您的问题源于读取和写入同一个文件。与其打开fileToSearch进行写入，不如打开一个实际的临时文件，然后在您完成并关闭tempFile之后，使用os。rename将新文件移动到fileToSearch上。

我稍微修改了Jayram Singh的帖子，以替换每一个'!'字符转换为一个数字，我想在每个实例中增加这个数字。我想这对那些想要修改每行出现不止一次的字符并且想要迭代的人可能会有帮助。希望这能帮助到别人。PS-我在编码方面很新，所以如果我的帖子在任何方面都不合适，我很抱歉，但这对我来说是有效的。

f1 = open('file1.txt', 'r')
f2 = open('file2.txt', 'w')
n = 1  

# if word=='!'replace w/ [n] & increment n; else append same word to     
# file2

for line in f1:
    for word in line:
        if word == '!':
            f2.write(word.replace('!', f'[{n}]'))
            n += 1
        else:
            f2.write(word)
f1.close()
f2.close()

我是这样做的:

#!/usr/bin/env python3

import fileinput
import os

Dir = input ("Source directory: ")
os.chdir(Dir)

Filelist = os.listdir()
print('File list: ',Filelist)

NomeFile = input ("Insert file name: ")

CarOr = input ("Text to search: ")

CarNew = input ("New text: ")

with fileinput.FileInput(NomeFile, inplace=True, backup='.bak') as file:
    for line in file:
        print(line.replace(CarOr, CarNew), end='')

file.close ()

我已经把这个作为一个课程的练习:打开文件，找到并替换字符串，并写入一个新文件。

class Letter:

    def __init__(self):

        with open("./Input/Names/invited_names.txt", "r") as file:
            # read the list of names
            list_names = [line.rstrip() for line in file]
            with open("./Input/Letters/starting_letter.docx", "r") as f:
                # read letter
                file_source = f.read()
            for name in list_names:
                with open(f"./Output/ReadyToSend/LetterTo{name}.docx", "w") as f:
                    # replace [name] with name of the list in the file
                    replace_string = file_source.replace('[name]', name)
                    # write to a new file
                    f.write(replace_string)


brief = Letter()

(pip install python-util)

from pyutil import filereplace

filereplace("somefile.txt","abcd","ram")

将所有出现的“abcd”替换为“ram”。 该函数还通过指定regex=True来支持regex

from pyutil import filereplace

filereplace("somefile.txt","\\w+","ram",regex=True)

免责声明:我是作者(https://github.com/MisterL2/python-util)

像这样:

def find_and_replace(file, word, replacement):
  with open(file, 'r+') as f:
    text = f.read()
    f.write(text.replace(word, replacement))