根据@Mike的回答，减少lineHeightMultiple是关键点。下面的例子，它很适合我:

NSString* text = label.text;
CGFloat textWidth = [text sizeWithAttributes:@{NSFontAttributeName: label.font}].width;
if (textWidth > label.frame.size.width) {
  NSMutableParagraphStyle *paragraph = [[NSMutableParagraphStyle alloc] init];
  paragraph.alignment = NSTextAlignmentCenter;
  paragraph.lineSpacing = 1.0f;
  paragraph.lineHeightMultiple = 0.75;     // Reduce this value !!!
  NSMutableAttributedString* attrText = [[NSMutableAttributedString alloc] initWithString:text];
  [attrText addAttribute:NSParagraphStyleAttributeName value:paragraph range:NSMakeRange(0, text.length)];
  label.attributedText = attrText;
}

我做了这个简单的扩展，非常适合我:

extension UILabel {
    func setLineHeight(lineHeight: CGFloat) {
        let paragraphStyle = NSMutableParagraphStyle()
        paragraphStyle.lineSpacing = 1.0
        paragraphStyle.lineHeightMultiple = lineHeight
        paragraphStyle.alignment = self.textAlignment

        let attrString = NSMutableAttributedString()
        if (self.attributedText != nil) {
            attrString.append( self.attributedText!)
        } else {
            attrString.append( NSMutableAttributedString(string: self.text!))
            attrString.addAttribute(NSAttributedStringKey.font, value: self.font, range: NSMakeRange(0, attrString.length))
        }
        attrString.addAttribute(NSAttributedStringKey.paragraphStyle, value:paragraphStyle, range:NSMakeRange(0, attrString.length))
        self.attributedText = attrString
    }
}

复制到一个文件中，这样你就可以像这样使用它了

myLabel.setLineHeight(0.7)

Swift 3扩展:

import UIKit
    
extension UILabel {
  func setTextWithLineSpacing(text: String, lineHeightMultiply: CGFloat = 1.3) {
    let paragraphStyle = NSMutableParagraphStyle()
    paragraphStyle.lineHeightMultiple = lineHeightMultiply
    paragraphStyle.alignment = .center
    let attributedString = NSMutableAttributedString(string: text)
    attributedString.addAttribute(NSParagraphStyleAttributeName, value: paragraphStyle, range: NSRange(location: 0, length: attributedString.length))
    self.attributedText = attributedString
  }
}

下面是一个子类UILabel具有行高属性的类:https://github.com/LemonCake/MSLabel

这是我在swift中的解决方案。子类应该同时适用于attributedText和text属性以及characterSpacing + lineSpacing。如果设置了新字符串或attributedString，则保留空格。

open class UHBCustomLabel : UILabel {
    @IBInspectable open var characterSpacing:CGFloat = 1 {
        didSet {
            updateWithSpacing()
        }

    }
    @IBInspectable open var lines_spacing:CGFloat = -1 {
        didSet {
            updateWithSpacing()
        }

    }
    open override var text: String? {
        set {
            super.text = newValue
            updateWithSpacing()
        }
        get {
            return super.text
        }
    }
    open override var attributedText: NSAttributedString? {
        set {
            super.attributedText = newValue
            updateWithSpacing() 
        }
        get {
            return super.attributedText
        }
    }
    func updateWithSpacing() {
        let attributedString = self.attributedText == nil ? NSMutableAttributedString(string: self.text ?? "") : NSMutableAttributedString(attributedString: attributedText!)
        attributedString.addAttribute(NSKernAttributeName, value: self.characterSpacing, range: NSRange(location: 0, length: attributedString.length))
        if lines_spacing >= 0 {
            let paragraphStyle = NSMutableParagraphStyle()
            paragraphStyle.lineSpacing = lines_spacing
            paragraphStyle.alignment = textAlignment
            attributedString.addAttribute(NSParagraphStyleAttributeName, value:paragraphStyle, range:NSMakeRange(0, attributedString.length))
        }
        super.attributedText = attributedString
    }
}

SWIFT 3有用的扩展设置行间的空间更容易:)

extension UILabel
{
    func setLineHeight(lineHeight: CGFloat)
    {
        let text = self.text
        if let text = text 
        {

            let attributeString = NSMutableAttributedString(string: text)
            let style = NSMutableParagraphStyle()

           style.lineSpacing = lineHeight
           attributeString.addAttribute(NSParagraphStyleAttributeName,
                                        value: style,
                                        range: NSMakeRange(0, text.characters.count))

           self.attributedText = attributeString
        }
    }
}