我认为这取决于你想做什么，你的问题没有详细说明。

对我来说，我想在一个已经多线程的进程中做一个昂贵的操作。所以我让leader流程检查时间，只有她做昂贵的操作(检查点深度学习模型)。为了做到这一点，我增加了计数器，以确保5秒、10秒、15秒过去，每5秒保存一次(或使用math.floor的模块化算术):

def print_every_5_seconds_have_passed_exit_eventually():
    """
    https://stackoverflow.com/questions/3393612/run-certain-code-every-n-seconds
    https://stackoverflow.com/questions/474528/what-is-the-best-way-to-repeatedly-execute-a-function-every-x-seconds
    :return:
    """
    opts = argparse.Namespace(start=time.time())
    next_time_to_print = 0
    while True:
        current_time_passed = time.time() - opts.start
        if current_time_passed >= next_time_to_print:
            next_time_to_print += 5
            print(f'worked and {current_time_passed=}')
            print(f'{current_time_passed % 5=}')
            print(f'{math.floor(current_time_passed % 5) == 0}')

starting __main__ at __init__
worked and current_time_passed=0.0001709461212158203
current_time_passed % 5=0.0001709461212158203
True
worked and current_time_passed=5.0
current_time_passed % 5=0.0
True
worked and current_time_passed=10.0
current_time_passed % 5=0.0
True
worked and current_time_passed=15.0
current_time_passed % 5=0.0
True

对我来说，检查if语句是我所需要的。在我已经复杂的多处理器多gpu代码中拥有线程，调度器并不是我想要添加的复杂性，如果我可以避免它，似乎我可以。检查worker id很容易确保只有一个进程在做这件事。

注意，我使用True print语句来确保模块化的算术技巧有效，因为检查确切的时间显然是行不通的!但令我惊喜的是，地板竟然起了作用。

我最终使用了时间表模块。API很好。

import schedule
import time

def job():
    print("I'm working...")

schedule.every(10).minutes.do(job)
schedule.every().hour.do(job)
schedule.every().day.at("10:30").do(job)
schedule.every(5).to(10).minutes.do(job)
schedule.every().monday.do(job)
schedule.every().wednesday.at("13:15").do(job)
schedule.every().minute.at(":17").do(job)

while True:
    schedule.run_pending()
    time.sleep(1)

它和cron之间的主要区别是异常会永久地杀死守护进程。您可能希望使用异常捕获器和记录器进行包装。

import time, traceback

def every(delay, task):
  next_time = time.time() + delay
  while True:
    time.sleep(max(0, next_time - time.time()))
    try:
      task()
    except Exception:
      traceback.print_exc()
      # in production code you might want to have this instead of course:
      # logger.exception("Problem while executing repetitive task.")
    # skip tasks if we are behind schedule:
    next_time += (time.time() - next_time) // delay * delay + delay

def foo():
  print("foo", time.time())

every(5, foo)

如果你想在不阻塞剩余代码的情况下这样做，你可以使用这个让它在自己的线程中运行:

import threading
threading.Thread(target=lambda: every(5, foo)).start()

该解决方案结合了其他解决方案中很少结合的几个特性:

Exception handling: As far as possible on this level, exceptions are handled properly, i. e. get logged for debugging purposes without aborting our program. No chaining: The common chain-like implementation (for scheduling the next event) you find in many answers is brittle in the aspect that if anything goes wrong within the scheduling mechanism (threading.Timer or whatever), this will terminate the chain. No further executions will happen then, even if the reason of the problem is already fixed. A simple loop and waiting with a simple sleep() is much more robust in comparison. No drift: My solution keeps an exact track of the times it is supposed to run at. There is no drift depending on the execution time (as in many other solutions). Skipping: My solution will skip tasks if one execution took too much time (e. g. do X every five seconds, but X took 6 seconds). This is the standard cron behavior (and for a good reason). Many other solutions then simply execute the task several times in a row without any delay. For most cases (e. g. cleanup tasks) this is not wished. If it is wished, simply use next_time += delay instead.

我使用Tkinter after()方法，它不会“窃取游戏”(就像之前提出的sched模块)，即它允许其他东西并行运行:

import Tkinter

def do_something1():
  global n1
  n1 += 1
  if n1 == 6: # (Optional condition)
    print "* do_something1() is done *"; return
  # Do your stuff here
  # ...
  print "do_something1() "+str(n1)
  tk.after(1000, do_something1)

def do_something2(): 
  global n2
  n2 += 1
  if n2 == 6: # (Optional condition)
    print "* do_something2() is done *"; return
  # Do your stuff here
  # ...
  print "do_something2() "+str(n2)
  tk.after(500, do_something2)

tk = Tkinter.Tk(); 
n1 = 0; n2 = 0
do_something1()
do_something2()
tk.mainloop()

Do_something1()和do_something2()可以以任意的间隔速度并行运行。在这里，第2个将以两倍的速度执行。还要注意，我使用了一个简单的计数器作为终止任一函数的条件。你可以使用任何你喜欢的条件，或者不使用，如果你想让一个函数运行到程序终止(例如一个时钟)。

下面是MestreLion对代码的更新，它可以避免随着时间的推移而漂移。

这里的RepeatedTimer类按照OP的请求每隔“间隔”秒调用给定函数;调度并不取决于函数执行的时间。我喜欢这个解决方案，因为它没有外部库依赖关系;这是纯python。

import threading 
import time

class RepeatedTimer(object):
  def __init__(self, interval, function, *args, **kwargs):
    self._timer = None
    self.interval = interval
    self.function = function
    self.args = args
    self.kwargs = kwargs
    self.is_running = False
    self.next_call = time.time()
    self.start()

  def _run(self):
    self.is_running = False
    self.start()
    self.function(*self.args, **self.kwargs)

  def start(self):
    if not self.is_running:
      self.next_call += self.interval
      self._timer = threading.Timer(self.next_call - time.time(), self._run)
      self._timer.start()
      self.is_running = True

  def stop(self):
    self._timer.cancel()
    self.is_running = False

示例用法(摘自MestreLion的回答):

from time import sleep

def hello(name):
    print "Hello %s!" % name

print "starting..."
rt = RepeatedTimer(1, hello, "World") # it auto-starts, no need of rt.start()
try:
    sleep(5) # your long-running job goes here...
finally:
    rt.stop() # better in a try/finally block to make sure the program ends!