parent

    with open(here.joinpath("urls.txt")) as infile:
        urls = set(map(str.strip, infile))

    asyncio.run(make_requests(urls=urls))

你可以阅读更多关于它的内容，并在这里看到一个例子。

对于您的情况，线程可能会做的技巧，因为您可能会花费大部分时间等待响应。标准库中有一些有用的模块，如Queue，可能会有所帮助。

我以前做过类似的并行下载文件的事情，对我来说已经足够好了，但它不是你所说的那种规模。

如果您的任务对cpu的限制更大，您可能需要考虑multiprocessing模块，它将允许您利用更多的cpu /内核/线程(更多的进程不会相互阻塞，因为锁定是每个进程)

(下一个项目的自我提示)

Python 3解决方案只使用请求。它是最简单且快速的，不需要多处理或复杂的异步库。

最重要的方面是重用连接，特别是对于HTTPS (TLS需要额外的往返才能打开)。注意，连接是特定于子域的。如果在多个域上抓取多个页面，则可以对url列表进行排序，以最大化连接重用(它有效地按域进行排序)。

当给定足够的线程时，它将与任何异步代码一样快。(请求在等待响应时释放python GIL)。

[带有日志记录和错误处理的生产等级代码]

import logging
import requests
import time
from concurrent.futures import ThreadPoolExecutor, as_completed

# source: https://stackoverflow.com/a/68583332/5994461

THREAD_POOL = 16

# This is how to create a reusable connection pool with python requests.
session = requests.Session()
session.mount(
    'https://',
    requests.adapters.HTTPAdapter(pool_maxsize=THREAD_POOL,
                                  max_retries=3,
                                  pool_block=True)
)

def get(url):
    response = session.get(url)
    logging.info("request was completed in %s seconds [%s]", response.elapsed.total_seconds(), response.url)
    if response.status_code != 200:
        logging.error("request failed, error code %s [%s]", response.status_code, response.url)
    if 500 <= response.status_code < 600:
        # server is overloaded? give it a break
        time.sleep(5)
    return response

def download(urls):
    with ThreadPoolExecutor(max_workers=THREAD_POOL) as executor:
        # wrap in a list() to wait for all requests to complete
        for response in list(executor.map(get, urls)):
            if response.status_code == 200:
                print(response.content)

def main():
    logging.basicConfig(
        format='%(asctime)s.%(msecs)03d %(levelname)-8s %(message)s',
        level=logging.INFO,
        datefmt='%Y-%m-%d %H:%M:%S'
    )

    urls = [
        "https://httpstat.us/200",
        "https://httpstat.us/200",
        "https://httpstat.us/200",
        "https://httpstat.us/404",
        "https://httpstat.us/503"
    ]

    download(urls)

if __name__ == "__main__":
    main()

这个扭曲的异步web客户端运行得相当快。

#!/usr/bin/python2.7

from twisted.internet import reactor
from twisted.internet.defer import Deferred, DeferredList, DeferredLock
from twisted.internet.defer import inlineCallbacks
from twisted.web.client import Agent, HTTPConnectionPool
from twisted.web.http_headers import Headers
from pprint import pprint
from collections import defaultdict
from urlparse import urlparse
from random import randrange
import fileinput

pool = HTTPConnectionPool(reactor)
pool.maxPersistentPerHost = 16
agent = Agent(reactor, pool)
locks = defaultdict(DeferredLock)
codes = {}

def getLock(url, simultaneous = 1):
    return locks[urlparse(url).netloc, randrange(simultaneous)]

@inlineCallbacks
def getMapping(url):
    # Limit ourselves to 4 simultaneous connections per host
    # Tweak this number, but it should be no larger than pool.maxPersistentPerHost 
    lock = getLock(url,4)
    yield lock.acquire()
    try:
        resp = yield agent.request('HEAD', url)
        codes[url] = resp.code
    except Exception as e:
        codes[url] = str(e)
    finally:
        lock.release()


dl = DeferredList(getMapping(url.strip()) for url in fileinput.input())
dl.addCallback(lambda _: reactor.stop())

reactor.run()
pprint(codes)