这是我在swift中的解决方案。子类应该同时适用于attributedText和text属性以及characterSpacing + lineSpacing。如果设置了新字符串或attributedString，则保留空格。

open class UHBCustomLabel : UILabel {
    @IBInspectable open var characterSpacing:CGFloat = 1 {
        didSet {
            updateWithSpacing()
        }

    }
    @IBInspectable open var lines_spacing:CGFloat = -1 {
        didSet {
            updateWithSpacing()
        }

    }
    open override var text: String? {
        set {
            super.text = newValue
            updateWithSpacing()
        }
        get {
            return super.text
        }
    }
    open override var attributedText: NSAttributedString? {
        set {
            super.attributedText = newValue
            updateWithSpacing() 
        }
        get {
            return super.attributedText
        }
    }
    func updateWithSpacing() {
        let attributedString = self.attributedText == nil ? NSMutableAttributedString(string: self.text ?? "") : NSMutableAttributedString(attributedString: attributedText!)
        attributedString.addAttribute(NSKernAttributeName, value: self.characterSpacing, range: NSRange(location: 0, length: attributedString.length))
        if lines_spacing >= 0 {
            let paragraphStyle = NSMutableParagraphStyle()
            paragraphStyle.lineSpacing = lines_spacing
            paragraphStyle.alignment = textAlignment
            attributedString.addAttribute(NSParagraphStyleAttributeName, value:paragraphStyle, range:NSMakeRange(0, attributedString.length))
        }
        super.attributedText = attributedString
    }
}

SWIFT 3有用的扩展设置行间的空间更容易:)

extension UILabel
{
    func setLineHeight(lineHeight: CGFloat)
    {
        let text = self.text
        if let text = text 
        {

            let attributeString = NSMutableAttributedString(string: text)
            let style = NSMutableParagraphStyle()

           style.lineSpacing = lineHeight
           attributeString.addAttribute(NSParagraphStyleAttributeName,
                                        value: style,
                                        range: NSMakeRange(0, text.characters.count))

           self.attributedText = attributeString
        }
    }
}

这段代码适用于我(ios 7和ios 8肯定是如此)。

_label.numberOfLines=2;
_label.textColor=[UIColor whiteColor];

NSMutableParagraphStyle *paragraphStyle = [[NSMutableParagraphStyle alloc] init];
paragraphStyle.lineHeightMultiple=0.5;
paragraphStyle.alignment = NSTextAlignmentCenter;
paragraphStyle.lineSpacing = 1.0;

NSDictionary *nameAttributes=@{
                               NSParagraphStyleAttributeName : paragraphStyle,
                               NSBaselineOffsetAttributeName:@2.0
                               };


NSAttributedString *string=[[NSAttributedString alloc] initWithString:@"22m\nago" attributes:nameAttributes];
_label.attributedText=string;

下面是UILabel的一个子类，它设置lineHeightMultiple并确保内在高度足够大，不会截断文本。

@IBDesignable
class Label: UILabel {
    override var intrinsicContentSize: CGSize {
        var size = super.intrinsicContentSize
        let padding = (1.0 - lineHeightMultiple) * font.pointSize
        size.height += padding
        return size
    }

    override var text: String? {
        didSet {
            updateAttributedText()
        }
    }

    @IBInspectable var lineHeightMultiple: CGFloat = 1.0 {
        didSet {
            updateAttributedText()
        }
    }

    private func updateAttributedText() {
        let paragraphStyle = NSMutableParagraphStyle()
        paragraphStyle.lineHeightMultiple = lineHeightMultiple
        attributedText = NSAttributedString(string: text ?? "", attributes: [
            .font: font,
            .paragraphStyle: paragraphStyle,
            .foregroundColor: textColor
        ])
        invalidateIntrinsicContentSize()
    }
}

从ios6开始，你可以为UILabel设置带属性字符串。检查以下内容:

NSMutableAttributedString *attributedString = [[NSMutableAttributedString alloc] initWithString:label.text];
NSMutableParagraphStyle *paragraphStyle = [[NSMutableParagraphStyle alloc] init];
paragraphStyle.lineSpacing = spacing;
[attributedString addAttribute:NSParagraphStyleAttributeName value:paragraphStyle range:NSMakeRange(0, label.text.length)];

label.attributedText = attributedString;

我想在这个答案中加入一些新的东西，这样我就不会感觉那么糟糕了……以下是斯威夫特的回答:

import Cocoa

let paragraphStyle = NSMutableParagraphStyle()
paragraphStyle.lineSpacing = 40

let attrString = NSMutableAttributedString(string: "Swift Answer")
attrString.addAttribute(.paragraphStyle, value:paragraphStyle, range:NSMakeRange(0, attrString.length))

var tableViewCell = NSTableCellView()
tableViewCell.textField.attributedStringValue = attrString

简单的回答是:你不能。要改变文本行间的间距，你必须继承UILabel并滚动自己的drawTextInRect，或者创建多个标签。”

参见:设置UILabel行间距

这是一个非常老的答案，其他人已经添加了新的更好的方法来处理这个问题。请参阅下面提供的最新答案。