这里已经有了一些很好的答案。根据mdsharpe的建议，这里有一个扩展方法，当您想处理Uri实例时可以轻松使用：

using System;
using System.Linq;

public static class UriExtensions
{
    public static Uri Append(this Uri uri, params string[] paths)
    {
        return new Uri(paths.Aggregate(uri.AbsoluteUri, (current, path) => string.Format("{0}/{1}", current.TrimEnd('/'), path.TrimStart('/'))));
    }
}

使用示例：

var url = new Uri("http://example.com/subpath/").Append("/part1/", "part2").AbsoluteUri;

这将产生http://example.com/subpath/part1/part2

如果您希望使用字符串而不是Uris，那么以下操作也会产生相同的结果，只需根据您的需要进行调整即可：

public string JoinUriSegments(string uri, params string[] segments)
{
    if (string.IsNullOrWhiteSpace(uri))
        return null;

    if (segments == null || segments.Length == 0)
        return uri;

    return segments.Aggregate(uri, (current, segment) => $"{current.TrimEnd('/')}/{segment.TrimStart('/')}");
}

var uri = JoinUriSegements("http://example.com/subpath/", "/part1/", "part2");

Path.Combine("Http://MyUrl.com/", "/Images/Image.jpg").Replace("\\", "/")

Uri有一个构造函数可以为您执行此操作：new Uri（Uri baseUri，string relativeUri）

下面是一个示例：

Uri baseUri = new Uri("http://www.contoso.com");
Uri myUri = new Uri(baseUri, "catalog/shownew.htm");

编辑注意：小心，这种方法并不能像预期的那样工作。在某些情况下，它可以剪切baseUri的一部分。查看评论和其他答案。

我创建了这个功能，可以让您的生活更轻松：

    /// <summary>
    /// The ultimate Path combiner of all time
    /// </summary>
    /// <param name="IsURL">
    /// true - if the paths are Internet URLs, false - if the paths are local URLs, this is very important as this will be used to decide which separator will be used.
    /// </param>
    /// <param name="IsRelative">Just adds the separator at the beginning</param>
    /// <param name="IsFixInternal">Fix the paths from within (by removing duplicate separators and correcting the separators)</param>
    /// <param name="parts">The paths to combine</param>
    /// <returns>the combined path</returns>
    public static string PathCombine(bool IsURL , bool IsRelative , bool IsFixInternal , params string[] parts)
    {
        if (parts == null || parts.Length == 0) return string.Empty;
        char separator = IsURL ? '/' : '\\';

        if (parts.Length == 1 && IsFixInternal)
        {
            string validsingle;
            if (IsURL)
            {
                validsingle = parts[0].Replace('\\' , '/');
            }
            else
            {
                validsingle = parts[0].Replace('/' , '\\');
            }
            validsingle = validsingle.Trim(separator);
            return (IsRelative ? separator.ToString() : string.Empty) + validsingle;
        }

        string final = parts
            .Aggregate
            (
            (string first , string second) =>
            {
                string validfirst;
                string validsecond;
                if (IsURL)
                {
                    validfirst = first.Replace('\\' , '/');
                    validsecond = second.Replace('\\' , '/');
                }
                else
                {
                    validfirst = first.Replace('/' , '\\');
                    validsecond = second.Replace('/' , '\\');
                }
                var prefix = string.Empty;
                if (IsFixInternal)
                {
                    if (IsURL)
                    {
                        if (validfirst.Contains("://"))
                        {
                            var tofix = validfirst.Substring(validfirst.IndexOf("://") + 3);
                            prefix = validfirst.Replace(tofix , string.Empty).TrimStart(separator);

                            var tofixlist = tofix.Split(new[] { separator } , StringSplitOptions.RemoveEmptyEntries);

                            validfirst = separator + string.Join(separator.ToString() , tofixlist);
                        }
                        else
                        {
                            var firstlist = validfirst.Split(new[] { separator } , StringSplitOptions.RemoveEmptyEntries);
                            validfirst = string.Join(separator.ToString() , firstlist);
                        }

                        var secondlist = validsecond.Split(new[] { separator } , StringSplitOptions.RemoveEmptyEntries);
                        validsecond = string.Join(separator.ToString() , secondlist);
                    }
                    else
                    {
                        var firstlist = validfirst.Split(new[] { separator } , StringSplitOptions.RemoveEmptyEntries);
                        var secondlist = validsecond.Split(new[] { separator } , StringSplitOptions.RemoveEmptyEntries);

                        validfirst = string.Join(separator.ToString() , firstlist);
                        validsecond = string.Join(separator.ToString() , secondlist);
                    }
                }
                return prefix + validfirst.Trim(separator) + separator + validsecond.Trim(separator);
            }
            );
        return (IsRelative ? separator.ToString() : string.Empty) + final;
    }

它适用于URL和普通路径。

用法：

    // Fixes internal paths
    Console.WriteLine(PathCombine(true , true , true , @"\/\/folder 1\/\/\/\\/\folder2\///folder3\\/" , @"/\somefile.ext\/\//\"));
    // Result: /folder 1/folder2/folder3/somefile.ext

    // Doesn't fix internal paths
    Console.WriteLine(PathCombine(true , true , false , @"\/\/folder 1\/\/\/\\/\folder2\///folder3\\/" , @"/\somefile.ext\/\//\"));
    //result : /folder 1//////////folder2////folder3/somefile.ext

    // Don't worry about URL prefixes when fixing internal paths
    Console.WriteLine(PathCombine(true , false , true , @"/\/\/https:/\/\/\lul.com\/\/\/\\/\folder2\///folder3\\/" , @"/\somefile.ext\/\//\"));
    // Result: https://lul.com/folder2/folder3/somefile.ext

    Console.WriteLine(PathCombine(false , true , true , @"../../../\\..\...\./../somepath" , @"anotherpath"));
    // Result: \..\..\..\..\...\.\..\somepath\anotherpath

将URL与URI组合时的规则

为了避免奇怪的行为，需要遵循一条规则：

路径（目录）必须以“/”结尾。如果路径结尾不带“/”，则最后一部分将被视为文件名，并且在尝试与下一个URL部分组合时将被连接。有一个例外：基本URL地址（没有目录信息）不需要以“/”结尾路径部分不能以“/”开头。如果它以“/”开头，则URL中的所有现有相关信息都将被删除。。。添加字符串。空的部分路径也会从URL中删除相对目录！

如果您遵循上面的规则，您可以将URL与下面的代码组合。根据您的情况，您可以向URL添加多个“目录”部分。。。

        var pathParts = new string[] { destinationBaseUrl, destinationFolderUrl, fileName };

        var destination = pathParts.Aggregate((left, right) =>
        {
            if (string.IsNullOrWhiteSpace(right))
                return left;

            return new Uri(new Uri(left), right).ToString();
        });

我必须指出，Path.Combine似乎也能直接实现这一点，至少在.NET 4上是如此。