你也可以使用pathlib。

from pathlib2 import Path
path = Path(file_to_search)
text = path.read_text()
text = text.replace(text_to_search, replacement_text)
path.write_text(text)

Besides the answers already mentioned, here is an explanation of why you have some random characters at the end: You are opening the file in r+ mode, not w mode. The key difference is that w mode clears the contents of the file as soon as you open it, whereas r+ doesn't. This means that if your file content is "123456789" and you write "www" to it, you get "www456789". It overwrites the characters with the new input, but leaves any remaining input untouched. You can clear a section of the file contents by using truncate(<startPosition>), but you are probably best off saving the updated file content to a string first, then doing truncate(0) and writing it all at once. Or you can use my library :D

Fileinput已经支持就地编辑。在这种情况下，它将stdout重定向到文件:

#!/usr/bin/env python3
import fileinput

with fileinput.FileInput(filename, inplace=True, backup='.bak') as file:
    for line in file:
        print(line.replace(text_to_search, replacement_text), end='')

我也有同样的问题。问题是，当你在变量中加载一个.txt时，你把它当作一个字符串数组使用，而它是一个字符数组。

swapString = []
with open(filepath) as f: 
    s = f.read()
for each in s:
    swapString.append(str(each).replace('this','that'))
s = swapString
print(s)

我已经把这个作为一个课程的练习:打开文件，找到并替换字符串，并写入一个新文件。

class Letter:

    def __init__(self):

        with open("./Input/Names/invited_names.txt", "r") as file:
            # read the list of names
            list_names = [line.rstrip() for line in file]
            with open("./Input/Letters/starting_letter.docx", "r") as f:
                # read letter
                file_source = f.read()
            for name in list_names:
                with open(f"./Output/ReadyToSend/LetterTo{name}.docx", "w") as f:
                    # replace [name] with name of the list in the file
                    replace_string = file_source.replace('[name]', name)
                    # write to a new file
                    f.write(replace_string)


brief = Letter()

使用re.subn可以对替换过程进行更多的控制，例如将单词分成两行，区分大小写的匹配。此外，它返回匹配的数量，如果没有找到字符串，可以使用这些匹配来避免浪费资源。

import re

file = # path to file

# they can be also raw string and regex
textToSearch = r'Ha.*O' # here an example with a regex
textToReplace = 'hallo'

# read and replace
with open(file, 'r') as fd:
    # sample case-insensitive find-and-replace
    text, counter = re.subn(textToSearch, textToReplace, fd.read(), re.I)

# check if there is at least a  match
if counter > 0:
    # edit the file
    with open(file, 'w') as fd:
        fd.write(text)

# summary result
print(f'{counter} occurence of "{textToSearch}" were replaced with "{textToReplace}".')

一些正则表达式:

添加re.I标志，re.IGNORECASE的缩写形式，用于不区分大小写的匹配 对于多行替换re.subn(r'\n*'.join(textToSearch)， textToReplace, fd.read()))，取决于数据也'\n{，1}'。注意，在这种情况下，textToSearch必须是纯字符串，而不是正则表达式!