“la”Scala方式（但我认为这是OP要求的最具Python风格的方式）：

description = """
            | The intention of this module is to provide a method to
            | pass meta information in markdown_ header files for
            | using it in jinja_ templates.
            |
            | Also, to provide a method to use markdown files as jinja
            | templates. Maybe you prefer to see the code than
            | to install it.""".replace('\n            | \n','\n').replace('            | ',' ')

如果您希望最后的str没有跳转行，只需将\n放在第二个替换的第一个参数的开头：

.replace('\n            | ',' ')`.

注意：“…templates.”和“另外，…”之间的白线需要在|后面加一个空格。

我认为当代码（例如，变量）缩进并且输出字符串应该是单行（没有换行）时，另一个选项更可读：

def some_method():

    long_string = """
A presumptuous long string
which looks a bit nicer
in a text editor when
written over multiple lines
""".strip('\n').replace('\n', ' ')

    return long_string

嗯。

我知道这个问题发布已经很久了。但我刚刚找到了我想用来为项目中的变量分配长字符串和多行字符串的样式。这需要一点额外的运行时间，但仍然保留了代码的美感，即使我将字符串分配给的变量缩进很大。

    # Suppose the following code is heavily indented
    line3header = "Third"

    variable = fr"""

First line.
Second line.
{line3header} line.
{{}} line.
...
The last line.

    """.strip()
    """A variable whose name is Variable.

    You can even add a docstring here.
    """

    variable = variable.format("Fourth")
    print(variable)
    variable += "\n"
    print(variable, end="")

就这样。

为了在字典内定义长字符串，保留换行符但省略空格，我最终以如下常量定义字符串：

LONG_STRING = \
"""
This is a long sting
that contains newlines.
The newlines are important.
"""

my_dict = {
   'foo': 'bar',
   'string': LONG_STRING
}

该方法使用：

使用三引号字符串几乎没有内部标点符号使用检查模块去除局部压痕account_id和def_id变量使用Python 3.6格式的字符串插值（'f'）。

这种方式在我看来是最有蟒蛇风格的。

import inspect

query = inspect.cleandoc(f'''
    SELECT action.descr as "action",
    role.id as role_id,
    role.descr as role
    FROM
    public.role_action_def,
    public.role,
    public.record_def,
    public.action
    WHERE role.id = role_action_def.role_id AND
    record_def.id = role_action_def.def_id AND
    action.id = role_action_def.action_id AND
    role_action_def.account_id = {account_id} AND
    record_def.account_id={account_id} AND
    def_id={def_id}'''
)

我通常用这样的词：

text = '''
    This string was typed to be a demo
    on how could we write a multi-line
    text in Python.
'''

如果要删除每行中烦人的空格，可以执行以下操作：

text = '\n'.join(line.lstrip() for line in text.splitlines())