现有的解决方案不适合我(详情见下文)。最后成功的是使用read(1)实现readline(基于这个答案)。后者不阻塞:

from subprocess import Popen, PIPE
from threading import Thread
def process_output(myprocess): #output-consuming thread
    nextline = None
    buf = ''
    while True:
        #--- extract line using read(1)
        out = myprocess.stdout.read(1)
        if out == '' and myprocess.poll() != None: break
        if out != '':
            buf += out
            if out == '\n':
                nextline = buf
                buf = ''
        if not nextline: continue
        line = nextline
        nextline = None

        #--- do whatever you want with line here
        print 'Line is:', line
    myprocess.stdout.close()

myprocess = Popen('myprogram.exe', stdout=PIPE) #output-producing process
p1 = Thread(target=process_output, args=(myprocess,)) #output-consuming thread
p1.daemon = True
p1.start()

#--- do whatever here and then kill process and thread if needed
if myprocess.poll() == None: #kill process; will automatically stop thread
    myprocess.kill()
    myprocess.wait()
if p1 and p1.is_alive(): #wait for thread to finish
    p1.join()

为什么现有的解决方案不起作用:

Solutions that require readline (including the Queue based ones) always block. It is difficult (impossible?) to kill the thread that executes readline. It only gets killed when the process that created it finishes, but not when the output-producing process is killed. Mixing low-level fcntl with high-level readline calls may not work properly as anonnn has pointed out. Using select.poll() is neat, but doesn't work on Windows according to python docs. Using third-party libraries seems overkill for this task and adds additional dependencies.

在我的例子中，我需要一个日志模块来捕获后台应用程序的输出并对其进行扩充(添加时间戳、颜色等)。

我最终使用了一个后台线程来执行实际的I/O操作。以下代码仅适用于POSIX平台。我去掉了不重要的部分。

如果有人打算长期使用这个野兽，可以考虑管理开放描述符。对我来说，这不是什么大问题。

# -*- python -*-
import fcntl
import threading
import sys, os, errno
import subprocess

class Logger(threading.Thread):
    def __init__(self, *modules):
        threading.Thread.__init__(self)
        try:
            from select import epoll, EPOLLIN
            self.__poll = epoll()
            self.__evt = EPOLLIN
            self.__to = -1
        except:
            from select import poll, POLLIN
            print 'epoll is not available'
            self.__poll = poll()
            self.__evt = POLLIN
            self.__to = 100
        self.__fds = {}
        self.daemon = True
        self.start()

    def run(self):
        while True:
            events = self.__poll.poll(self.__to)
            for fd, ev in events:
                if (ev&self.__evt) != self.__evt:
                    continue
                try:
                    self.__fds[fd].run()
                except Exception, e:
                    print e

    def add(self, fd, log):
        assert not self.__fds.has_key(fd)
        self.__fds[fd] = log
        self.__poll.register(fd, self.__evt)

class log:
    logger = Logger()

    def __init__(self, name):
        self.__name = name
        self.__piped = False

    def fileno(self):
        if self.__piped:
            return self.write
        self.read, self.write = os.pipe()
        fl = fcntl.fcntl(self.read, fcntl.F_GETFL)
        fcntl.fcntl(self.read, fcntl.F_SETFL, fl | os.O_NONBLOCK)
        self.fdRead = os.fdopen(self.read)
        self.logger.add(self.read, self)
        self.__piped = True
        return self.write

    def __run(self, line):
        self.chat(line, nl=False)

    def run(self):
        while True:
            try: line = self.fdRead.readline()
            except IOError, exc:
                if exc.errno == errno.EAGAIN:
                    return
                raise
            self.__run(line)

    def chat(self, line, nl=True):
        if nl: nl = '\n'
        else: nl = ''
        sys.stdout.write('[%s] %s%s' % (self.__name, line, nl))

def system(command, param=[], cwd=None, env=None, input=None, output=None):
    args = [command] + param
    p = subprocess.Popen(args, cwd=cwd, stdout=output, stderr=output, stdin=input, env=env, bufsize=0)
    p.wait()

ls = log('ls')
ls.chat('go')
system("ls", ['-l', '/'], output=ls)

date = log('date')
date.chat('go')
system("date", output=date)

You can do this really easily in Twisted. Depending upon your existing code base, this might not be that easy to use, but if you are building a twisted application, then things like this become almost trivial. You create a ProcessProtocol class, and override the outReceived() method. Twisted (depending upon the reactor used) is usually just a big select() loop with callbacks installed to handle data from different file descriptors (often network sockets). So the outReceived() method is simply installing a callback for handling data coming from STDOUT. A simple example demonstrating this behavior is as follows:

from twisted.internet import protocol, reactor

class MyProcessProtocol(protocol.ProcessProtocol):

    def outReceived(self, data):
        print data

proc = MyProcessProtocol()
reactor.spawnProcess(proc, './myprogram', ['./myprogram', 'arg1', 'arg2', 'arg3'])
reactor.run()

Twisted文档在这方面有一些很好的信息。

如果您围绕Twisted构建整个应用程序，它可以与其他进程(本地或远程)进行异步通信，就像这样非常优雅。另一方面，如果您的程序不是构建在Twisted之上，那么这真的不会有多大帮助。希望这能对其他读者有所帮助，即使它不适用于您的特定应用程序。

这是一个在子进程中执行交互命令的例子，通过伪终端实现了stdout的交互。您可以参考:https://stackoverflow.com/a/43012138/3555925

#!/usr/bin/env python
# -*- coding: utf-8 -*-

import os
import sys
import select
import termios
import tty
import pty
from subprocess import Popen

command = 'bash'
# command = 'docker run -it --rm centos /bin/bash'.split()

# save original tty setting then set it to raw mode
old_tty = termios.tcgetattr(sys.stdin)
tty.setraw(sys.stdin.fileno())

# open pseudo-terminal to interact with subprocess
master_fd, slave_fd = pty.openpty()

# use os.setsid() make it run in a new process group, or bash job control will not be enabled
p = Popen(command,
          preexec_fn=os.setsid,
          stdin=slave_fd,
          stdout=slave_fd,
          stderr=slave_fd,
          universal_newlines=True)

while p.poll() is None:
    r, w, e = select.select([sys.stdin, master_fd], [], [])
    if sys.stdin in r:
        d = os.read(sys.stdin.fileno(), 10240)
        os.write(master_fd, d)
    elif master_fd in r:
        o = os.read(master_fd, 10240)
        if o:
            os.write(sys.stdout.fileno(), o)

# restore tty settings back
termios.tcsetattr(sys.stdin, termios.TCSADRAIN, old_tty)

Fcntl, select, asyncproc在这种情况下不起作用。

不管操作系统如何，读取流而不阻塞的可靠方法是使用Queue.get_nowait():

import sys
from subprocess import PIPE, Popen
from threading  import Thread

try:
    from queue import Queue, Empty
except ImportError:
    from Queue import Queue, Empty  # python 2.x

ON_POSIX = 'posix' in sys.builtin_module_names

def enqueue_output(out, queue):
    for line in iter(out.readline, b''):
        queue.put(line)
    out.close()

p = Popen(['myprogram.exe'], stdout=PIPE, bufsize=1, close_fds=ON_POSIX)
q = Queue()
t = Thread(target=enqueue_output, args=(p.stdout, q))
t.daemon = True # thread dies with the program
t.start()

# ... do other things here

# read line without blocking
try:  line = q.get_nowait() # or q.get(timeout=.1)
except Empty:
    print('no output yet')
else: # got line
    # ... do something with line

在这里添加这个答案，因为它提供了在Windows和Unix上设置非阻塞管道的能力。

所有的ctypes细节都要感谢@techtonik的回答。

有一个稍微修改过的版本，可以在Unix和Windows系统上使用。

兼容Python3(只需要一些小的修改)。 包括posix版本，并定义了用于这两个版本的异常。

这样你就可以在Unix和Windows代码中使用相同的函数和异常。

# pipe_non_blocking.py (module)
"""
Example use:

    p = subprocess.Popen(
            command,
            stdout=subprocess.PIPE,
            )

    pipe_non_blocking_set(p.stdout.fileno())

    try:
        data = os.read(p.stdout.fileno(), 1)
    except PortableBlockingIOError as ex:
        if not pipe_non_blocking_is_error_blocking(ex):
            raise ex
"""


__all__ = (
    "pipe_non_blocking_set",
    "pipe_non_blocking_is_error_blocking",
    "PortableBlockingIOError",
    )

import os


if os.name == "nt":
    def pipe_non_blocking_set(fd):
        # Constant could define globally but avoid polluting the name-space
        # thanks to: https://stackoverflow.com/questions/34504970
        import msvcrt

        from ctypes import windll, byref, wintypes, WinError, POINTER
        from ctypes.wintypes import HANDLE, DWORD, BOOL

        LPDWORD = POINTER(DWORD)

        PIPE_NOWAIT = wintypes.DWORD(0x00000001)

        def pipe_no_wait(pipefd):
            SetNamedPipeHandleState = windll.kernel32.SetNamedPipeHandleState
            SetNamedPipeHandleState.argtypes = [HANDLE, LPDWORD, LPDWORD, LPDWORD]
            SetNamedPipeHandleState.restype = BOOL

            h = msvcrt.get_osfhandle(pipefd)

            res = windll.kernel32.SetNamedPipeHandleState(h, byref(PIPE_NOWAIT), None, None)
            if res == 0:
                print(WinError())
                return False
            return True

        return pipe_no_wait(fd)

    def pipe_non_blocking_is_error_blocking(ex):
        if not isinstance(ex, PortableBlockingIOError):
            return False
        from ctypes import GetLastError
        ERROR_NO_DATA = 232

        return (GetLastError() == ERROR_NO_DATA)

    PortableBlockingIOError = OSError
else:
    def pipe_non_blocking_set(fd):
        import fcntl
        fl = fcntl.fcntl(fd, fcntl.F_GETFL)
        fcntl.fcntl(fd, fcntl.F_SETFL, fl | os.O_NONBLOCK)
        return True

    def pipe_non_blocking_is_error_blocking(ex):
        if not isinstance(ex, PortableBlockingIOError):
            return False
        return True

    PortableBlockingIOError = BlockingIOError

为了避免读取不完整的数据，我最终编写了自己的readline生成器(它为每一行返回字节字符串)。

它是一个发电机，所以你可以例如…

def non_blocking_readlines(f, chunk=1024):
    """
    Iterate over lines, yielding b'' when nothings left
    or when new data is not yet available.

    stdout_iter = iter(non_blocking_readlines(process.stdout))

    line = next(stdout_iter)  # will be a line or b''.
    """
    import os

    from .pipe_non_blocking import (
            pipe_non_blocking_set,
            pipe_non_blocking_is_error_blocking,
            PortableBlockingIOError,
            )

    fd = f.fileno()
    pipe_non_blocking_set(fd)

    blocks = []

    while True:
        try:
            data = os.read(fd, chunk)
            if not data:
                # case were reading finishes with no trailing newline
                yield b''.join(blocks)
                blocks.clear()
        except PortableBlockingIOError as ex:
            if not pipe_non_blocking_is_error_blocking(ex):
                raise ex

            yield b''
            continue

        while True:
            n = data.find(b'\n')
            if n == -1:
                break

            yield b''.join(blocks) + data[:n + 1]
            data = data[n + 1:]
            blocks.clear()
        blocks.append(data)