更新(5/5/16):应该使用patriques的答案，因为它既简单又可靠。

Since the canvas isn't always styled relative to the entire page, the canvas.offsetLeft/Top doesn't always return what you need. It will return the number of pixels it is offset relative to its offsetParent element, which can be something like a div element containing the canvas with a position: relative style applied. To account for this you need to loop through the chain of offsetParents, beginning with the canvas element itself. This code works perfectly for me, tested in Firefox and Safari but should work for all.

function relMouseCoords(event){
    var totalOffsetX = 0;
    var totalOffsetY = 0;
    var canvasX = 0;
    var canvasY = 0;
    var currentElement = this;

    do{
        totalOffsetX += currentElement.offsetLeft - currentElement.scrollLeft;
        totalOffsetY += currentElement.offsetTop - currentElement.scrollTop;
    }
    while(currentElement = currentElement.offsetParent)

    canvasX = event.pageX - totalOffsetX;
    canvasY = event.pageY - totalOffsetY;

    return {x:canvasX, y:canvasY}
}
HTMLCanvasElement.prototype.relMouseCoords = relMouseCoords;

最后一行可以方便地获取相对于canvas元素的鼠标坐标。要得到有用的坐标只需要

coords = canvas.relMouseCoords(event);
canvasX = coords.x;
canvasY = coords.y;

我做了一个完整的演示，可以在每个浏览器中使用这个问题的解决方案的完整源代码:在Javascript中单击Canvas的鼠标坐标。要尝试演示，复制代码并将其粘贴到文本编辑器中。然后将其保存为example.html，最后用浏览器打开该文件。

根据最新的Quirksmode，所有主流浏览器都支持clientX和clientY方法。 所以，它开始了-在滚动条页面上的滚动div中工作的良好工作代码:

function getCursorPosition(canvas, event) {
var x, y;

canoffset = $(canvas).offset();
x = event.clientX + document.body.scrollLeft + document.documentElement.scrollLeft - Math.floor(canoffset.left);
y = event.clientY + document.body.scrollTop + document.documentElement.scrollTop - Math.floor(canoffset.top) + 1;

return [x,y];
}

这也需要jQuery $(canvas).offset()。

我推荐这个链接 http://miloq.blogspot.in/2011/05/coordinates-mouse-click-canvas.html

<style type="text/css">

  #canvas{background-color: #000;}

</style>

<script type="text/javascript">

  document.addEventListener("DOMContentLoaded", init, false);

  function init()
  {
    var canvas = document.getElementById("canvas");
    canvas.addEventListener("mousedown", getPosition, false);
  }

  function getPosition(event)
  {
    var x = new Number();
    var y = new Number();
    var canvas = document.getElementById("canvas");

    if (event.x != undefined && event.y != undefined)
    {
      x = event.x;
      y = event.y;
    }
    else // Firefox method to get the position
    {
      x = event.clientX + document.body.scrollLeft +
          document.documentElement.scrollLeft;
      y = event.clientY + document.body.scrollTop +
          document.documentElement.scrollTop;
    }

    x -= canvas.offsetLeft;
    y -= canvas.offsetTop;

    alert("x: " + x + "  y: " + y);
  }

</script>

下面是对Ryan Artecona关于画布宽度可变(%)的答案的一个小修改:

 HTMLCanvasElement.prototype.relMouseCoords = function (event) {
    var totalOffsetX = 0;
    var totalOffsetY = 0;
    var canvasX = 0;
    var canvasY = 0;
    var currentElement = this;

    do {
        totalOffsetX += currentElement.offsetLeft;
        totalOffsetY += currentElement.offsetTop;
    }
    while (currentElement = currentElement.offsetParent)

    canvasX = event.pageX - totalOffsetX;
    canvasY = event.pageY - totalOffsetY;

    // Fix for variable canvas width
    canvasX = Math.round( canvasX * (this.width / this.offsetWidth) );
    canvasY = Math.round( canvasY * (this.height / this.offsetHeight) );

    return {x:canvasX, y:canvasY}
}

以下是上述Ryan Artecona解决方案的一些修改。

function myGetPxStyle(e,p)
{
    var r=window.getComputedStyle?window.getComputedStyle(e,null)[p]:"";
    return parseFloat(r);
}

function myGetClick=function(ev)
{
    // {x:ev.layerX,y:ev.layerY} doesn't work when zooming with mac chrome 27
    // {x:ev.clientX,y:ev.clientY} not supported by mac firefox 21
    // document.body.scrollLeft and document.body.scrollTop seem required when scrolling on iPad
    // html is not an offsetParent of body but can have non null offsetX or offsetY (case of wordpress 3.5.1 admin pages for instance)
    // html.offsetX and html.offsetY don't work with mac firefox 21

    var offsetX=0,offsetY=0,e=this,x,y;
    var htmls=document.getElementsByTagName("html"),html=(htmls?htmls[0]:0);

    do
    {
        offsetX+=e.offsetLeft-e.scrollLeft;
        offsetY+=e.offsetTop-e.scrollTop;
    } while (e=e.offsetParent);

    if (html)
    {
        offsetX+=myGetPxStyle(html,"marginLeft");
        offsetY+=myGetPxStyle(html,"marginTop");
    }

    x=ev.pageX-offsetX-document.body.scrollLeft;
    y=ev.pageY-offsetY-document.body.scrollTop;
    return {x:x,y:y};
}