另一个答案……如果你通过编程的方式传递字符串，你需要传递一个带属性的字符串，而不是一个普通的字符串，并改变它的风格。

NSMutableAttributedString * attrString = [[NSMutableAttributedString alloc] initWithString:@"Your \nregular \nstring"];
NSMutableParagraphStyle *style = [[NSMutableParagraphStyle alloc] init];
[style setLineSpacing:4];
[attrString addAttribute:NSParagraphStyleAttributeName
                   value:style
                   range:NSMakeRange(0, attrString.length)];
_label.attributedText = attrString;

从ios6开始，你可以为UILabel设置带属性字符串。检查以下内容:

NSMutableAttributedString *attributedString = [[NSMutableAttributedString alloc] initWithString:label.text];
NSMutableParagraphStyle *paragraphStyle = [[NSMutableParagraphStyle alloc] init];
paragraphStyle.lineSpacing = spacing;
[attributedString addAttribute:NSParagraphStyleAttributeName value:paragraphStyle range:NSMakeRange(0, label.text.length)];

label.attributedText = attributedString;

在Swift中，作为一个函数，灵感来自DarkDust

// Usage: setTextWithLineSpacing(myEpicUILabel,text:"Hello",lineSpacing:20)
func setTextWithLineSpacing(label:UILabel,text:String,lineSpacing:CGFloat)
{
    let paragraphStyle = NSMutableParagraphStyle()
    paragraphStyle.lineSpacing = lineSpacing

    let attrString = NSMutableAttributedString(string: text)
    attrString.addAttribute(NSAttributedString.Key.paragraphStyle, value:paragraphStyle, range:NSMakeRange(0, attrString.length))

    label.attributedText = attrString
}

SWIFT 3有用的扩展设置行间的空间更容易:)

extension UILabel
{
    func setLineHeight(lineHeight: CGFloat)
    {
        let text = self.text
        if let text = text 
        {

            let attributeString = NSMutableAttributedString(string: text)
            let style = NSMutableParagraphStyle()

           style.lineSpacing = lineHeight
           attributeString.addAttribute(NSParagraphStyleAttributeName,
                                        value: style,
                                        range: NSMakeRange(0, text.characters.count))

           self.attributedText = attributeString
        }
    }
}

在ios6中有另一个答案，那就是在标签上设置attributedText，使用NSAttributedString和适当的段落样式。关于NSAttributedString的行高，请参阅堆栈溢出答案:

NSAttributedString行高，对吗?

Swift 4标签扩展。在传入函数之前创建NSMutableAttributedString，以防有属性文本需要额外的属性。

extension UILabel {

    func setLineHeightMultiple(to height: CGFloat, withAttributedText attributedText: NSMutableAttributedString) {

        let paragraphStyle = NSMutableParagraphStyle()
        paragraphStyle.lineSpacing = 1.0
        paragraphStyle.lineHeightMultiple = height
        paragraphStyle.alignment = textAlignment

        attributedText.addAttribute(.paragraphStyle, value: paragraphStyle, range: NSRange(location: 0, length: attributedText.length - 1))

        self.attributedText = attributedText
    }
}