只要用一个减去另一个。你会得到一个timedelta对象。

>>> import datetime
>>> d1 = datetime.datetime.now()
>>> d2 = datetime.datetime.now() # after a 5-second or so pause
>>> d2 - d1
datetime.timedelta(0, 5, 203000)
>>> dd = d2 - d1
>>> print (dd.days) # get days
>>> print (dd.seconds) # get seconds
>>> print (dd.microseconds) # get microseconds
>>> print (int(round(dd.total_seconds()/60, 0))) # get minutes

这是我使用mktime的方法。

from datetime import datetime, timedelta
from time import mktime

yesterday = datetime.now() - timedelta(days=1)
today = datetime.now()

difference_in_seconds = abs(mktime(yesterday.timetuple()) - mktime(today.timetuple()))
difference_in_minutes = difference_in_seconds / 60

如果a, b是datetime对象，那么在Python 3中查找它们之间的时间差:

from datetime import timedelta

time_difference = a - b
time_difference_in_minutes = time_difference / timedelta(minutes=1)

在早期的Python版本中:

time_difference_in_minutes = time_difference.total_seconds() / 60

如果a, b是天真的datetime对象，例如datetime.now()返回的，那么如果对象表示具有不同UTC偏移量的本地时间，例如DST转换前后或过去/未来日期，则结果可能是错误的。更多细节:查找datetimes之间是否已经过了24小时- Python。

要获得可靠的结果，请使用UTC时间或时区感知的datetime对象。

Python 2.7新增了timedelta实例方法.total_seconds()。在Python文档中，这相当于(td。微秒+ (td。秒+ td。天* 24 * 3600)* 10**6)/ 10**6。

参考:http://docs.python.org/2/library/datetime.html # datetime.timedelta.total_seconds

>>> import datetime
>>> time1 = datetime.datetime.now()
>>> time2 = datetime.datetime.now() # waited a few minutes before pressing enter
>>> elapsedTime = time2 - time1
>>> elapsedTime
datetime.timedelta(0, 125, 749430)
>>> divmod(elapsedTime.total_seconds(), 60)
(2.0, 5.749430000000004) # divmod returns quotient and remainder
# 2 minutes, 5.74943 seconds

要查找天数:timedelta有一个'days'属性。你可以简单地查询一下。

>>>from datetime import datetime, timedelta
>>>d1 = datetime(2015, 9, 12, 13, 9, 45)
>>>d2 = datetime(2015, 8, 29, 21, 10, 12)
>>>d3 = d1- d2
>>>print d3
13 days, 15:59:33
>>>print d3.days
13

使用divmod:

now = int(time.time()) # epoch seconds
then = now - 90000 # some time in the past

d = divmod(now-then,86400)  # days
h = divmod(d[1],3600)  # hours
m = divmod(h[1],60)  # minutes
s = m[1]  # seconds

print '%d days, %d hours, %d minutes, %d seconds' % (d[0],h[0],m[0],s)