现有的解决方案不适合我(详情见下文)。最后成功的是使用read(1)实现readline(基于这个答案)。后者不阻塞:

from subprocess import Popen, PIPE
from threading import Thread
def process_output(myprocess): #output-consuming thread
    nextline = None
    buf = ''
    while True:
        #--- extract line using read(1)
        out = myprocess.stdout.read(1)
        if out == '' and myprocess.poll() != None: break
        if out != '':
            buf += out
            if out == '\n':
                nextline = buf
                buf = ''
        if not nextline: continue
        line = nextline
        nextline = None

        #--- do whatever you want with line here
        print 'Line is:', line
    myprocess.stdout.close()

myprocess = Popen('myprogram.exe', stdout=PIPE) #output-producing process
p1 = Thread(target=process_output, args=(myprocess,)) #output-consuming thread
p1.daemon = True
p1.start()

#--- do whatever here and then kill process and thread if needed
if myprocess.poll() == None: #kill process; will automatically stop thread
    myprocess.kill()
    myprocess.wait()
if p1 and p1.is_alive(): #wait for thread to finish
    p1.join()

为什么现有的解决方案不起作用:

Solutions that require readline (including the Queue based ones) always block. It is difficult (impossible?) to kill the thread that executes readline. It only gets killed when the process that created it finishes, but not when the output-producing process is killed. Mixing low-level fcntl with high-level readline calls may not work properly as anonnn has pointed out. Using select.poll() is neat, but doesn't work on Windows according to python docs. Using third-party libraries seems overkill for this task and adds additional dependencies.

在现代Python中，情况要好得多。

下面是一个简单的子程序"hello.py":

#!/usr/bin/env python3

while True:
    i = input()
    if i == "quit":
        break
    print(f"hello {i}")

以及一个与之交互的程序:

import asyncio


async def main():
    proc = await asyncio.subprocess.create_subprocess_exec(
        "./hello.py", stdin=asyncio.subprocess.PIPE, stdout=asyncio.subprocess.PIPE
    )
    proc.stdin.write(b"bob\n")
    print(await proc.stdout.read(1024))
    proc.stdin.write(b"alice\n")
    print(await proc.stdout.read(1024))
    proc.stdin.write(b"quit\n")
    await proc.wait()


asyncio.run(main())

打印出来:

b'hello bob\n'
b'hello alice\n'

请注意，实际的模式(几乎所有前面的回答，包括这里和相关的问题)是将子进程的stdout文件描述符设置为非阻塞，然后在某种选择循环中轮询它。当然，现在这个循环是由asyncio提供的。

试试asyncproc模块。例如:

import os
from asyncproc import Process
myProc = Process("myprogram.app")

while True:
    # check to see if process has ended
    poll = myProc.wait(os.WNOHANG)
    if poll != None:
        break
    # print any new output
    out = myProc.read()
    if out != "":
        print out

该模块负责S.Lott建议的所有线程。

在我的例子中，我需要一个日志模块来捕获后台应用程序的输出并对其进行扩充(添加时间戳、颜色等)。

我最终使用了一个后台线程来执行实际的I/O操作。以下代码仅适用于POSIX平台。我去掉了不重要的部分。

如果有人打算长期使用这个野兽，可以考虑管理开放描述符。对我来说，这不是什么大问题。

# -*- python -*-
import fcntl
import threading
import sys, os, errno
import subprocess

class Logger(threading.Thread):
    def __init__(self, *modules):
        threading.Thread.__init__(self)
        try:
            from select import epoll, EPOLLIN
            self.__poll = epoll()
            self.__evt = EPOLLIN
            self.__to = -1
        except:
            from select import poll, POLLIN
            print 'epoll is not available'
            self.__poll = poll()
            self.__evt = POLLIN
            self.__to = 100
        self.__fds = {}
        self.daemon = True
        self.start()

    def run(self):
        while True:
            events = self.__poll.poll(self.__to)
            for fd, ev in events:
                if (ev&self.__evt) != self.__evt:
                    continue
                try:
                    self.__fds[fd].run()
                except Exception, e:
                    print e

    def add(self, fd, log):
        assert not self.__fds.has_key(fd)
        self.__fds[fd] = log
        self.__poll.register(fd, self.__evt)

class log:
    logger = Logger()

    def __init__(self, name):
        self.__name = name
        self.__piped = False

    def fileno(self):
        if self.__piped:
            return self.write
        self.read, self.write = os.pipe()
        fl = fcntl.fcntl(self.read, fcntl.F_GETFL)
        fcntl.fcntl(self.read, fcntl.F_SETFL, fl | os.O_NONBLOCK)
        self.fdRead = os.fdopen(self.read)
        self.logger.add(self.read, self)
        self.__piped = True
        return self.write

    def __run(self, line):
        self.chat(line, nl=False)

    def run(self):
        while True:
            try: line = self.fdRead.readline()
            except IOError, exc:
                if exc.errno == errno.EAGAIN:
                    return
                raise
            self.__run(line)

    def chat(self, line, nl=True):
        if nl: nl = '\n'
        else: nl = ''
        sys.stdout.write('[%s] %s%s' % (self.__name, line, nl))

def system(command, param=[], cwd=None, env=None, input=None, output=None):
    args = [command] + param
    p = subprocess.Popen(args, cwd=cwd, stdout=output, stderr=output, stdin=input, env=env, bufsize=0)
    p.wait()

ls = log('ls')
ls.chat('go')
system("ls", ['-l', '/'], output=ls)

date = log('date')
date.chat('go')
system("date", output=date)

下面是我的代码，用于捕获子进程ASAP的每个输出，包括部分行。它同时泵浦，stdout和stderr的顺序几乎是正确的。

在Python 2.7 linux和windows上测试并正确工作。

#!/usr/bin/python
#
# Runner with stdout/stderr catcher
#
from sys import argv
from subprocess import Popen, PIPE
import os, io
from threading import Thread
import Queue
def __main__():
    if (len(argv) > 1) and (argv[-1] == "-sub-"):
        import time, sys
        print "Application runned!"
        time.sleep(2)
        print "Slept 2 second"
        time.sleep(1)
        print "Slept 1 additional second",
        time.sleep(2)
        sys.stderr.write("Stderr output after 5 seconds")
        print "Eol on stdin"
        sys.stderr.write("Eol on stderr\n")
        time.sleep(1)
        print "Wow, we have end of work!",
    else:
        os.environ["PYTHONUNBUFFERED"]="1"
        try:
            p = Popen( argv + ["-sub-"],
                       bufsize=0, # line-buffered
                       stdin=PIPE, stdout=PIPE, stderr=PIPE )
        except WindowsError, W:
            if W.winerror==193:
                p = Popen( argv + ["-sub-"],
                           shell=True, # Try to run via shell
                           bufsize=0, # line-buffered
                           stdin=PIPE, stdout=PIPE, stderr=PIPE )
            else:
                raise
        inp = Queue.Queue()
        sout = io.open(p.stdout.fileno(), 'rb', closefd=False)
        serr = io.open(p.stderr.fileno(), 'rb', closefd=False)
        def Pump(stream, category):
            queue = Queue.Queue()
            def rdr():
                while True:
                    buf = stream.read1(8192)
                    if len(buf)>0:
                        queue.put( buf )
                    else:
                        queue.put( None )
                        return
            def clct():
                active = True
                while active:
                    r = queue.get()
                    try:
                        while True:
                            r1 = queue.get(timeout=0.005)
                            if r1 is None:
                                active = False
                                break
                            else:
                                r += r1
                    except Queue.Empty:
                        pass
                    inp.put( (category, r) )
            for tgt in [rdr, clct]:
                th = Thread(target=tgt)
                th.setDaemon(True)
                th.start()
        Pump(sout, 'stdout')
        Pump(serr, 'stderr')

        while p.poll() is None:
            # App still working
            try:
                chan,line = inp.get(timeout = 1.0)
                if chan=='stdout':
                    print "STDOUT>>", line, "<?<"
                elif chan=='stderr':
                    print " ERROR==", line, "=?="
            except Queue.Empty:
                pass
        print "Finish"

if __name__ == '__main__':
    __main__()

这是一个在子进程中执行交互命令的例子，通过伪终端实现了stdout的交互。您可以参考:https://stackoverflow.com/a/43012138/3555925

#!/usr/bin/env python
# -*- coding: utf-8 -*-

import os
import sys
import select
import termios
import tty
import pty
from subprocess import Popen

command = 'bash'
# command = 'docker run -it --rm centos /bin/bash'.split()

# save original tty setting then set it to raw mode
old_tty = termios.tcgetattr(sys.stdin)
tty.setraw(sys.stdin.fileno())

# open pseudo-terminal to interact with subprocess
master_fd, slave_fd = pty.openpty()

# use os.setsid() make it run in a new process group, or bash job control will not be enabled
p = Popen(command,
          preexec_fn=os.setsid,
          stdin=slave_fd,
          stdout=slave_fd,
          stderr=slave_fd,
          universal_newlines=True)

while p.poll() is None:
    r, w, e = select.select([sys.stdin, master_fd], [], [])
    if sys.stdin in r:
        d = os.read(sys.stdin.fileno(), 10240)
        os.write(master_fd, d)
    elif master_fd in r:
        o = os.read(master_fd, 10240)
        if o:
            os.write(sys.stdout.fileno(), o)

# restore tty settings back
termios.tcsetattr(sys.stdin, termios.TCSADRAIN, old_tty)