另一个答案……如果你通过编程的方式传递字符串，你需要传递一个带属性的字符串，而不是一个普通的字符串，并改变它的风格。

NSMutableAttributedString * attrString = [[NSMutableAttributedString alloc] initWithString:@"Your \nregular \nstring"];
NSMutableParagraphStyle *style = [[NSMutableParagraphStyle alloc] init];
[style setLineSpacing:4];
[attrString addAttribute:NSParagraphStyleAttributeName
                   value:style
                   range:NSMakeRange(0, attrString.length)];
_label.attributedText = attrString;

在Swift中，作为一个函数，灵感来自DarkDust

// Usage: setTextWithLineSpacing(myEpicUILabel,text:"Hello",lineSpacing:20)
func setTextWithLineSpacing(label:UILabel,text:String,lineSpacing:CGFloat)
{
    let paragraphStyle = NSMutableParagraphStyle()
    paragraphStyle.lineSpacing = lineSpacing

    let attrString = NSMutableAttributedString(string: text)
    attrString.addAttribute(NSAttributedString.Key.paragraphStyle, value:paragraphStyle, range:NSMakeRange(0, attrString.length))

    label.attributedText = attrString
}

这里提到的解决方案对我不起作用。我发现了一个稍微不同的方式来做它与iOS 6 NSAttributeString:

myLabel.numberOfLines = 0; 
NSString* string = @"String with line one. \n Line two. \n Line three.";
NSMutableParagraphStyle *style  = [[NSMutableParagraphStyle alloc] init];
style.minimumLineHeight = 30.f;
style.maximumLineHeight = 30.f;
NSDictionary *attributtes = @{NSParagraphStyleAttributeName : style,};
myLabel.attributedText = [[NSAttributedString alloc] initWithString:string
                                                         attributes:attributtes];   
[myLabel sizeToFit];

我做了这个简单的扩展，非常适合我:

extension UILabel {
    func setLineHeight(lineHeight: CGFloat) {
        let paragraphStyle = NSMutableParagraphStyle()
        paragraphStyle.lineSpacing = 1.0
        paragraphStyle.lineHeightMultiple = lineHeight
        paragraphStyle.alignment = self.textAlignment

        let attrString = NSMutableAttributedString()
        if (self.attributedText != nil) {
            attrString.append( self.attributedText!)
        } else {
            attrString.append( NSMutableAttributedString(string: self.text!))
            attrString.addAttribute(NSAttributedStringKey.font, value: self.font, range: NSMakeRange(0, attrString.length))
        }
        attrString.addAttribute(NSAttributedStringKey.paragraphStyle, value:paragraphStyle, range:NSMakeRange(0, attrString.length))
        self.attributedText = attrString
    }
}

复制到一个文件中，这样你就可以像这样使用它了

myLabel.setLineHeight(0.7)

从ios6开始，你可以为UILabel设置带属性字符串。检查以下内容:

NSMutableAttributedString *attributedString = [[NSMutableAttributedString alloc] initWithString:label.text];
NSMutableParagraphStyle *paragraphStyle = [[NSMutableParagraphStyle alloc] init];
paragraphStyle.lineSpacing = spacing;
[attributedString addAttribute:NSParagraphStyleAttributeName value:paragraphStyle range:NSMakeRange(0, label.text.length)];

label.attributedText = attributedString;

根据@Mike的回答，减少lineHeightMultiple是关键点。下面的例子，它很适合我:

NSString* text = label.text;
CGFloat textWidth = [text sizeWithAttributes:@{NSFontAttributeName: label.font}].width;
if (textWidth > label.frame.size.width) {
  NSMutableParagraphStyle *paragraph = [[NSMutableParagraphStyle alloc] init];
  paragraph.alignment = NSTextAlignmentCenter;
  paragraph.lineSpacing = 1.0f;
  paragraph.lineHeightMultiple = 0.75;     // Reduce this value !!!
  NSMutableAttributedString* attrText = [[NSMutableAttributedString alloc] initWithString:text];
  [attrText addAttribute:NSParagraphStyleAttributeName value:paragraph range:NSMakeRange(0, text.length)];
  label.attributedText = attrText;
}