在ios6中有另一个答案，那就是在标签上设置attributedText，使用NSAttributedString和适当的段落样式。关于NSAttributedString的行高，请参阅堆栈溢出答案:

NSAttributedString行高，对吗?

这段代码适用于我(ios 7和ios 8肯定是如此)。

_label.numberOfLines=2;
_label.textColor=[UIColor whiteColor];

NSMutableParagraphStyle *paragraphStyle = [[NSMutableParagraphStyle alloc] init];
paragraphStyle.lineHeightMultiple=0.5;
paragraphStyle.alignment = NSTextAlignmentCenter;
paragraphStyle.lineSpacing = 1.0;

NSDictionary *nameAttributes=@{
                               NSParagraphStyleAttributeName : paragraphStyle,
                               NSBaselineOffsetAttributeName:@2.0
                               };


NSAttributedString *string=[[NSAttributedString alloc] initWithString:@"22m\nago" attributes:nameAttributes];
_label.attributedText=string;

从接口生成器(Storyboard/XIB):

编程:

斯威夫特4

使用标签扩展

extension UILabel {

    // Pass value for any one of both parameters and see result
    func setLineSpacing(lineSpacing: CGFloat = 0.0, lineHeightMultiple: CGFloat = 0.0) {

        guard let labelText = self.text else { return }

        let paragraphStyle = NSMutableParagraphStyle()
        paragraphStyle.lineSpacing = lineSpacing
        paragraphStyle.lineHeightMultiple = lineHeightMultiple

        let attributedString:NSMutableAttributedString
        if let labelattributedText = self.attributedText {
            attributedString = NSMutableAttributedString(attributedString: labelattributedText)
        } else {
            attributedString = NSMutableAttributedString(string: labelText)
        }

        // Line spacing attribute
        attributedString.addAttribute(NSAttributedStringKey.paragraphStyle, value:paragraphStyle, range:NSMakeRange(0, attributedString.length))

        self.attributedText = attributedString
    }
}

现在调用扩展函数

let label = UILabel()
let stringValue = "How to\ncontrol\nthe\nline spacing\nin UILabel"

// Pass value for any one argument - lineSpacing or lineHeightMultiple
label.setLineSpacing(lineSpacing: 2.0) .  // try values 1.0 to 5.0

// or try lineHeightMultiple
//label.setLineSpacing(lineHeightMultiple = 2.0) // try values 0.5 to 2.0

或者使用标签实例(只要复制并执行这段代码就可以看到结果)

let label = UILabel()
let stringValue = "How to\ncontrol\nthe\nline spacing\nin UILabel"
let attrString = NSMutableAttributedString(string: stringValue)
var style = NSMutableParagraphStyle()
style.lineSpacing = 24 // change line spacing between paragraph like 36 or 48
style.minimumLineHeight = 20 // change line spacing between each line like 30 or 40

// Line spacing attribute
attrString.addAttribute(NSAttributedStringKey.paragraphStyle, value: style, range: NSRange(location: 0, length: stringValue.characters.count))

// Character spacing attribute
attrString.addAttribute(NSAttributedStringKey.kern, value: 2, range: NSMakeRange(0, attrString.length))

label.attributedText = attrString

斯威夫特3

let label = UILabel()
let stringValue = "How to\ncontrol\nthe\nline spacing\nin UILabel"
let attrString = NSMutableAttributedString(string: stringValue)
var style = NSMutableParagraphStyle()
style.lineSpacing = 24 // change line spacing between paragraph like 36 or 48
style.minimumLineHeight = 20 // change line spacing between each line like 30 or 40
attrString.addAttribute(NSParagraphStyleAttributeName, value: style, range: NSRange(location: 0, length: stringValue.characters.count))
label.attributedText = attrString

根据@Mike的回答，减少lineHeightMultiple是关键点。下面的例子，它很适合我:

NSString* text = label.text;
CGFloat textWidth = [text sizeWithAttributes:@{NSFontAttributeName: label.font}].width;
if (textWidth > label.frame.size.width) {
  NSMutableParagraphStyle *paragraph = [[NSMutableParagraphStyle alloc] init];
  paragraph.alignment = NSTextAlignmentCenter;
  paragraph.lineSpacing = 1.0f;
  paragraph.lineHeightMultiple = 0.75;     // Reduce this value !!!
  NSMutableAttributedString* attrText = [[NSMutableAttributedString alloc] initWithString:text];
  [attrText addAttribute:NSParagraphStyleAttributeName value:paragraph range:NSMakeRange(0, text.length)];
  label.attributedText = attrText;
}

Swift 4标签扩展。在传入函数之前创建NSMutableAttributedString，以防有属性文本需要额外的属性。

extension UILabel {

    func setLineHeightMultiple(to height: CGFloat, withAttributedText attributedText: NSMutableAttributedString) {

        let paragraphStyle = NSMutableParagraphStyle()
        paragraphStyle.lineSpacing = 1.0
        paragraphStyle.lineHeightMultiple = height
        paragraphStyle.alignment = textAlignment

        attributedText.addAttribute(.paragraphStyle, value: paragraphStyle, range: NSRange(location: 0, length: attributedText.length - 1))

        self.attributedText = attributedText
    }
}

在ios6中有另一个答案，那就是在标签上设置attributedText，使用NSAttributedString和适当的段落样式。关于NSAttributedString的行高，请参阅堆栈溢出答案:

NSAttributedString行高，对吗?