Fcntl, select, asyncproc在这种情况下不起作用。

不管操作系统如何，读取流而不阻塞的可靠方法是使用Queue.get_nowait():

import sys
from subprocess import PIPE, Popen
from threading  import Thread

try:
    from queue import Queue, Empty
except ImportError:
    from Queue import Queue, Empty  # python 2.x

ON_POSIX = 'posix' in sys.builtin_module_names

def enqueue_output(out, queue):
    for line in iter(out.readline, b''):
        queue.put(line)
    out.close()

p = Popen(['myprogram.exe'], stdout=PIPE, bufsize=1, close_fds=ON_POSIX)
q = Queue()
t = Thread(target=enqueue_output, args=(p.stdout, q))
t.daemon = True # thread dies with the program
t.start()

# ... do other things here

# read line without blocking
try:  line = q.get_nowait() # or q.get(timeout=.1)
except Empty:
    print('no output yet')
else: # got line
    # ... do something with line

该解决方案使用select模块从IO流中“读取任何可用数据”。这个函数一开始会阻塞，直到数据可用，但随后只读取可用的数据，不再进一步阻塞。

鉴于它使用了select模块，这只适用于Unix。

该代码完全符合pep8。

import select


def read_available(input_stream, max_bytes=None):
    """
    Blocks until any data is available, then all available data is then read and returned.
    This function returns an empty string when end of stream is reached.

    Args:
        input_stream: The stream to read from.
        max_bytes (int|None): The maximum number of bytes to read. This function may return fewer bytes than this.

    Returns:
        str
    """
    # Prepare local variables
    input_streams = [input_stream]
    empty_list = []
    read_buffer = ""

    # Initially block for input using 'select'
    if len(select.select(input_streams, empty_list, empty_list)[0]) > 0:

        # Poll read-readiness using 'select'
        def select_func():
            return len(select.select(input_streams, empty_list, empty_list, 0)[0]) > 0

        # Create while function based on parameters
        if max_bytes is not None:
            def while_func():
                return (len(read_buffer) < max_bytes) and select_func()
        else:
            while_func = select_func

        while True:
            # Read single byte at a time
            read_data = input_stream.read(1)
            if len(read_data) == 0:
                # End of stream
                break
            # Append byte to string buffer
            read_buffer += read_data
            # Check if more data is available
            if not while_func():
                break

    # Return read buffer
    return read_buffer

在这里添加这个答案，因为它提供了在Windows和Unix上设置非阻塞管道的能力。

所有的ctypes细节都要感谢@techtonik的回答。

有一个稍微修改过的版本，可以在Unix和Windows系统上使用。

兼容Python3(只需要一些小的修改)。 包括posix版本，并定义了用于这两个版本的异常。

这样你就可以在Unix和Windows代码中使用相同的函数和异常。

# pipe_non_blocking.py (module)
"""
Example use:

    p = subprocess.Popen(
            command,
            stdout=subprocess.PIPE,
            )

    pipe_non_blocking_set(p.stdout.fileno())

    try:
        data = os.read(p.stdout.fileno(), 1)
    except PortableBlockingIOError as ex:
        if not pipe_non_blocking_is_error_blocking(ex):
            raise ex
"""


__all__ = (
    "pipe_non_blocking_set",
    "pipe_non_blocking_is_error_blocking",
    "PortableBlockingIOError",
    )

import os


if os.name == "nt":
    def pipe_non_blocking_set(fd):
        # Constant could define globally but avoid polluting the name-space
        # thanks to: https://stackoverflow.com/questions/34504970
        import msvcrt

        from ctypes import windll, byref, wintypes, WinError, POINTER
        from ctypes.wintypes import HANDLE, DWORD, BOOL

        LPDWORD = POINTER(DWORD)

        PIPE_NOWAIT = wintypes.DWORD(0x00000001)

        def pipe_no_wait(pipefd):
            SetNamedPipeHandleState = windll.kernel32.SetNamedPipeHandleState
            SetNamedPipeHandleState.argtypes = [HANDLE, LPDWORD, LPDWORD, LPDWORD]
            SetNamedPipeHandleState.restype = BOOL

            h = msvcrt.get_osfhandle(pipefd)

            res = windll.kernel32.SetNamedPipeHandleState(h, byref(PIPE_NOWAIT), None, None)
            if res == 0:
                print(WinError())
                return False
            return True

        return pipe_no_wait(fd)

    def pipe_non_blocking_is_error_blocking(ex):
        if not isinstance(ex, PortableBlockingIOError):
            return False
        from ctypes import GetLastError
        ERROR_NO_DATA = 232

        return (GetLastError() == ERROR_NO_DATA)

    PortableBlockingIOError = OSError
else:
    def pipe_non_blocking_set(fd):
        import fcntl
        fl = fcntl.fcntl(fd, fcntl.F_GETFL)
        fcntl.fcntl(fd, fcntl.F_SETFL, fl | os.O_NONBLOCK)
        return True

    def pipe_non_blocking_is_error_blocking(ex):
        if not isinstance(ex, PortableBlockingIOError):
            return False
        return True

    PortableBlockingIOError = BlockingIOError

为了避免读取不完整的数据，我最终编写了自己的readline生成器(它为每一行返回字节字符串)。

它是一个发电机，所以你可以例如…

def non_blocking_readlines(f, chunk=1024):
    """
    Iterate over lines, yielding b'' when nothings left
    or when new data is not yet available.

    stdout_iter = iter(non_blocking_readlines(process.stdout))

    line = next(stdout_iter)  # will be a line or b''.
    """
    import os

    from .pipe_non_blocking import (
            pipe_non_blocking_set,
            pipe_non_blocking_is_error_blocking,
            PortableBlockingIOError,
            )

    fd = f.fileno()
    pipe_non_blocking_set(fd)

    blocks = []

    while True:
        try:
            data = os.read(fd, chunk)
            if not data:
                # case were reading finishes with no trailing newline
                yield b''.join(blocks)
                blocks.clear()
        except PortableBlockingIOError as ex:
            if not pipe_non_blocking_is_error_blocking(ex):
                raise ex

            yield b''
            continue

        while True:
            n = data.find(b'\n')
            if n == -1:
                break

            yield b''.join(blocks) + data[:n + 1]
            data = data[n + 1:]
            blocks.clear()
        blocks.append(data)

I also faced the problem described by Jesse and solved it by using "select" as Bradley, Andy and others did but in a blocking mode to avoid a busy loop. It uses a dummy Pipe as a fake stdin. The select blocks and wait for either stdin or the pipe to be ready. When a key is pressed stdin unblocks the select and the key value can be retrieved with read(1). When a different thread writes to the pipe then the pipe unblocks the select and it can be taken as an indication that the need for stdin is over. Here is some reference code:

import sys
import os
from select import select

# -------------------------------------------------------------------------    
# Set the pipe (fake stdin) to simulate a final key stroke
# which will unblock the select statement
readEnd, writeEnd = os.pipe()
readFile = os.fdopen(readEnd)
writeFile = os.fdopen(writeEnd, "w")

# -------------------------------------------------------------------------
def getKey():

    # Wait for stdin or pipe (fake stdin) to be ready
    dr,dw,de = select([sys.__stdin__, readFile], [], [])

    # If stdin is the one ready then read it and return value
    if sys.__stdin__ in dr:
        return sys.__stdin__.read(1)   # For Windows use ----> getch() from module msvcrt

    # Must finish
    else:
        return None

# -------------------------------------------------------------------------
def breakStdinRead():
    writeFile.write(' ')
    writeFile.flush()

# -------------------------------------------------------------------------
# MAIN CODE

# Get key stroke
key = getKey()

# Keyboard input
if key:
    # ... do your stuff with the key value

# Faked keystroke
else:
    # ... use of stdin finished

# -------------------------------------------------------------------------
# OTHER THREAD CODE

breakStdinRead()

在现代Python中，情况要好得多。

下面是一个简单的子程序"hello.py":

#!/usr/bin/env python3

while True:
    i = input()
    if i == "quit":
        break
    print(f"hello {i}")

以及一个与之交互的程序:

import asyncio


async def main():
    proc = await asyncio.subprocess.create_subprocess_exec(
        "./hello.py", stdin=asyncio.subprocess.PIPE, stdout=asyncio.subprocess.PIPE
    )
    proc.stdin.write(b"bob\n")
    print(await proc.stdout.read(1024))
    proc.stdin.write(b"alice\n")
    print(await proc.stdout.read(1024))
    proc.stdin.write(b"quit\n")
    await proc.wait()


asyncio.run(main())

打印出来:

b'hello bob\n'
b'hello alice\n'

请注意，实际的模式(几乎所有前面的回答，包括这里和相关的问题)是将子进程的stdout文件描述符设置为非阻塞，然后在某种选择循环中轮询它。当然，现在这个循环是由asyncio提供的。

试试asyncproc模块。例如:

import os
from asyncproc import Process
myProc = Process("myprogram.app")

while True:
    # check to see if process has ended
    poll = myProc.wait(os.WNOHANG)
    if poll != None:
        break
    # print any new output
    out = myProc.read()
    if out != "":
        print out

该模块负责S.Lott建议的所有线程。