只要用一个减去另一个。你会得到一个timedelta对象。

>>> import datetime
>>> d1 = datetime.datetime.now()
>>> d2 = datetime.datetime.now() # after a 5-second or so pause
>>> d2 - d1
datetime.timedelta(0, 5, 203000)
>>> dd = d2 - d1
>>> print (dd.days) # get days
>>> print (dd.seconds) # get seconds
>>> print (dd.microseconds) # get microseconds
>>> print (int(round(dd.total_seconds()/60, 0))) # get minutes

这就是我如何获得两个datetime之间经过的小时数。datetime对象:

before = datetime.datetime.now()
after  = datetime.datetime.now()
hours  = math.floor(((after - before).seconds) / 3600)

使用divmod:

now = int(time.time()) # epoch seconds
then = now - 90000 # some time in the past

d = divmod(now-then,86400)  # days
h = divmod(d[1],3600)  # hours
m = divmod(h[1],60)  # minutes
s = m[1]  # seconds

print '%d days, %d hours, %d minutes, %d seconds' % (d[0],h[0],m[0],s)

Python 2.7新增了timedelta实例方法.total_seconds()。在Python文档中，这相当于(td。微秒+ (td。秒+ td。天* 24 * 3600)* 10**6)/ 10**6。

参考:http://docs.python.org/2/library/datetime.html # datetime.timedelta.total_seconds

>>> import datetime
>>> time1 = datetime.datetime.now()
>>> time2 = datetime.datetime.now() # waited a few minutes before pressing enter
>>> elapsedTime = time2 - time1
>>> elapsedTime
datetime.timedelta(0, 125, 749430)
>>> divmod(elapsedTime.total_seconds(), 60)
(2.0, 5.749430000000004) # divmod returns quotient and remainder
# 2 minutes, 5.74943 seconds

基于@Attaque的精彩回答，我提出了一个更短的简化版本的日期时差计算器:

seconds_mapping = {
    'y': 31536000,
    'm': 2628002.88, # this is approximate, 365 / 12; use with caution
    'w': 604800,
    'd': 86400,
    'h': 3600,
    'min': 60,
    's': 1,
    'mil': 0.001,
}

def get_duration(d1, d2, interval, with_reminder=False):
    if with_reminder:
        return divmod((d2 - d1).total_seconds(), seconds_mapping[interval])
    else:
        return (d2 - d1).total_seconds() / seconds_mapping[interval]

我改变了它，以避免声明重复的函数，删除了漂亮的打印默认间隔，并增加了对毫秒、周和ISO月的支持(简单地说，月只是一个近似，基于每个月等于365/12的假设)。

生产:

d1 = datetime(2011, 3, 1, 1, 1, 1, 1000)
d2 = datetime(2011, 4, 1, 1, 1, 1, 2500)

print(get_duration(d1, d2, 'y', True))      # => (0.0, 2678400.0015)
print(get_duration(d1, d2, 'm', True))      # => (1.0, 50397.12149999989)
print(get_duration(d1, d2, 'w', True))      # => (4.0, 259200.00149999978)
print(get_duration(d1, d2, 'd', True))      # => (31.0, 0.0014999997802078724)
print(get_duration(d1, d2, 'h', True))      # => (744.0, 0.0014999997802078724)
print(get_duration(d1, d2, 'min', True))    # => (44640.0, 0.0014999997802078724)
print(get_duration(d1, d2, 's', True))      # => (2678400.0, 0.0014999997802078724)
print(get_duration(d1, d2, 'mil', True))    # => (2678400001.0, 0.0004999997244524721)

print(get_duration(d1, d2, 'y', False))     # => 0.08493150689687975
print(get_duration(d1, d2, 'm', False))     # => 1.019176965856293
print(get_duration(d1, d2, 'w', False))     # => 4.428571431051587
print(get_duration(d1, d2, 'd', False))     # => 31.00000001736111
print(get_duration(d1, d2, 'h', False))     # => 744.0000004166666
print(get_duration(d1, d2, 'min', False))   # => 44640.000024999994
print(get_duration(d1, d2, 's', False))     # => 2678400.0015
print(get_duration(d1, d2, 'mil', False))   # => 2678400001.4999995

只是认为在timedelta方面提到格式化可能是有用的。Strptime()根据格式解析表示时间的字符串。

from datetime import datetime

datetimeFormat = '%Y/%m/%d %H:%M:%S.%f'    
time1 = '2016/03/16 10:01:28.585'
time2 = '2016/03/16 09:56:28.067'  
time_dif = datetime.strptime(time1, datetimeFormat) - datetime.strptime(time2,datetimeFormat)
print(time_dif)

这将输出: 0:05:00.518000